protein kinase, cAMP-dependent, catalytic, alpha

詳細情報を見る

同義遺伝子名

MGC102831, protein kinase, cAMP-dependent, catalytic, alpha, MGC48865, PKA C-alpha, PRKACA, buthionine sulfoximine (BSO), PKACA, cAMP-dependent protein kinase (PKAc)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:28.40 小脳:12.60 脳幹:- 脳梁:29.20 松果体:- 末梢神経:92 脊柱:449.20 網膜:- 目:117.50 動脈:- 静脈:- リンパ節:30.30 末梢血:- 脾臓:37.80 胸腺:25.80 骨髄:39.40 脂肪:40.30 骨:89.60 皮膚:33.60
GeneChip 大脳:7.93 小脳:7.83 脳幹:8.02 脳梁:7.49 松果体:- 末梢神経:8.04 脊柱:7.85 網膜:- 目:- 動脈:8.19 静脈:8 リンパ節:7.70 末梢血:- 脾臓:8.33 胸腺:6.61 骨髄:7.09 脂肪:8.23 骨:- 皮膚:7.46
CAGE 大脳:4.65 小脳:- 脳幹:4.39 脳梁:4.31 松果体:4.79 末梢神経:- 脊柱:4.38 網膜:- 目:- 動脈:4.80 静脈:4.34 リンパ節:4.26 末梢血:- 脾臓:4.95 胸腺:4.02 骨髄:- 脂肪:4.43 骨:- 皮膚:-
RNA-seq 大脳:1.47 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.73 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.53 骨:- 皮膚:-
EST 子宮:36.50 胎盤:18.20 前立腺:22.50 卵巣:- 精巣:69.20 心臓:89.40 骨格筋:40.20 食道:- 胃:- 腸:- 結腸:17     肝臓:21.10        肺:53.80    膀胱:- 腎臓:41.60 下垂体:232 甲状腺:- 副腎:50.80 膵臓:88.90 乳腺:111.50 唾液腺:-
GeneChip 子宮:7.51 胎盤:7.24 前立腺:7.19 卵巣:7.66 精巣:8.27 心臓:8.74 骨格筋:8.23 食道:7.81 胃:7.49 腸:7.48 結腸:7.63 肝臓:8.16 肺:7.49 膀胱:- 腎臓:7.66 下垂体:8.40 甲状腺:7.68 副腎:8.74 膵臓:7.17 乳腺:7.92 唾液腺:7.72
CAGE 子宮:4.33 胎盤:3.76 前立腺:4.38 卵巣:5.05 精巣:4.88 心臓:5.41 骨格筋:5.00 食道:4.36 胃:- 腸:4.15 結腸:4.54     肝臓:4.84    肺:4.30 膀胱:4.54 腎臓:4.15 下垂体:4.55 甲状腺:4.16 副腎:- 膵臓:4.18 乳腺:5.03 唾液腺:3.97
RNA-seq 子宮:- 胎盤:- 前立腺:2.07 卵巣:2.51 精巣:1.27 心臓:2.86 骨格筋:3.78 食道:- 胃:- 腸:- 結腸:1.22     肝臓:1.53        肺:2.14    膀胱:- 腎臓:0.86 下垂体:- 甲状腺:2.26 副腎:1.56 膵臓:- 乳腺:2.05 唾液腺:-

IDs

Refseq ID NM_002730
Gene ID 5566
Unigene ID Hs.631630
Probe set ID 202801_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000072062
GTEx ID ENSG00000072062

