protein tyrosine phosphatase, non-receptor type 2

詳細情報を見る

同義遺伝子名

TCELLPTP, TCPTP, protein tyrosine phosphatase, non-receptor type 2, Tyrosine-protein phosphatase non-receptor type 2, TC-PTP, PTPT, PTPN2, T-cell protein-tyrosine phosphatase

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:2.66 小脳:2.96 脳幹:2.62 脳梁:2.72 松果体:- 末梢神経:2.57 脊柱:2.61 網膜:- 目:- 動脈:2.57 静脈:2.64 リンパ節:2.85 末梢血:- 脾臓:3.04 胸腺:5.99 骨髄:2.81 脂肪:2.53 骨:- 皮膚:2.59
CAGE 大脳:3.31 小脳:- 脳幹:3.10 脳梁:2.75 松果体:3.97 末梢神経:- 脊柱:4.04 網膜:- 目:- 動脈:3.23 静脈:3.96 リンパ節:3.88 末梢血:- 脾臓:3.84 胸腺:4.64 骨髄:- 脂肪:3.25 骨:- 皮膚:-
RNA-seq 大脳:1.43 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.11 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.76 骨:- 皮膚:-
EST nodata
GeneChip 子宮:2.77 胎盤:2.62 前立腺:2.81 卵巣:2.74 精巣:2.64 心臓:2.56 骨格筋:2.56 食道:2.60 胃:2.62 腸:2.62 結腸:2.62 肝臓:2.77 肺:2.78 膀胱:- 腎臓:2.62 下垂体:2.76 甲状腺:2.76 副腎:2.63 膵臓:2.56 乳腺:2.68 唾液腺:2.54
CAGE 子宮:3.02 胎盤:3.21 前立腺:3.23 卵巣:3.33 精巣:3.00 心臓:3.28 骨格筋:2.91 食道:2.93 胃:- 腸:3.17 結腸:3.11     肝臓:3.49    肺:3.68 膀胱:3.31 腎臓:2.93 下垂体:3.89 甲状腺:3.11 副腎:- 膵臓:3.59 乳腺:3.75 唾液腺:2.95
RNA-seq 子宮:- 胎盤:- 前立腺:1.10 卵巣:1.82 精巣:1.82 心臓:0.68 骨格筋:0.18 食道:- 胃:- 腸:- 結腸:0.64     肝臓:1.30        肺:1.57    膀胱:- 腎臓:1.58 下垂体:- 甲状腺:1.82 副腎:1.93 膵臓:- 乳腺:1.06 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030183  B cell differentiation
GO:0019221  cytokine-mediated signaling pathway
GO:0030218  erythrocyte differentiation
GO:0042593  glucose homeostasis
GO:0008286  insulin receptor signaling pathway
GO:0060333  interferon-gamma-mediated signaling pathway
GO:0008285  negative regulation of cell proliferation
GO:0050922  negative regulation of chemotaxis
GO:0042059  negative regulation of epidermal growth factor receptor signaling pathway
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0050728  negative regulation of inflammatory response
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0060336  negative regulation of interferon-gamma-mediated signaling pathway
GO:0070104  negative regulation of interleukin-6-mediated signaling pathway
GO:0010888  negative regulation of lipid storage
GO:0045650  negative regulation of macrophage differentiation
GO:0050860  negative regulation of T cell receptor signaling pathway
GO:0010804  negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0060339  negative regulation of type I interferon-mediated signaling pathway
GO:0042512  negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518  negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0042524  negative regulation of tyrosine phosphorylation of Stat5 protein
GO:0042527  negative regulation of tyrosine phosphorylation of Stat6 protein
GO:0045722  positive regulation of gluconeogenesis
GO:0060334  regulation of interferon-gamma-mediated signaling pathway
GO:0030217  T cell differentiation

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0005793  ER-Golgi intermediate compartment
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005178  integrin binding
GO:0004726  non-membrane spanning protein tyrosine phosphatase activity
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0004725  protein tyrosine phosphatase activity
GO:0030971  receptor tyrosine kinase binding
GO:0019905  syntaxin binding