v-raf-1 murine leukemia viral oncogene homolog 1

詳細情報を見る

同義遺伝子名

C-RAF, cRaf, Raf-1, RAF1, c-Raf, CRAF, RAF, RAF proto-oncogene serine/threonine-protein kinase, v-raf-1 murine leukemia viral oncogene homolog 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:115 小脳:201.50 脳幹:- 脳梁:233.30 松果体:741.70 末梢神経:214.70 脊柱:224.60 網膜:- 目:129.30 動脈:89.90 静脈:66.60 リンパ節:121.30 末梢血:200.40 脾臓:18.90 胸腺:412.30 骨髄:137.80 脂肪:80.70 骨:115.20 皮膚:144
GeneChip 大脳:6.98 小脳:7.98 脳幹:6.87 脳梁:7.50 松果体:- 末梢神経:7.48 脊柱:7.23 網膜:- 目:- 動脈:8.04 静脈:7.92 リンパ節:7.98 末梢血:- 脾臓:8.14 胸腺:8.32 骨髄:8.29 脂肪:7.72 骨:- 皮膚:8.17
CAGE 大脳:3.54 小脳:- 脳幹:3.44 脳梁:3.82 松果体:3.75 末梢神経:- 脊柱:3.49 網膜:- 目:- 動脈:3.96 静脈:3.51 リンパ節:3.73 末梢血:- 脾臓:3.74 胸腺:3.88 骨髄:- 脂肪:3.78 骨:- 皮膚:-
RNA-seq 大脳:3.55 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.79 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:4.30 骨:- 皮膚:-
EST 子宮:54.70 胎盤:149.40 前立腺:33.80 卵巣:- 精巣:116.80 心臓:242.70 骨格筋:120.50 食道:- 胃:85 腸:64.80 結腸:118.70     肝臓:84.40        肺:195.50    膀胱:- 腎臓:41.60 下垂体:116 甲状腺:163.70 副腎:50.80 膵臓:133.40 乳腺:74.30 唾液腺:-
GeneChip 子宮:8.03 胎盤:7.88 前立腺:8.10 卵巣:8.20 精巣:7.57 心臓:8.26 骨格筋:8.97 食道:8.28 胃:7.89 腸:7.89 結腸:7.58 肝臓:8.13 肺:8.04 膀胱:- 腎臓:7.94 下垂体:7.16 甲状腺:8.23 副腎:7.43 膵臓:6.96 乳腺:8.17 唾液腺:7.61
CAGE 子宮:3.95 胎盤:3.86 前立腺:3.71 卵巣:3.82 精巣:3.64 心臓:3.98 骨格筋:4.39 食道:3.84 胃:- 腸:4.08 結腸:3.84     肝臓:4.14    肺:3.61 膀胱:3.76 腎臓:3.78 下垂体:3.64 甲状腺:3.96 副腎:- 膵臓:4.09 乳腺:3.58 唾液腺:3.77
RNA-seq 子宮:- 胎盤:- 前立腺:5.09 卵巣:4.90 精巣:4.48 心臓:5.32 骨格筋:5.94 食道:- 胃:- 腸:- 結腸:4.21     肝臓:4.72        肺:4.68    膀胱:- 腎臓:4.71 下垂体:- 甲状腺:5.78 副腎:4.75 膵臓:- 乳腺:4.40 唾液腺:-

IDs

Refseq ID NM_002880
Gene ID 5894
Unigene ID Hs.159130
Probe set ID 201244_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000132155
GTEx ID ENSG00000132155

オーソログ対応遺伝子

マウス[2]  NM_029780
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007190  activation of adenylate cyclase activity
GO:0000186  activation of MAPKK activity
GO:0006915  apoptosis
GO:0007411  axon guidance
GO:0007596  blood coagulation
GO:0008283  cell proliferation
GO:0007010  cytoskeleton organization
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0007507  heart development
GO:0045087  innate immune response
GO:0008286  insulin receptor signaling pathway
GO:0034220  ion transmembrane transport
GO:0000165  MAPKKK cascade
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0008285  negative regulation of cell proliferation
GO:0031333  negative regulation of protein complex assembly
GO:0048011  nerve growth factor receptor signaling pathway
GO:0030168  platelet activation
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0007265  Ras protein signal transduction
GO:0042981  regulation of apoptosis
GO:0045595  regulation of cell differentiation
GO:0035023  regulation of Rho protein signal transduction
GO:0001666  response to hypoxia
GO:0007165  signal transduction
GO:0007264  small GTPase mediated signal transduction
GO:0007268  synaptic transmission
GO:0055085  transmembrane transport
GO:0042060  wound healing

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005741  mitochondrial outer membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0031143  pseudopodium

Molecular Function

GO:0005524  ATP binding
GO:0042802  identical protein binding
GO:0004709  MAP kinase kinase kinase activity
GO:0046872  metal ion binding
GO:0031434  mitogen-activated protein kinase kinase binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0017016  Ras GTPase binding