protein kinase C, delta

詳細情報を見る

同義遺伝子名

PKC delta, nPKC-delta, Xanthine oxidase (XO), Protein kinase C delta type, PRKCD, MAY1, MGC49908, protein kinase C, delta

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:13 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:122.70 脊柱:- 網膜:- 目:- 動脈:60 静脈:- リンパ節:384.20 末梢血:109.30 脾臓:56.70 胸腺:- 骨髄:196.80 脂肪:40.30 骨:12.80 皮膚:33.60
GeneChip 大脳:5.50 小脳:5.29 脳幹:5.35 脳梁:5.56 松果体:- 末梢神経:6.68 脊柱:5.29 網膜:- 目:- 動脈:5.92 静脈:6.18 リンパ節:6.86 末梢血:- 脾臓:6.82 胸腺:5.87 骨髄:8.03 脂肪:6.86 骨:- 皮膚:6.61
CAGE 大脳:2.40 小脳:- 脳幹:2.51 脳梁:2.79 松果体:1.99 末梢神経:- 脊柱:2.70 網膜:- 目:- 動脈:3.34 静脈:3.69 リンパ節:3.63 末梢血:- 脾臓:3.65 胸腺:2.63 骨髄:- 脂肪:3.76 骨:- 皮膚:-
RNA-seq 大脳:0.38 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.99 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.59 骨:- 皮膚:-
EST 子宮:36.50 胎盤:18.20 前立腺:78.90 卵巣:- 精巣:47.60 心臓:12.80 骨格筋:- 食道:- 胃:- 腸:32.40 結腸:101.80     肝臓:-        肺:63.50    膀胱:- 腎臓:10.40 下垂体:- 甲状腺:- 副腎:50.80 膵臓:44.50 乳腺:92.90 唾液腺:328.40
GeneChip 子宮:5.65 胎盤:5.71 前立腺:7.49 卵巣:6.08 精巣:6.42 心臓:5.61 骨格筋:4.84 食道:6.82 胃:6.27 腸:6.06 結腸:6.54 肝臓:4.97 肺:6.94 膀胱:- 腎臓:6.32 下垂体:5.08 甲状腺:7.14 副腎:7.01 膵臓:5.57 乳腺:6.46 唾液腺:6.07
CAGE 子宮:2.27 胎盤:2.43 前立腺:3.31 卵巣:2.61 精巣:2.88 心臓:2.72 骨格筋:1.45 食道:3.07 胃:- 腸:4.15 結腸:3.80     肝臓:1.90    肺:3.93 膀胱:3.05 腎臓:3.21 下垂体:1.73 甲状腺:3.66 副腎:- 膵臓:2.90 乳腺:3.33 唾液腺:2.35
RNA-seq 子宮:- 胎盤:- 前立腺:1.67 卵巣:0.62 精巣:1.62 心臓:0.47 骨格筋:0.28 食道:- 胃:- 腸:- 結腸:0.69     肝臓:0.00        肺:1.58    膀胱:- 腎臓:1.88 下垂体:- 甲状腺:1.57 副腎:0.17 膵臓:- 乳腺:1.80 唾液腺:-

IDs

Refseq ID NM_006254
Gene ID 5580
Unigene ID Hs.155342
Probe set ID 202545_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000163932
GTEx ID ENSG00000163932

オーソログ対応遺伝子

マウス[1]  NM_011103
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1677563
1694174
1832084
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24500718
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007202  activation of phospholipase C activity
GO:0006915  apoptosis
GO:0015810  aspartate transport
GO:0042100  B cell proliferation
GO:0007596  blood coagulation
GO:0007049  cell cycle
GO:0006921  cell structure disassembly during apoptosis
GO:0042149  cellular response to glucose starvation
GO:0032869  cellular response to insulin stimulus
GO:0032963  collagen metabolic process
GO:0019221  cytokine-mediated signaling pathway
GO:0042742  defense response to bacterium
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0010467  gene expression
GO:0016064  immunoglobulin mediated immune response
GO:0006917  induction of apoptosis
GO:0045087  innate immune response
GO:0060333  interferon-gamma-mediated signaling pathway
GO:0032613  interleukin-10 production
GO:0032615  interleukin-12 production
GO:0016071  mRNA metabolic process
GO:0030837  negative regulation of actin filament polymerization
GO:0051490  negative regulation of filopodium assembly
GO:0034351  negative regulation of glial cell apoptosis
GO:0050728  negative regulation of inflammatory response
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0043407  negative regulation of MAP kinase activity
GO:0050732  negative regulation of peptidyl-tyrosine phosphorylation
GO:0032091  negative regulation of protein binding
GO:0048011  nerve growth factor receptor signaling pathway
GO:0042119  neutrophil activation
GO:0018107  peptidyl-threonine phosphorylation
GO:0030168  platelet activation
GO:0046326  positive regulation of glucose import
GO:0043406  positive regulation of MAP kinase activity
GO:0035307  positive regulation of protein amino acid dephosphorylation
GO:0032930  positive regulation of superoxide release
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0050821  protein stabilization
GO:0010469  regulation of receptor activity
GO:0043200  response to amino acid stimulus
GO:0042493  response to drug
GO:0045471  response to ethanol
GO:0009749  response to glucose stimulus
GO:0009408  response to heat
GO:0042542  response to hydrogen peroxide
GO:0001666  response to hypoxia
GO:0009612  response to mechanical stimulus
GO:0014070  response to organic cyclic substance
GO:0016070  RNA metabolic process
GO:0007165  signal transduction

Cellular Component

GO:0005911  cell-cell junction
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0005739  mitochondrion
GO:0016363  nuclear matrix
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0004699  calcium-independent protein kinase C activity
GO:0008047  enzyme activator activity
GO:0019899  enzyme binding
GO:0043560  insulin receptor substrate binding
GO:0046872  metal ion binding
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0019901  protein kinase binding
GO:0004697  protein kinase C activity
GO:0004674  protein serine/threonine kinase activity
GO:0070976  TIR domain binding