BCL2-associated agonist of cell death

詳細情報を見る

同義遺伝子名

BAD, BBC2, BBC6, BCL2-antagonist of cell death, BCL2L8, Bcl-2-like 8 protein, Bcl-2-binding component 6, Bcl2 antagonist of cell death, Bcl-XL/Bcl-2-associated death promoter

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:22.50 小脳:- 脳幹:- 脳梁:- 松果体:445 末梢神経:30.70 脊柱:- 網膜:118.60 目:135.20 動脈:- 静脈:- リンパ節:91 末梢血:- 脾臓:- 胸腺:38.70 骨髄:- 脂肪:- 骨:- 皮膚:24
GeneChip 大脳:6.60 小脳:6.32 脳幹:6.71 脳梁:6.30 松果体:- 末梢神経:6.47 脊柱:6.43 網膜:- 目:- 動脈:6.77 静脈:6.75 リンパ節:6.20 末梢血:- 脾臓:5.95 胸腺:6.25 骨髄:5.87 脂肪:6.49 骨:- 皮膚:6.49
CAGE 大脳:3.03 小脳:- 脳幹:2.79 脳梁:3.06 松果体:2.80 末梢神経:- 脊柱:2.71 網膜:- 目:- 動脈:2.98 静脈:2.69 リンパ節:2.67 末梢血:- 脾臓:2.39 胸腺:2.74 骨髄:- 脂肪:2.60 骨:- 皮膚:-
RNA-seq 大脳:1.16 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.50 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.39 骨:- 皮膚:-
EST 子宮:27.30 胎盤:36.40 前立腺:135.20 卵巣:111.80 精巣:26 心臓:51.10 骨格筋:20.10 食道:- 胃:- 腸:- 結腸:135.70     肝臓:-        肺:58.70    膀胱:- 腎臓:62.40 下垂体:- 甲状腺:- 副腎:50.80 膵臓:26.70 乳腺:9.30 唾液腺:-
GeneChip 子宮:6.44 胎盤:6.32 前立腺:6.85 卵巣:6.44 精巣:6.81 心臓:6.44 骨格筋:6.10 食道:6.63 胃:6.39 腸:6.19 結腸:6.46 肝臓:6.49 肺:6.44 膀胱:- 腎臓:6.74 下垂体:6.36 甲状腺:6.83 副腎:6.53 膵臓:6.01 乳腺:6.49 唾液腺:6.51
CAGE 子宮:2.97 胎盤:3.16 前立腺:3.09 卵巣:2.94 精巣:2.99 心臓:2.97 骨格筋:2.31 食道:2.94 胃:- 腸:2.75 結腸:3.15     肝臓:2.64    肺:2.93 膀胱:2.85 腎臓:2.81 下垂体:2.20 甲状腺:3.28 副腎:- 膵臓:3.02 乳腺:2.99 唾液腺:2.83
RNA-seq 子宮:- 胎盤:- 前立腺:0.26 卵巣:0.58 精巣:1.32 心臓:0.56 骨格筋:0 食道:- 胃:- 腸:- 結腸:0.65     肝臓:0.58        肺:0.10    膀胱:- 腎臓:1.05 下垂体:- 甲状腺:0.54 副腎:0.71 膵臓:- 乳腺:0.42 唾液腺:-

IDs

Refseq ID NM_004322
Gene ID 572
Unigene ID Hs.370254
Probe set ID 209364_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000002330
GTEx ID ENSG00000002330

