PTK2 protein tyrosine kinase 2

同義遺伝子名

PTK2 protein tyrosine kinase 2, pp125FAK, FADK 1, PTK2, FAK1, FADK, Focal adhesion kinase 1, FAK, Protein-tyrosine kinase 2

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:315.30

小脳:251.90

脳幹:-

脳梁:379.10

松果体:296.70

末梢神経:276

脊柱:112.30

網膜:118.60

目:123.40

動脈:30

静脈:66.60

リンパ節:111.20

末梢血:18.20

脾臓:56.70

胸腺:116

骨髄:78.70

脂肪:121

骨:102.40

皮膚:297.60

GeneChip

大脳:8.48

小脳:7.45

脳幹:8.43

脳梁:9.21

松果体:-

末梢神経:7.45

脊柱:8.41

網膜:-

目:-

動脈:8.01

静脈:8

リンパ節:6.84

末梢血:-

脾臓:6.89

胸腺:5.58

骨髄:5.14

脂肪:7.52

骨:-

皮膚:6.94

CAGE

大脳:4.61

小脳:-

脳幹:4.75

脳梁:5.18

松果体:4.22

末梢神経:-

脊柱:4.59

網膜:-

目:-

動脈:4.49

静脈:3.78

リンパ節:3.16

末梢血:-

脾臓:3.20

胸腺:2.28

骨髄:-

脂肪:4.00

骨:-

皮膚:-

RNA-seq

大脳:3.76

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:3.38

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:4.17

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:109.40

胎盤:163.90

前立腺:101.40

卵巣:708

精巣:255.30

心臓:191.60

骨格筋:20.10

食道:-

胃:148.70

腸:97.20

結腸:483.30

肝臓:126.70

肺:195.50

膀胱:-

腎臓:104

下垂体:232

甲状腺:163.70

副腎:152.40

膵臓:142.30

乳腺:297.40

唾液腺:-

GeneChip

子宮:7.77

胎盤:7.84

前立腺:7.92

卵巣:7.70

精巣:7.94

心臓:7.35

骨格筋:6.91

食道:6.75

胃:7.37

腸:7.37

結腸:7.09

肝臓:6.69

肺:7.61

膀胱:-

腎臓:7.57

下垂体:6.63

甲状腺:7.75

副腎:7.71

膵臓:6.51

乳腺:7.59

唾液腺:7.57

CAGE

子宮:4.13

胎盤:4.11

前立腺:3.71

卵巣:3.61

精巣:4.03

心臓:3.90

骨格筋:3.47

食道:3.52

胃:-

腸:3.78

結腸:3.92

肝臓:3.21

肺:3.88

膀胱:3.87

腎臓:3.75

下垂体:3.82

甲状腺:3.64

副腎:-

膵臓:3.84

乳腺:4.18

唾液腺:3.89

RNA-seq

子宮:-

胎盤:-

前立腺:4.58

卵巣:4.42

精巣:4.71

心臓:3.62

骨格筋:4.09

食道:-

胃:-

腸:-

結腸:4.50

肝臓:2.62

肺:4.58

膀胱:-

腎臓:3.94

下垂体:-

甲状腺:4.27

副腎:2.61

膵臓:-

乳腺:2.95

唾液腺:-

IDs

Refseq ID	NM_153831
Gene ID	5747
Unigene ID	Hs.395482
Probe set ID	208820_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000169398
GTEx ID	ENSG00000169398

オーソログ対応遺伝子

マウス[3]	NM_001130409, NM_007982
ラット [0]

染色体

8q24.3 [141,667,999 - 142,012,315]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR019749	Band 4.1 domain
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0006915	apoptosis
GO:0007411	axon guidance
GO:0007596	blood coagulation
GO:0048870	cell motility
GO:0006921	cell structure disassembly during apoptosis
GO:0030644	cellular chloride ion homeostasis
GO:0021955	central nervous system neuron axonogenesis
GO:0009790	embryonic development
GO:0043542	endothelial cell migration
GO:0048013	ephrin receptor signaling pathway
GO:0030010	establishment of cell polarity
GO:0040023	establishment of nucleus localization
GO:0030198	extracellular matrix organization
GO:0045444	fat cell differentiation
GO:0060396	growth hormone receptor signaling pathway
GO:0003007	heart morphogenesis
GO:0045087	innate immune response
GO:0007229	integrin-mediated signaling pathway
GO:0007254	JNK cascade
GO:0000226	microtubule cytoskeleton organization
GO:0043066	negative regulation of apoptosis
GO:0050771	negative regulation of axonogenesis
GO:0030336	negative regulation of cell migration
GO:0022408	negative regulation of cell-cell adhesion
GO:0046621	negative regulation of organ growth
GO:0051964	negative regulation of synaptogenesis
GO:0001764	neuron migration
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0001890	placenta development
GO:0030168	platelet activation
GO:0045785	positive regulation of cell adhesion
GO:0030307	positive regulation of cell growth
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0060252	positive regulation of glial cell proliferation
GO:0050766	positive regulation of phagocytosis
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0045860	positive regulation of protein kinase activity
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0014911	positive regulation of smooth muscle cell migration
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0050806	positive regulation of synaptic transmission
GO:0045909	positive regulation of vasodilation
GO:0046777	protein amino acid autophosphorylation
GO:0033628	regulation of cell adhesion mediated by integrin
GO:0042127	regulation of cell proliferation
GO:0008360	regulation of cell shape
GO:0051493	regulation of cytoskeleton organization
GO:0010594	regulation of endothelial cell migration
GO:0051893	regulation of focal adhesion formation
GO:0045667	regulation of osteoblast differentiation
GO:0032319	regulation of Rho GTPase activity
GO:0046685	response to arsenic
GO:0042493	response to drug
GO:0032355	response to estradiol stimulus
GO:0009749	response to glucose stimulus
GO:0009612	response to mechanical stimulus
GO:0007172	signal complex assembly
GO:0001570	vasculogenesis

Cellular Component

GO:0016324	apical plasma membrane
GO:0016323	basolateral plasma membrane
GO:0005938	cell cortex
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005829	cytosol
GO:0005925	focal adhesion
GO:0014704	intercalated disc
GO:0030027	lamellipodium
GO:0005815	microtubule organizing center
GO:0016604	nuclear body
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0042383	sarcolemma

Molecular Function

GO:0003779	actin binding
GO:0005524	ATP binding
GO:0005178	integrin binding
GO:0008432	JUN kinase binding
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0043548	phosphoinositide 3-kinase binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0019901	protein kinase binding
GO:0042169	SH2 domain binding
GO:0004871	signal transducer activity

PTK2 protein tyrosine kinase 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function