mitogen-activated protein kinase 3

詳細情報を見る

同義遺伝子名

PRKM3, Mitogen-activated protein kinase 3, MAPK 1, Extracellular signal-regulated kinase 1, ERK1, p44erk1, MGC20180, mitogen-activated protein kinase 3, MAPK3, MAP kinase 1, p44mapk, P44MAPK, ERT2, HS44KDAP, Microtubule-associated protein 2 kinase, p44-ERK1, P44ERK1, ERK-1, HUMKER1A, Insulin-stimulated MAP2 kinase, p44-MAPK

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:26.10 小脳:- 脳幹:- 脳梁:- 松果体:445 末梢神経:61.30 脊柱:- 網膜:- 目:70.50 動脈:119.90 静脈:- リンパ節:101.10 末梢血:36.40 脾臓:37.80 胸腺:25.80 骨髄:- 脂肪:- 骨:12.80 皮膚:52.80
GeneChip 大脳:8.05 小脳:7.79 脳幹:7.97 脳梁:7.87 松果体:- 末梢神経:8.43 脊柱:7.98 網膜:- 目:- 動脈:7.82 静脈:7.67 リンパ節:7.69 末梢血:- 脾臓:7.43 胸腺:7.26 骨髄:7.56 脂肪:7.96 骨:- 皮膚:7.77
CAGE 大脳:3.82 小脳:- 脳幹:3.72 脳梁:4.07 松果体:3.15 末梢神経:- 脊柱:3.38 網膜:- 目:- 動脈:3.70 静脈:3.29 リンパ節:3.62 末梢血:- 脾臓:3.45 胸腺:2.67 骨髄:- 脂肪:3.81 骨:- 皮膚:-
RNA-seq 大脳:0.44 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.27 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.23 骨:- 皮膚:-
EST 子宮:9.10 胎盤:72.90 前立腺:11.30 卵巣:37.30 精巣:17.30 心臓:25.50 骨格筋:20.10 食道:342.80 胃:- 腸:- 結腸:17     肝臓:42.20        肺:34.20    膀胱:- 腎臓:41.60 下垂体:- 甲状腺:- 副腎:- 膵臓:35.60 乳腺:18.60 唾液腺:-
GeneChip 子宮:7.59 胎盤:7.51 前立腺:7.38 卵巣:7.68 精巣:7.65 心臓:7.56 骨格筋:7.39 食道:8.25 胃:7.64 腸:7.62 結腸:8.11 肝臓:7.25 肺:7.71 膀胱:- 腎臓:7.57 下垂体:7.74 甲状腺:7.72 副腎:7.54 膵臓:7.71 乳腺:7.67 唾液腺:7.46
CAGE 子宮:3.84 胎盤:3.90 前立腺:3.70 卵巣:3.87 精巣:3.28 心臓:3.41 骨格筋:2.68 食道:3.93 胃:- 腸:4.58 結腸:4.18     肝臓:2.77    肺:3.54 膀胱:3.60 腎臓:3.24 下垂体:2.81 甲状腺:3.41 副腎:- 膵臓:2.60 乳腺:3.40 唾液腺:3.53
RNA-seq 子宮:- 胎盤:- 前立腺:0.52 卵巣:1.30 精巣:0.75 心臓:0.07 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:1.35     肝臓:0.00        肺:0.25    膀胱:- 腎臓:0.04 下垂体:- 甲状腺:0.24 副腎:0.13 膵臓:- 乳腺:0.69 唾液腺:-

IDs

Refseq ID NM_001109891
Gene ID 5595
Unigene ID Hs.86131
Probe set ID 212046_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000102882
GTEx ID ENSG00000102882

オーソログ対応遺伝子

マウス[1]  NM_011952
ラット[1]  NM_011952

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

862676
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0000186  activation of MAPKK activity
GO:0006915  apoptosis
GO:0007411  axon guidance
GO:0007596  blood coagulation
GO:0030509  BMP signaling pathway
GO:0051216  cartilage development
GO:0007049  cell cycle
GO:0071260  cellular response to mechanical stimulus
GO:0019221  cytokine-mediated signaling pathway
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0010467  gene expression
GO:0045087  innate immune response
GO:0008286  insulin receptor signaling pathway
GO:0070498  interleukin-1-mediated signaling pathway
GO:0060397  JAK-STAT cascade involved in growth hormone signaling pathway
GO:0031663  lipopolysaccharide-mediated signaling pathway
GO:0000165  MAPKKK cascade
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0048011  nerve growth factor receptor signaling pathway
GO:0009887  organ morphogenesis
GO:0016310  phosphorylation
GO:0030168  platelet activation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0035066  positive regulation of histone acetylation
GO:0033129  positive regulation of histone phosphorylation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006468  protein amino acid phosphorylation
GO:0007265  Ras protein signal transduction
GO:0051493  regulation of cytoskeleton organization
GO:0090170  regulation of Golgi inheritance
GO:0032872  regulation of stress-activated MAPK cascade
GO:0051090  regulation of transcription factor activity
GO:0006974  response to DNA damage stimulus
GO:0070849  response to epidermal growth factor stimulus
GO:0043330  response to exogenous dsRNA
GO:0019233  sensory perception of pain
GO:0007264  small GTPase mediated signal transduction
GO:0051403  stress-activated MAPK cascade
GO:0034166  toll-like receptor 10 signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034146  toll-like receptor 5 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway
GO:0006360  transcription from RNA polymerase I promoter
GO:0006361  transcription initiation from RNA polymerase I promoter
GO:0019048  virus-host interaction

Cellular Component

GO:0005901  caveola
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0005769  early endosome
GO:0005925  focal adhesion
GO:0005794  Golgi apparatus
GO:0005770  late endosome
GO:0015630  microtubule cytoskeleton
GO:0005739  mitochondrion
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0031143  pseudopodium

Molecular Function

GO:0005524  ATP binding
GO:0004707  MAP kinase activity
GO:0019902  phosphatase binding
GO:0001784  phosphotyrosine binding
GO:0005515  protein binding