chemokine (C-C motif) ligand 2

同義遺伝子名

SMC-CF, Monocyte secretory protein JE, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, MCAF, HSMCR30, GDCF-2, CCL2, SCYA2, MCP1, HC11, MGC9434, chemokine (C-C motif) ligand 2, Monocyte chemotactic and activating factor, Small inducible cytokine A2 precursor, MCP-1, GDCF-2 HC11

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:4.70

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:88.20

動脈:30

静脈:66.60

リンパ節:131.40

末梢血:54.70

脾臓:-

胸腺:-

骨髄:-

脂肪:40.30

骨:25.60

皮膚:67.20

GeneChip

大脳:5.21

小脳:4.99

脳幹:5.33

脳梁:5.90

松果体:-

末梢神経:7.36

脊柱:8.12

網膜:-

目:-

動脈:8.72

静脈:10.45

リンパ節:6.97

末梢血:-

脾臓:6.13

胸腺:6.22

骨髄:5.43

脂肪:8.33

骨:-

皮膚:6.87

CAGE

大脳:3.87

小脳:-

脳幹:4.30

脳梁:4.87

松果体:2.76

末梢神経:-

脊柱:6.17

網膜:-

目:-

動脈:5.34

静脈:3.96

リンパ節:4.17

末梢血:-

脾臓:4.17

胸腺:2.97

骨髄:-

脂肪:4.55

骨:-

皮膚:-

RNA-seq

大脳:5.66

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:5.47

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.89

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:18.20

胎盤:58.30

前立腺:22.50

卵巣:-

精巣:13

心臓:51.10

骨格筋:-

食道:-

胃:-

腸:64.80

結腸:42.40

肝臓:-

肺:68.40

膀胱:125.60

腎臓:104

下垂体:-

甲状腺:-

副腎:101.60

膵臓:204.50

乳腺:-

唾液腺:-

GeneChip

子宮:6.48

胎盤:6.84

前立腺:8.06

卵巣:6.55

精巣:5.03

心臓:7.89

骨格筋:5.49

食道:6.24

胃:7.46

腸:7.62

結腸:7.53

肝臓:6.01

肺:10.23

膀胱:-

腎臓:6.77

下垂体:5.66

甲状腺:6.88

副腎:7.91

膵臓:5.72

乳腺:7.04

唾液腺:5.85

CAGE

子宮:3.75

胎盤:4.54

前立腺:5.29

卵巣:4.85

精巣:2.72

心臓:5.40

骨格筋:2.84

食道:4.19

胃:-

腸:4.29

結腸:3.44

肝臓:3.79

肺:5.39

膀胱:4.26

腎臓:4.94

下垂体:3.54

甲状腺:3.75

副腎:-

膵臓:3.78

乳腺:3.89

唾液腺:3.24

RNA-seq

子宮:-

胎盤:-

前立腺:5.60

卵巣:5.15

精巣:3.73

心臓:3.86

骨格筋:3.74

食道:-

胃:-

腸:-

結腸:4.26

肝臓:3.08

肺:8.97

膀胱:-

腎臓:4.98

下垂体:-

甲状腺:2.97

副腎:6.95

膵臓:-

乳腺:4.85

唾液腺:-

IDs

Refseq ID	NM_002982
Gene ID	6347
Unigene ID	Hs.303649
Probe set ID	216598_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000108691
GTEx ID	ENSG00000108691

オーソログ対応遺伝子

マウス[1]	NM_011333
ラット [0]

遺伝子オントロジー (GO ID)

Biological Process

GO:0006987	activation of signaling protein activity involved in unfolded protein response
GO:0007568	aging
GO:0001525	angiogenesis
GO:0043615	astrocyte cell migration
GO:0007155	cell adhesion
GO:0007166	cell surface receptor linked signal transduction
GO:0006874	cellular calcium ion homeostasis
GO:0019725	cellular homeostasis
GO:0044267	cellular protein metabolic process
GO:0071346	cellular response to interferon-gamma
GO:0071347	cellular response to interleukin-1
GO:0071222	cellular response to lipopolysaccharide
GO:0071407	cellular response to organic cyclic substance
GO:0071356	cellular response to tumor necrosis factor
GO:0070098	chemokine-mediated signaling pathway
GO:0006935	chemotaxis
GO:0019221	cytokine-mediated signaling pathway
GO:0007010	cytoskeleton organization
GO:0030968	endoplasmic reticulum unfolded protein response
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger
GO:0006959	humoral immune response
GO:0006954	inflammatory response
GO:0007259	JAK-STAT cascade
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0048247	lymphocyte chemotaxis
GO:0048246	macrophage chemotaxis
GO:0000165	MAPKKK cascade
GO:0060137	maternal process involved in parturition
GO:0002548	monocyte chemotaxis
GO:0016525	negative regulation of angiogenesis
GO:0034351	negative regulation of glial cell apoptosis
GO:0043524	negative regulation of neuron apoptosis
GO:0030593	neutrophil chemotaxis
GO:0009887	organ morphogenesis
GO:0031100	organ regeneration
GO:0001938	positive regulation of endothelial cell proliferation
GO:0010759	positive regulation of macrophage chemotaxis
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process
GO:0050806	positive regulation of synaptic transmission
GO:0050870	positive regulation of T cell activation
GO:0006468	protein amino acid phosphorylation
GO:0043491	protein kinase B signaling cascade
GO:0008360	regulation of cell shape
GO:0010574	regulation of vascular endothelial growth factor production
GO:0014823	response to activity
GO:0043200	response to amino acid stimulus
GO:0046677	response to antibiotic
GO:0009617	response to bacterium
GO:0042493	response to drug
GO:0045471	response to ethanol
GO:0010332	response to gamma radiation
GO:0051384	response to glucocorticoid stimulus
GO:0009408	response to heat
GO:0001666	response to hypoxia
GO:0009612	response to mechanical stimulus
GO:0032570	response to progesterone stimulus
GO:0033552	response to vitamin B3
GO:0007165	signal transduction
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0048010	vascular endothelial growth factor receptor signaling pathway
GO:0019079	viral genome replication

Cellular Component

GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005615	extracellular space

Molecular Function

GO:0031727	CCR2 chemokine receptor binding
GO:0008009	chemokine activity
GO:0008201	heparin binding
GO:0004672	protein kinase activity
GO:0005102	receptor binding

chemokine (C-C motif) ligand 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function