PTK2 protein tyrosine kinase 2

詳細情報を見る

同義遺伝子名

PTK2 protein tyrosine kinase 2, pp125FAK, FADK 1, PTK2, FAK1, FADK, Focal adhesion kinase 1, FAK, Protein-tyrosine kinase 2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:315.30 小脳:251.90 脳幹:- 脳梁:379.10 松果体:296.70 末梢神経:276 脊柱:112.30 網膜:118.60 目:123.40 動脈:30 静脈:66.60 リンパ節:111.20 末梢血:18.20 脾臓:56.70 胸腺:116 骨髄:78.70 脂肪:121 骨:102.40 皮膚:297.60
GeneChip 大脳:7.28 小脳:6.73 脳幹:7.18 脳梁:7.96 松果体:- 末梢神経:6.62 脊柱:7.34 網膜:- 目:- 動脈:6.52 静脈:6.47 リンパ節:6.02 末梢血:- 脾臓:6.10 胸腺:5.80 骨髄:5.92 脂肪:6.47 骨:- 皮膚:5.98
CAGE 大脳:4.61 小脳:- 脳幹:4.75 脳梁:5.18 松果体:4.22 末梢神経:- 脊柱:4.59 網膜:- 目:- 動脈:4.49 静脈:3.78 リンパ節:3.16 末梢血:- 脾臓:3.20 胸腺:2.28 骨髄:- 脂肪:4.00 骨:- 皮膚:-
RNA-seq 大脳:3.76 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.38 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:4.17 骨:- 皮膚:-
EST 子宮:109.40 胎盤:163.90 前立腺:101.40 卵巣:708 精巣:255.30 心臓:191.60 骨格筋:20.10 食道:- 胃:148.70 腸:97.20 結腸:483.30     肝臓:126.70        肺:195.50    膀胱:- 腎臓:104 下垂体:232 甲状腺:163.70 副腎:152.40 膵臓:142.30 乳腺:297.40 唾液腺:-
GeneChip 子宮:6.80 胎盤:7.10 前立腺:6.60 卵巣:6.62 精巣:6.79 心臓:6.61 骨格筋:6.35 食道:6.12 胃:6.58 腸:6.63 結腸:6.58 肝臓:6.28 肺:6.42 膀胱:- 腎臓:6.43 下垂体:6.05 甲状腺:6.17 副腎:6.17 膵臓:6.96 乳腺:6.44 唾液腺:6.52
CAGE 子宮:4.13 胎盤:4.11 前立腺:3.71 卵巣:3.61 精巣:4.03 心臓:3.90 骨格筋:3.47 食道:3.52 胃:- 腸:3.78 結腸:3.92     肝臓:3.21    肺:3.88 膀胱:3.87 腎臓:3.75 下垂体:3.82 甲状腺:3.64 副腎:- 膵臓:3.84 乳腺:4.18 唾液腺:3.89
RNA-seq 子宮:- 胎盤:- 前立腺:4.58 卵巣:4.42 精巣:4.71 心臓:3.62 骨格筋:4.09 食道:- 胃:- 腸:- 結腸:4.50     肝臓:2.62        肺:4.58    膀胱:- 腎臓:3.94 下垂体:- 甲状腺:4.27 副腎:2.61 膵臓:- 乳腺:2.95 唾液腺:-

IDs

Refseq ID NM_153831
Gene ID 5747
Unigene ID Hs.395482
Probe set ID 207821_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000169398
GTEx ID ENSG00000169398

オーソログ対応遺伝子

マウス[3]  NM_001130409, NM_007982
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