オーソログ対応遺伝子

マウス[1]  NM_008854
ラット[2]  NM_001100922

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

33381
221492
1281154
1322130
1375229
1375933
1377674
1406653
1545828
1650365
1684878
1706595
1978848
2050683
2108025
2114109
2117608
2155236
2165385
2176601
2369897
2394752
2413024
2500966
2504723
2548572
2722853
2833520
2843813
2874140
3759968
4092695
6262777
7520867
7525582
7566346
7615546
7688126
7706316
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7790358
7822264
7876254
7905001
7929424
7946090
8002936
8027074
8058338
8117614
8132598
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8182057
8226875
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8380342
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8506364
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8626720
8647104
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8663994
8664319
8810272
8816779
8884279
8939981
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9029147
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9030777
9050991
9060639
9091312
9099667
9109552
9115213
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9150141
9151826
9155020
9199504
9213219
9247274
9278385
9341190
9353289
9366517
9374536
9405392
9407077
9417067
9468536
9525956
9540970
9546672
9565682
9639573
9660950
9671211
9677319
9679146
9710607
9722526
9724719
9730685
9735171
9771888
9832145
9837753
9867809
9891036
10051666
10090741
10187789
10228048
10366608
10400690
10441130
10446213
10454575
10559944
10567342
10571231
10576742
10581150
10601328
10604473
10653665
10667577
10698939
10728420
10734119
10737616
10739259
10753751
10805756
10830164
10837251
10837486
10841548
10851246
10874031
10880354
10898738
10906071
10922374
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10969067
10970852
10982398
11027313
11029056
11035810
11039908
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11076968
11104762
11158204
11158305
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11181701
11181841
11278415
11278469
11279195
11283605
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11311121
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11336675
11359875
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11533025
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11751901
11799117
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11834733
11853558
11884598
11895474
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11986331
11997388
11997508
12054501
12082111
12089143
12147701
12154078
12167624
12175859
12196520
12213813
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12237306
12369791
12387894
12392720
12399457
12417592
12435421
12441002
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12475942
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12529267
12534294
12538592
12569367
12574161
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12578970
12589790
12595241
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12628924
12630910
12639913
12654918
12697024
12721358
12773393
12819195
12842892
12851456
12852856
12853467
12917345
12927815
12931191
12938160
12947093
12950172
12954600
12972513
14500710
14530262
14532276
14576165
14597563
14636580
14641008
14701748
14702039
14709557
14724137
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15024086
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15147202
15178447
15212956
15213298
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15489334
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15557340
15569306
15629779
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17895245
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18064650
18178622
18215420
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18299387
18338250
18421013
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18451148
18490653
18505929
18660489
18728186
18836454
18953413
19018281
19100722
19210988
19264843
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19403523
19483721
19573263
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19808666
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20045463
20110267
20133937
20159975
20196770
20209159
20356841
20392842
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21145461
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22750392
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23220172
23245330
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23455922
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23942052
24244405
24344931
24389246
24571724
24578576
24700472
24816145
24855271

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007202  activation of phospholipase C activity
GO:0034199  activation of protein kinase A activity
GO:0007596  blood coagulation
GO:0005975  carbohydrate metabolic process
GO:0071377  cellular response to glucagon stimulus
GO:0071333  cellular response to glucose stimulus
GO:0071374  cellular response to parathyroid hormone stimulus
GO:0051480  cytosolic calcium ion homeostasis
GO:0006112  energy reserve metabolic process
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0000086  G2/M transition of mitotic cell cycle
GO:0006094  gluconeogenesis
GO:0006006  glucose metabolic process
GO:0045087  innate immune response
GO:0001707  mesoderm formation
GO:0000278  mitotic cell cycle
GO:0048011  nerve growth factor receptor signaling pathway
GO:0018105  peptidyl-serine phosphorylation
GO:0071158  positive regulation of cell cycle arrest
GO:0046827  positive regulation of protein export from nucleus
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0007243  protein kinase cascade
GO:0055117  regulation of cardiac muscle contraction
GO:0010881  regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0002027  regulation of heart rate
GO:0050796  regulation of insulin secretion
GO:0045667  regulation of osteoblast differentiation
GO:0043393  regulation of protein binding
GO:0060314  regulation of ryanodine-sensitive calcium-release channel activity
GO:0050804  regulation of synaptic transmission
GO:0007165  signal transduction
GO:0048240  sperm capacitation
GO:0055085  transmembrane transport
GO:0019433  triglyceride catabolic process
GO:0006833  water transport

Cellular Component

GO:0031588  AMP-activated protein kinase complex
GO:0034704  calcium channel complex
GO:0005952  cAMP-dependent protein kinase complex
GO:0005813  centrosome
GO:0005829  cytosol
GO:0016020  membrane
GO:0005739  mitochondrion
GO:0031594  neuromuscular junction
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0004691  cAMP-dependent protein kinase activity
GO:0005515  protein binding
GO:0034237  protein kinase A regulatory subunit binding
GO:0019901  protein kinase binding
GO:0031625  ubiquitin protein ligase binding