オーソログ対応遺伝子

マウス[2]  NM_007522
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7834748
8929531
8929532
9130713
9305851
9369453
9381178
9388232
9389483
9463381
9651683
9824152
9878060
9973195
10195903
10381646
10407019
10521512
10558990
10579309
10611223
10620799
10811615
10837486
10837489
10880354
10949025
10949026
11077446
11206074
11278245
11410287
11483855
11494146
11500364
11544290
11583631
11689886
11697890
11717309
11739707
11742726
11781193
11839683
11878929
11908866
11994280
12084714
12087097
12115603
12137781
12239175
12376548
12477932
12657644
12754297
12787561
12842996
12897128
12931191
12954615
12965220
14702039
14767529
14967141
15033904
15078178
15131699
15183529
15226424
15231831
15280438
15489334
15574335
15694340
15705582
15721256
15731037
15751984
15767261
15784622
15849194
15901741
15978696
15990872
15998799
16148027
16189514
16297499
16403219
16413544
16445909
16484005
16603546
16697956
16710454
16728406
16767165
16785131
16843435
16847055
16908594
16932738
16949642
16978419
17011751
17110373
17270021
17274640
17287851
17289999
17393317
17404594
17420275
17438366
17446862
17457084
17474147
17499381
17541305
17544220
17557568
17670745
17696955
17696989
17900801
17927446
17979178
18006502
18029348
18165867
18246127
18276761
18309324
18387192
18391004
18402774
18402937
18420586
18449891
18508762
18508827
18568448
18593990
18628207
18636124
18651163
18651222
18676776
18775810
18798227
18832722
18852119
18973553
19168699
19171933
19508210
19587239
19593445
19624871
19641507
19667065
19679565
19730683
19773546
19882362
19895838
19913121
20012528
20043968
20339252
20596645
20618440
20628086
20647330
20691103
20700721
20810912
20855536
20877624
20936779
21076048
21081150
21187157
21302807
21317286
21419810
21444773
21674599
21849418
21900206
21918885
21988832
22011203
22057915
22096607
22172950
22214866
22423221
22464442
22805310
22837380
23135712
23383273
23547889
23794242
23811558
24040284
24255178
24421315

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0046031  ADP metabolic process
GO:0006915  apoptosis
GO:0046034  ATP metabolic process
GO:0060154  cellular process regulating host cell cycle in response to virus
GO:0071247  cellular response to chromate
GO:0071456  cellular response to hypoxia
GO:0071396  cellular response to lipid
GO:0071260  cellular response to mechanical stimulus
GO:0071316  cellular response to nicotine
GO:0019221  cytokine-mediated signaling pathway
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0006007  glucose catabolic process
GO:0042593  glucose homeostasis
GO:0006917  induction of apoptosis
GO:0045087  innate immune response
GO:0048011  nerve growth factor receptor signaling pathway
GO:0048015  phosphoinositide-mediated signaling
GO:0046931  pore complex assembly
GO:0043065  positive regulation of apoptosis
GO:0010508  positive regulation of autophagy
GO:0045579  positive regulation of B cell differentiation
GO:0043280  positive regulation of caspase activity
GO:0050679  positive regulation of epithelial cell proliferation
GO:0033133  positive regulation of glucokinase activity
GO:0032024  positive regulation of insulin secretion
GO:0010918  positive regulation of mitochondrial membrane potential
GO:0045862  positive regulation of proteolysis
GO:0090200  positive regulation of release of cytochrome c from mitochondria
GO:0045582  positive regulation of T cell differentiation
GO:0046902  regulation of mitochondrial membrane permeability
GO:0043200  response to amino acid stimulus
GO:0051592  response to calcium ion
GO:0042493  response to drug
GO:0032355  response to estradiol stimulus
GO:0045471  response to ethanol
GO:0051384  response to glucocorticoid stimulus
GO:0009749  response to glucose stimulus
GO:0042542  response to hydrogen peroxide
GO:0034201  response to oleic acid
GO:0032570  response to progesterone stimulus
GO:0033574  response to testosterone stimulus

Cellular Component

GO:0005829  cytosol
GO:0005741  mitochondrial outer membrane
GO:0005739  mitochondrion

Molecular Function

GO:0008656  caspase activator activity
GO:0008289  lipid binding
GO:0005543  phospholipid binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0043422  protein kinase B binding
GO:0019901  protein kinase binding
GO:0030346  protein phosphatase 2B binding