secreted frizzled-related protein 1

詳細情報を見る

同義遺伝子名

FRP1, FrzA, FRP-1, Secreted frizzled-related protein 1 precursor, Frizzled-related protein 1, SARP-2, secreted frizzled-related protein 1, SFRP1, sFRP-1, SARP2, Secreted apoptosis-related protein 2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:6.20 小脳:7.50 脳幹:6.17 脳梁:7.26 松果体:- 末梢神経:7.14 脊柱:5.69 網膜:- 目:- 動脈:8.05 静脈:8.40 リンパ節:5.72 末梢血:- 脾臓:7.16 胸腺:4.84 骨髄:5.27 脂肪:8.08 骨:- 皮膚:7.54
CAGE 大脳:2.81 小脳:- 脳幹:3.16 脳梁:4.12 松果体:0.79 末梢神経:- 脊柱:2.31 網膜:- 目:- 動脈:4.73 静脈:3.77 リンパ節:2.08 末梢血:- 脾臓:2.86 胸腺:0.50 骨髄:- 脂肪:3.49 骨:- 皮膚:-
RNA-seq 大脳:3.44 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:4.49 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.82 骨:- 皮膚:-
EST nodata
GeneChip 子宮:10.01 胎盤:7.12 前立腺:7.72 卵巣:8.63 精巣:7.45 心臓:8.99 骨格筋:5.60 食道:7.29 胃:8.19 腸:7.19 結腸:7.58 肝臓:5.60 肺:5.40 膀胱:- 腎臓:9.07 下垂体:4.76 甲状腺:6.64 副腎:6.55 膵臓:4.82 乳腺:10.24 唾液腺:10.24
CAGE 子宮:5.14 胎盤:3.64 前立腺:4.00 卵巣:3.92 精巣:4.01 心臓:4.18 骨格筋:1.13 食道:3.64 胃:- 腸:2.94 結腸:3.32     肝臓:1.44    肺:1.82 膀胱:3.71 腎臓:4.71 下垂体:1.03 甲状腺:2.32 副腎:- 膵臓:1.21 乳腺:4.75 唾液腺:5.32
RNA-seq 子宮:- 胎盤:- 前立腺:5.00 卵巣:5.02 精巣:5.83 心臓:3.67 骨格筋:1.43 食道:- 胃:- 腸:- 結腸:5.01     肝臓:1.04        肺:2.37    膀胱:- 腎臓:6.16 下垂体:- 甲状腺:2.95 副腎:3.20 膵臓:- 乳腺:6.67 唾液腺:-

IDs

Refseq ID NM_003012
Gene ID 6422
Unigene ID -
Probe set ID 202036_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000104332
GTEx ID ENSG00000104332

オーソログ対応遺伝子

マウス[3]  NM_013834
ラット[3]  NM_013834

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0060346  bone trabecula formation
GO:0007420  brain development
GO:0071392  cellular response to estradiol stimulus
GO:0071391  cellular response to estrogen stimulus
GO:0071363  cellular response to growth factor stimulus
GO:0071504  cellular response to heparin
GO:0071456  cellular response to hypoxia
GO:0071347  cellular response to interleukin-1
GO:0071380  cellular response to prostaglandin E stimulus
GO:0009267  cellular response to starvation
GO:0071356  cellular response to tumor necrosis factor
GO:0071305  cellular response to vitamin D
GO:0071481  cellular response to X-ray
GO:0048546  digestive tract morphogenesis
GO:0006309  DNA fragmentation involved in apoptosis
GO:0009950  dorsal/ventral axis specification
GO:0009790  embryonic development
GO:0008585  female gonad development
GO:0008406  gonad development
GO:0002244  hemopoietic progenitor cell differentiation
GO:0060218  hemopoietic stem cell differentiation
GO:0008584  male gonad development
GO:0022601  menstrual cycle phase
GO:0060766  negative regulation of androgen receptor signaling pathway
GO:0043066  negative regulation of apoptosis
GO:0045578  negative regulation of B cell differentiation
GO:0030514  negative regulation of BMP signaling pathway
GO:0046851  negative regulation of bone remodeling
GO:0030308  negative regulation of cell growth
GO:0030336  negative regulation of cell migration
GO:0008285  negative regulation of cell proliferation
GO:0050680  negative regulation of epithelial cell proliferation
GO:0010719  negative regulation of epithelial to mesenchymal transition
GO:0048147  negative regulation of fibroblast proliferation
GO:0010629  negative regulation of gene expression
GO:0046676  negative regulation of insulin secretion
GO:0043508  negative regulation of JUN kinase activity
GO:0030279  negative regulation of ossification
GO:0045668  negative regulation of osteoblast differentiation
GO:0033689  negative regulation of osteoblast proliferation
GO:0045671  negative regulation of osteoclast differentiation
GO:0050732  negative regulation of peptidyl-tyrosine phosphorylation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0014034  neural crest cell fate commitment
GO:0001843  neural tube closure
GO:0001649  osteoblast differentiation
GO:0090179  planar cell polarity pathway involved in neural tube closure
GO:0043065  positive regulation of apoptosis
GO:0030307  positive regulation of cell growth
GO:0008284  positive regulation of cell proliferation
GO:0001954  positive regulation of cell-matrix adhesion
GO:0050679  positive regulation of epithelial cell proliferation
GO:0045600  positive regulation of fat cell differentiation
GO:0051894  positive regulation of focal adhesion formation
GO:0032855  positive regulation of Rac GTPase activity
GO:0045880  positive regulation of smoothened signaling pathway
GO:0051496  positive regulation of stress fiber formation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0060527  prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0045765  regulation of angiogenesis
GO:0060687  regulation of branching involved in prostate gland morphogenesis
GO:0010564  regulation of cell cycle process
GO:0042493  response to drug
GO:0014070  response to organic cyclic substance
GO:0035019  somatic stem cell maintenance
GO:0001657  ureteric bud development
GO:0001944  vasculature development
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0042995  cell projection
GO:0009986  cell surface
GO:0005829  cytosol
GO:0031012  extracellular matrix
GO:0005615  extracellular space
GO:0005622  intracellular
GO:0005886  plasma membrane
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0004197  cysteine-type endopeptidase activity
GO:0008144  drug binding
GO:0005109  frizzled binding
GO:0008201  heparin binding
GO:0042802  identical protein binding
GO:0030165  PDZ domain binding
GO:0042813  Wnt receptor activity
GO:0017147  Wnt-protein binding