7479864
7509446
7515480
7529872
7529876
7537275
7589239
7597091
7622520
7692878
7744883
7766995
7997267
8054685
8247543
8422239
8493579
8609175
8649368
8649427
8654393
8660853
8668148
8770310
8810278
8816475
8879209
8922390
8941336
8986614
9054445
9079653
9148935
9169439
9230116
9257837
9325343
9342235
9360968
9360983
9418872
9422762
9442086
9461600
9497381
9507031
9553131
9636140
9642276
9658172
9708406
9750131
9756887
9786953
9822703
9837978
9858471
9867854
10048580
10082579
10085298
10330411
10384144
10400703
10430888
10446223
10455189
10512882
10526262
10545505
10587647
10655584
10753828
10769033
10801330
10806474
10808124
10822899
10873094
10925297
10931187
10938112
10980697
11113628
11160818
11278329
11278335
11278462
11278857
11314030
11331870
11337490
11359909
11369769
11382919
11389892
11463817
11468295
11476890
11496289
11513739
11514617
11577104
11602246
11668182
11779709
11799111
11807823
11809746
11839772
11857088
11886520
11891225
11916084
11919182
11927607
11950595
11980671
11986332
11988077
12005431
12011046
12023386
12049193
12054581
12058076
12110680
12119061
12135674
12149262
12167618
12169389
12174366
12215217
12216109
12226752
12242727
12297287
12370821
12376862
12387730
12435390
12473661
12477932
12529399
12531888
12543870
12551902
12558988
12611892
12615911
12629171
12651906
12659633
12700132
12748169
12771190
12794117
12803239
12815062
12844492
12847914
12881299
12884911
12904305
12907754
12939401
12954625
14500712
14521607
14553943
14578863
14584897
14617636
14637150
14670178
14688263
14699482
14702039
15077193
15102689
15102844
15121855
15155793
15157737
15161045
15166238
15175910
15210734
15247219
15331608
15369772
15455382
15494732
15494733
15528360
15532706
15557280
15611137
15640164
15652490
15657578
15657875
15673687
15681841
15717329
15725728
15736429
15743500
15778501
15850774
15855171
15866427
15895076
15951569
15975092
16007195
16039608
16054026
16105876
16136050
16141199
16153436
16159962
16189514
16202977
16226872
16244766
16247468
16251422
16260653
16270396
16291744
16298995
16308318
16344560
16354697
16371650
16406804
16412380
16452200
16523241
16581250
16620772
16638855
16705171
16760434
16803572
16842883
16899713
16912186
16919435
16920698
16927379
16998832
17028776
17043358
17081517
17081983
17088251
17096371
17113264
17192257
17213807
17215324
17236584
17240116
17274640
17317726
17327229
17332925
17397984
17443665
17469136
17514628
17515959
17537730
17620332
17675501
17828307
17868650
17879163
17888894
17893324
17904248
17967873
17982280
17999388
18029348
18031698
18032789
18061419
18073135
18078823
18078954
18086875
18182379
18184462
18198129
18206965
18210145
18215142
18223254
18247360
18256281
18263593
18292575
18292781
18322799
18332144
18341635
18349846
18353772
18414015
18449907
18452580
18493017
18497331
18519756
18549812
18562041
18593949
18632638
18669633
18680726
18695939
18713744
18832579
18846341
18922979
18948272
18987997
19006177
19020730
19021002
19029090
19032871
19042019
19055942
19082453
19089993
19098120
19118217
19141860
19147981
19150878
19199036
19242756
19268501
19297531
19297850
19301259
19303400
19318351
19322201
19339212
19364917
19403028
19423701
19435801
19454363
19471549
19473962
19475568
19479902
19481075
19492042
19500106
19525103
19545541
19561089
19563023
19574423
19615356
19633364
19635908
19644410
19656390
19664602
19671193
19695571
19695682
19736351
19737461
19787193
19798549
19823058
19826415
19857493
19889638
19889958
19917775
19931244
20018849
20041213
20056178
20089932
20109444
20124721
20127254
20140743
20145126
20145416
20150423
20151150
20160475
20177740
20191563
20198306
20201928
20233709
20378826
20389021
20400979
20405349
20407018
20431421
20434207
20441998
20515733
20561409
20576130
20594998
20597513
20621036
20725143
20802513
20811717
20869705
20869748
20880986
20924071
20936779
20953136
20959405
20966971
21029396
21042764
21045155
21058027
21068464
21071137
21084629
21127007
21139048
21209368
21247411
21269758
21276823
21281808
21338601
21350188
21383007
21401419
21403855
21411625
21418517
21454615
21454698
21483099
21502966
21590355
21590492
21637765
21643014
21646305
21653826
21656515
21667138
21669400
21693107
21703394
21707507
21716326
21720547
21726809
21765932
21800286
21832049
21852242
21855630
21868344
21875461
21876001
21898412
21900206
21900245
21914806
21921419
21937583
21948112
21967109
21969470
21969587
21988832
21994943
22005766
22009484
22028271
22040413
22075845
22094095
22095445
22149168
22188814
22203669
22203672
22270917
22323655
22336124
22341464
22362758
22378044
22393238
22402131
22402981
22454420
22473839
22481092
22488171
22492165
22493428
22544741
22563076
22733437
22734001
22760257
22766276
22778269
22790665
22810307
22813850
22817694
22854047
22871469
22894899
22898813
22934705
22934707
22934708
22937161
22939624
23022044
23047954
23064287
23077174
23079702
23143646
23179791
23186335
23208492
23209645
23211542
23219295
23232649
23273897
23275034
23328701
23328812
23393139
23499373
23512980
23525457
23536552
23588386
23600470
23602568
23637231
23639457
23689132
23762317
23845472
23906871
23920124
24005669
24015220
24021281
24040310
24058594
24062525
24091658
24092571
24114522
24217252
24222685
24227778
24250222
24344130
24360952
24365239
24370784
24480479
24639526
24657306

