mitogen-activated protein kinase 7

同義遺伝子名

MAPK7, ERK4, mitogen-activated protein kinase 7, ERK5, PRKM7, BMK1, BMK1 kinase, ERK-5, Extracellular signal-regulated kinase 5, Mitogen-activated protein kinase 7

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:32

小脳:-

脳幹:-

脳梁:87.50

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:58.80

動脈:-

静脈:-

リンパ節:10.10

末梢血:18.20

脾臓:18.90

胸腺:193.30

骨髄:19.70

脂肪:40.30

骨:51.20

皮膚:19.20

GeneChip

大脳:5.60

小脳:5.79

脳幹:5.52

脳梁:5.69

松果体:-

末梢神経:5.96

脊柱:5.70

網膜:-

目:-

動脈:6.12

静脈:5.95

リンパ節:5.92

末梢血:-

脾臓:5.89

胸腺:5.44

骨髄:5.88

脂肪:6.15

骨:-

皮膚:6

CAGE

大脳:2.03

小脳:-

脳幹:2.23

脳梁:2.40

松果体:2.60

末梢神経:-

脊柱:2.31

網膜:-

目:-

動脈:3.06

静脈:2.66

リンパ節:2.62

末梢血:-

脾臓:2.88

胸腺:1.81

骨髄:-

脂肪:2.79

骨:-

皮膚:-

RNA-seq

大脳:0.31

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:0.63

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.08

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:82

胎盤:10.90

前立腺:11.30

卵巣:74.50

精巣:34.60

心臓:-

骨格筋:-

食道:-

胃:21.20

腸:-

結腸:-

肝臓:-

肺:19.60

膀胱:-

腎臓:20.80

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:9.30

唾液腺:-

GeneChip

子宮:5.86

胎盤:6.06

前立腺:5.50

卵巣:5.62

精巣:6.44

心臓:5.86

骨格筋:5.78

食道:6.20

胃:5.83

腸:6.06

結腸:6.10

肝臓:5.79

肺:6.02

膀胱:-

腎臓:5.88

下垂体:6

甲状腺:5.89

副腎:6.12

膵臓:5.53

乳腺:5.93

唾液腺:5.64

CAGE

子宮:2.92

胎盤:2.76

前立腺:2.98

卵巣:3.48

精巣:3.00

心臓:2.51

骨格筋:2.21

食道:3.02

胃:-

腸:2.71

結腸:2.80

肝臓:1.90

肺:2.63

膀胱:2.85

腎臓:2.67

下垂体:2.37

甲状腺:2.14

副腎:-

膵臓:2.08

乳腺:2.79

唾液腺:2.06

RNA-seq

子宮:-

胎盤:-

前立腺:1.14

卵巣:2.93

精巣:2.13

心臓:0.10

骨格筋:0.57

食道:-

胃:-

腸:-

結腸:1.24

肝臓:0.11

肺:1.64

膀胱:-

腎臓:0.74

下垂体:-

甲状腺:1.42

副腎:1.34

膵臓:-

乳腺:1.00

唾液腺:-

IDs

Refseq ID	NM_002749
Gene ID	5598
Unigene ID	Hs.150136
Probe set ID	207292_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000166484
GTEx ID	ENSG00000166484

オーソログ対応遺伝子

マウス[1]	NM_011841
ラット [0]

染色体

17p11.2 [19,281,034 - 19,286,857]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0019933	cAMP-mediated signaling
GO:0007049	cell cycle
GO:0030154	cell differentiation
GO:0071363	cellular response to growth factor stimulus
GO:0070301	cellular response to hydrogen peroxide
GO:0071499	cellular response to laminar fluid shear stress
GO:0045087	innate immune response
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0002756	MyD88-independent toll-like receptor signaling pathway
GO:0030821	negative regulation of cAMP catabolic process
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity
GO:0034115	negative regulation of heterotypic cell-cell adhesion
GO:0050728	negative regulation of inflammatory response
GO:0051534	negative regulation of NFAT protein import into nucleus
GO:0060761	negative regulation of response to cytokine stimulus
GO:0048011	nerve growth factor receptor signaling pathway
GO:0018105	peptidyl-serine phosphorylation
GO:0051247	positive regulation of protein metabolic process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045765	regulation of angiogenesis
GO:0007165	signal transduction
GO:0051403	stress-activated MAPK cascade
GO:0034166	toll-like receptor 10 signaling pathway
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034138	toll-like receptor 3 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0034146	toll-like receptor 5 signaling pathway
GO:0034162	toll-like receptor 9 signaling pathway
GO:0002224	toll-like receptor signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0016605	PML body

Molecular Function

GO:0005524	ATP binding
GO:0004707	MAP kinase activity
GO:0051019	mitogen-activated protein kinase binding
GO:0005515	protein binding

mitogen-activated protein kinase 7

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function