mitogen-activated protein kinase 7

詳細情報を見る

同義遺伝子名

MAPK7, ERK4, mitogen-activated protein kinase 7, ERK5, PRKM7, BMK1, BMK1 kinase, ERK-5, Extracellular signal-regulated kinase 5, Mitogen-activated protein kinase 7

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:32 小脳:- 脳幹:- 脳梁:87.50 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:58.80 動脈:- 静脈:- リンパ節:10.10 末梢血:18.20 脾臓:18.90 胸腺:193.30 骨髄:19.70 脂肪:40.30 骨:51.20 皮膚:19.20
GeneChip 大脳:5.60 小脳:5.79 脳幹:5.52 脳梁:5.69 松果体:- 末梢神経:5.96 脊柱:5.70 網膜:- 目:- 動脈:6.12 静脈:5.95 リンパ節:5.92 末梢血:- 脾臓:5.89 胸腺:5.44 骨髄:5.88 脂肪:6.15 骨:- 皮膚:6
CAGE 大脳:2.03 小脳:- 脳幹:2.23 脳梁:2.40 松果体:2.60 末梢神経:- 脊柱:2.31 網膜:- 目:- 動脈:3.06 静脈:2.66 リンパ節:2.62 末梢血:- 脾臓:2.88 胸腺:1.81 骨髄:- 脂肪:2.79 骨:- 皮膚:-
RNA-seq 大脳:0.00 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.29 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.28 骨:- 皮膚:-
EST 子宮:82 胎盤:10.90 前立腺:11.30 卵巣:74.50 精巣:34.60 心臓:- 骨格筋:- 食道:- 胃:21.20 腸:- 結腸:-     肝臓:-        肺:19.60    膀胱:- 腎臓:20.80 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:9.30 唾液腺:-
GeneChip 子宮:5.86 胎盤:6.06 前立腺:5.50 卵巣:5.62 精巣:6.44 心臓:5.86 骨格筋:5.78 食道:6.20 胃:5.83 腸:6.06 結腸:6.10 肝臓:5.79 肺:6.02 膀胱:- 腎臓:5.88 下垂体:6 甲状腺:5.89 副腎:6.12 膵臓:5.53 乳腺:5.93 唾液腺:5.64
CAGE 子宮:2.92 胎盤:2.76 前立腺:2.98 卵巣:3.48 精巣:3.00 心臓:2.51 骨格筋:2.21 食道:3.02 胃:- 腸:2.71 結腸:2.80     肝臓:1.90    肺:2.63 膀胱:2.85 腎臓:2.67 下垂体:2.37 甲状腺:2.14 副腎:- 膵臓:2.08 乳腺:2.79 唾液腺:2.06
RNA-seq 子宮:- 胎盤:- 前立腺:0.38 卵巣:0.49 精巣:0.45 心臓:0.18 骨格筋:0.12 食道:- 胃:- 腸:- 結腸:0.67     肝臓:0.08        肺:0    膀胱:- 腎臓:0.00 下垂体:- 甲状腺:0.44 副腎:0.43 膵臓:- 乳腺:0.26 唾液腺:-

IDs

Refseq ID NM_139033
Gene ID 5598
Unigene ID Hs.150136
Probe set ID 207292_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000166484
GTEx ID ENSG00000166484

オーソログ対応遺伝子

マウス[1]  NM_011841
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0019933  cAMP-mediated signaling
GO:0007049  cell cycle
GO:0030154  cell differentiation
GO:0071363  cellular response to growth factor stimulus
GO:0070301  cellular response to hydrogen peroxide
GO:0071499  cellular response to laminar fluid shear stress
GO:0045087  innate immune response
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0030821  negative regulation of cAMP catabolic process
GO:0051344  negative regulation of cyclic-nucleotide phosphodiesterase activity
GO:0034115  negative regulation of heterotypic cell-cell adhesion
GO:0050728  negative regulation of inflammatory response
GO:0051534  negative regulation of NFAT protein import into nucleus
GO:0060761  negative regulation of response to cytokine stimulus
GO:0048011  nerve growth factor receptor signaling pathway
GO:0018105  peptidyl-serine phosphorylation
GO:0051247  positive regulation of protein metabolic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045765  regulation of angiogenesis
GO:0007165  signal transduction
GO:0051403  stress-activated MAPK cascade
GO:0034166  toll-like receptor 10 signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034146  toll-like receptor 5 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0016605  PML body

Molecular Function

GO:0005524  ATP binding
GO:0004707  MAP kinase activity
GO:0051019  mitogen-activated protein kinase binding
GO:0005515  protein binding