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0006915  apoptosis
GO:0007411  axon guidance
GO:0007596  blood coagulation
GO:0048870  cell motility
GO:0006921  cell structure disassembly during apoptosis
GO:0030644  cellular chloride ion homeostasis
GO:0021955  central nervous system neuron axonogenesis
GO:0009790  embryonic development
GO:0043542  endothelial cell migration
GO:0048013  ephrin receptor signaling pathway
GO:0030010  establishment of cell polarity
GO:0040023  establishment of nucleus localization
GO:0030198  extracellular matrix organization
GO:0045444  fat cell differentiation
GO:0060396  growth hormone receptor signaling pathway
GO:0003007  heart morphogenesis
GO:0045087  innate immune response
GO:0007229  integrin-mediated signaling pathway
GO:0007254  JNK cascade
GO:0000226  microtubule cytoskeleton organization
GO:0043066  negative regulation of apoptosis
GO:0050771  negative regulation of axonogenesis
GO:0030336  negative regulation of cell migration
GO:0022408  negative regulation of cell-cell adhesion
GO:0046621  negative regulation of organ growth
GO:0051964  negative regulation of synaptogenesis
GO:0001764  neuron migration
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0001890  placenta development
GO:0030168  platelet activation
GO:0045785  positive regulation of cell adhesion
GO:0030307  positive regulation of cell growth
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0060252  positive regulation of glial cell proliferation
GO:0050766  positive regulation of phagocytosis
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045860  positive regulation of protein kinase activity
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0014911  positive regulation of smooth muscle cell migration
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0050806  positive regulation of synaptic transmission
GO:0045909  positive regulation of vasodilation
GO:0046777  protein amino acid autophosphorylation
GO:0033628  regulation of cell adhesion mediated by integrin
GO:0042127  regulation of cell proliferation
GO:0008360  regulation of cell shape
GO:0051493  regulation of cytoskeleton organization
GO:0010594  regulation of endothelial cell migration
GO:0051893  regulation of focal adhesion formation
GO:0045667  regulation of osteoblast differentiation
GO:0032319  regulation of Rho GTPase activity
GO:0046685  response to arsenic
GO:0042493  response to drug
GO:0032355  response to estradiol stimulus
GO:0009749  response to glucose stimulus
GO:0009612  response to mechanical stimulus
GO:0007172  signal complex assembly
GO:0001570  vasculogenesis

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0005938  cell cortex
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0005925  focal adhesion
GO:0014704  intercalated disc
GO:0030027  lamellipodium
GO:0005815  microtubule organizing center
GO:0016604  nuclear body
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0042383  sarcolemma

Molecular Function

GO:0003779  actin binding
GO:0005524  ATP binding
GO:0005178  integrin binding
GO:0008432  JUN kinase binding
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0043548  phosphoinositide 3-kinase binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0019901  protein kinase binding
GO:0042169  SH2 domain binding
GO:0004871  signal transducer activity