toll-like receptor 9

詳細情報を見る

同義遺伝子名

CD289, UNQ5798/PRO19605, TLR9, CD289 antigen, toll-like receptor 9, Toll-like receptor 9 precursor

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:2.40 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:20.20 末梢血:18.20 脾臓:- 胸腺:12.90 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip nodata
CAGE 大脳:0 小脳:- 脳幹:0 脳梁:0 松果体:0 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0.34 静脈:2.75 リンパ節:3.02 末梢血:- 脾臓:3.32 胸腺:2.12 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0.05 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.22 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.04 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:14.70    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip nodata
CAGE 子宮:0.10 胎盤:0.16 前立腺:0.49 卵巣:0.37 精巣:0.25 心臓:0 骨格筋:0 食道:0.77 胃:- 腸:1.31 結腸:1.23     肝臓:0    肺:0.68 膀胱:0.53 腎臓:0.27 下垂体:0 甲状腺:0 副腎:- 膵臓:0 乳腺:0 唾液腺:0.83
RNA-seq 子宮:- 胎盤:- 前立腺:0.39 卵巣:0.57 精巣:0.15 心臓:0.03 骨格筋:0.48 食道:- 胃:- 腸:- 結腸:0.25     肝臓:0.04        肺:0.16    膀胱:- 腎臓:0.09 下垂体:- 甲状腺:0.28 副腎:1.41 膵臓:- 乳腺:0.14 唾液腺:-

IDs

Refseq ID NM_017442
Gene ID 54106
Unigene ID Hs.87968
Probe set ID -
Ensembl ID ENSG00000239732
GTEx ID ENSG00000239732

オーソログ対応遺伝子

マウス[1]  NM_031178
ラット[1]  NM_031178

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0042742  defense response to bacterium
GO:0007252  I-kappaB phosphorylation
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0008286  insulin receptor signaling pathway
GO:0030277  maintenance of gastrointestinal epithelium
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0032715  negative regulation of interleukin-6 production
GO:0032717  negative regulation of interleukin-8 production
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0034122  negative regulation of toll-like receptor signaling pathway
GO:0032722  positive regulation of chemokine production
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050729  positive regulation of inflammatory response
GO:0045356  positive regulation of interferon-alpha biosynthetic process
GO:0045359  positive regulation of interferon-beta biosynthetic process
GO:0032728  positive regulation of interferon-beta production
GO:0045078  positive regulation of interferon-gamma biosynthetic process
GO:0032733  positive regulation of interleukin-10 production
GO:0032735  positive regulation of interleukin-12 production
GO:0032741  positive regulation of interleukin-18 production
GO:0032755  positive regulation of interleukin-6 production
GO:0032757  positive regulation of interleukin-8 production
GO:0046330  positive regulation of JNK cascade
GO:0043507  positive regulation of JUN kinase activity
GO:0042346  positive regulation of NF-kappaB import into nucleus
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0051770  positive regulation of nitric-oxide synthase biosynthetic process
GO:0034123  positive regulation of toll-like receptor signaling pathway
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0032760  positive regulation of tumor necrosis factor production
GO:0050707  regulation of cytokine secretion
GO:0002237  response to molecule of bacterial origin
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0005737  cytoplasm
GO:0032009  early phagosome
GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0005768  endosome
GO:0010008  endosome membrane
GO:0005576  extracellular region
GO:0000139  Golgi membrane
GO:0016021  integral to membrane
GO:0005764  lysosome
GO:0005886  plasma membrane

Molecular Function

GO:0005149  interleukin-1 receptor binding
GO:0035197  siRNA binding
GO:0004888  transmembrane receptor activity