patched homolog 1 (Drosophila)

詳細情報を見る

同義遺伝子名

PTCH1, PTC1, NBCCS, patched homolog (Drosophila), Protein patched homolog 1, patched (Drosophila) homolog, FLJ42602, patched homolog 1 (Drosophila), BCNS, HPE7, PTCH

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:3.95 小脳:4.14 脳幹:3.94 脳梁:3.96 松果体:- 末梢神経:4.69 脊柱:3.91 網膜:- 目:- 動脈:3.89 静脈:4.09 リンパ節:3.73 末梢血:- 脾臓:3.73 胸腺:3.53 骨髄:4.13 脂肪:3.85 骨:- 皮膚:3.67
CAGE 大脳:1.95 小脳:- 脳幹:2.14 脳梁:2.26 松果体:1.65 末梢神経:- 脊柱:2.12 網膜:- 目:- 動脈:2.02 静脈:1.23 リンパ節:1.61 末梢血:- 脾臓:1.67 胸腺:0.80 骨髄:- 脂肪:1.12 骨:- 皮膚:-
RNA-seq 大脳:0.32 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.57 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.73 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:4.13 胎盤:3.81 前立腺:3.83 卵巣:3.71 精巣:3.80 心臓:3.90 骨格筋:4.03 食道:3.76 胃:4.28 腸:3.93 結腸:4.27 肝臓:3.85 肺:3.74 膀胱:- 腎臓:3.99 下垂体:3.97 甲状腺:3.83 副腎:4.04 膵臓:4.20 乳腺:3.67 唾液腺:3.86
CAGE 子宮:2.57 胎盤:1.11 前立腺:1.88 卵巣:1.29 精巣:2.70 心臓:1.40 骨格筋:0.95 食道:1.48 胃:- 腸:2.23 結腸:2.92     肝臓:0.78    肺:2.13 膀胱:1.45 腎臓:1.48 下垂体:1.42 甲状腺:1.96 副腎:- 膵臓:2.54 乳腺:2.27 唾液腺:2.43
RNA-seq 子宮:- 胎盤:- 前立腺:0.55 卵巣:0.27 精巣:0.54 心臓:0.57 骨格筋:0 食道:- 胃:- 腸:- 結腸:0.39     肝臓:0.22        肺:0.55    膀胱:- 腎臓:0.57 下垂体:- 甲状腺:1.72 副腎:0.66 膵臓:- 乳腺:0.61 唾液腺:-

IDs

Refseq ID NM_001083606
Gene ID 5727
Unigene ID Hs.638946
Probe set ID 209816_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000185920
GTEx ID ENSG00000185920

オーソログ対応遺伝子

マウス[1]  NM_008957
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007420  brain development
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0071397  cellular response to cholesterol
GO:0009953  dorsal/ventral pattern formation
GO:0030326  embryonic limb morphogenesis
GO:0008544  epidermis development
GO:0042593  glucose homeostasis
GO:0003007  heart morphogenesis
GO:0035137  hindlimb morphogenesis
GO:0043616  keratinocyte proliferation
GO:0035108  limb morphogenesis
GO:0060603  mammary gland duct morphogenesis
GO:0060644  mammary gland epithelial cell differentiation
GO:0051782  negative regulation of cell division
GO:0050680  negative regulation of epithelial cell proliferation
GO:0040015  negative regulation of multicellular organism growth
GO:0045668  negative regulation of osteoblast differentiation
GO:0045879  negative regulation of smoothened signaling pathway
GO:0043433  negative regulation of transcription factor activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0021997  neural plate axis specification
GO:0001843  neural tube closure
GO:0021532  neural tube patterning
GO:0009887  organ morphogenesis
GO:0060037  pharyngeal system development
GO:0010875  positive regulation of cholesterol efflux
GO:0016485  protein processing
GO:0007346  regulation of mitotic cell cycle
GO:0032880  regulation of protein localization
GO:0008589  regulation of smoothened signaling pathway
GO:0010157  response to chlorate
GO:0007224  smoothened signaling pathway
GO:0060831  smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:0021522  spinal cord motor neuron differentiation

Cellular Component

GO:0005901  caveola
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0030496  midbody
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0015485  cholesterol binding
GO:0030332  cyclin binding
GO:0008158  hedgehog receptor activity
GO:0008201  heparin binding
GO:0005113  patched binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0005119  smoothened binding