solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

詳細情報を見る

同義遺伝子名

SLC11A1, NRAMP1, Natural resistance-associated macrophage protein 1, NRAMP 1, NRAMP, LSH

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:8.30 小脳:50.40 脳幹:- 脳梁:58.30 松果体:- 末梢神経:- 脊柱:- 網膜:118.60 目:41.10 動脈:- 静脈:- リンパ節:20.20 末梢血:364.40 脾臓:132.30 胸腺:12.90 骨髄:39.40 脂肪:40.30 骨:51.20 皮膚:4.80
GeneChip 大脳:4.21 小脳:4.22 脳幹:4.35 脳梁:4.15 松果体:- 末梢神経:4.01 脊柱:4.02 網膜:- 目:- 動脈:4.03 静脈:4.40 リンパ節:4.06 末梢血:- 脾臓:4.03 胸腺:4.09 骨髄:4.56 脂肪:4.25 骨:- 皮膚:4.58
CAGE 大脳:2.61 小脳:- 脳幹:3.22 脳梁:2.70 松果体:2.94 末梢神経:- 脊柱:4.13 網膜:- 目:- 動脈:2.62 静脈:1.53 リンパ節:2.55 末梢血:- 脾臓:3.81 胸腺:0.71 骨髄:- 脂肪:3.72 骨:- 皮膚:-
RNA-seq 大脳:1.51 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.46 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.67 骨:- 皮膚:-
EST 子宮:36.50 胎盤:40.10 前立腺:- 卵巣:- 精巣:4.30 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:33.90     肝臓:-        肺:127.10    膀胱:125.60 腎臓:- 下垂体:- 甲状腺:- 副腎:50.80 膵臓:- 乳腺:9.30 唾液腺:-
GeneChip 子宮:4.02 胎盤:4.06 前立腺:3.97 卵巣:4.08 精巣:4.04 心臓:4.45 骨格筋:4.53 食道:4.07 胃:4.08 腸:4.19 結腸:4.39 肝臓:4.10 肺:5.85 膀胱:- 腎臓:4.18 下垂体:3.99 甲状腺:3.77 副腎:4.13 膵臓:4.34 乳腺:3.85 唾液腺:4.21
CAGE 子宮:1.10 胎盤:2.20 前立腺:1.42 卵巣:2.18 精巣:1.38 心臓:2.22 骨格筋:1.97 食道:1.62 胃:- 腸:0.99 結腸:0.82     肝臓:1.79    肺:4.72 膀胱:3.07 腎臓:2.07 下垂体:1.96 甲状腺:1.48 副腎:- 膵臓:1.98 乳腺:1.92 唾液腺:0.83
RNA-seq 子宮:- 胎盤:- 前立腺:0.83 卵巣:0.41 精巣:0.49 心臓:0.59 骨格筋:0.19 食道:- 胃:- 腸:- 結腸:0.64     肝臓:0.96        肺:3.56    膀胱:- 腎臓:0.92 下垂体:- 甲状腺:0.75 副腎:0.67 膵臓:- 乳腺:0.45 唾液腺:-

IDs

Refseq ID NM_000578
Gene ID 6556
Unigene ID Hs.591607
Probe set ID 217507_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000018280
GTEx ID ENSG00000018280

オーソログ対応遺伝子

マウス[1]  NM_013612
ラット[1]  NM_001031658

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0032147  activation of protein kinase activity
GO:0048002  antigen processing and presentation of peptide antigen
GO:0070574  cadmium ion transmembrane transport
GO:0006876  cellular cadmium ion homeostasis
GO:0006879  cellular iron ion homeostasis
GO:0042742  defense response to bacterium
GO:0050829  defense response to Gram-negative bacterium
GO:0042832  defense response to protozoan
GO:0070839  divalent metal ion export
GO:0006954  inflammatory response
GO:0051701  interaction with host
GO:0032623  interleukin-2 production
GO:0032632  interleukin-3 production
GO:0055072  iron ion homeostasis
GO:0006826  iron ion transport
GO:0043091  L-arginine import
GO:0042116  macrophage activation
GO:0006828  manganese ion transport
GO:0045342  MHC class II biosynthetic process
GO:0048255  mRNA stabilization
GO:0060586  multicellular organismal iron ion homeostasis
GO:0001818  negative regulation of cytokine production
GO:0015707  nitrite transport
GO:0006909  phagocytosis
GO:0001819  positive regulation of cytokine production
GO:0002606  positive regulation of dendritic cell antigen processing and presentation
GO:0010628  positive regulation of gene expression
GO:0032729  positive regulation of interferon-gamma production
GO:0050766  positive regulation of phagocytosis
GO:0002827  positive regulation of T-helper 1 type immune response
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0000060  protein import into nucleus, translocation
GO:0045730  respiratory burst
GO:0009617  response to bacterium
GO:0034341  response to interferon-gamma
GO:0032496  response to lipopolysaccharide
GO:0002369  T cell cytokine production
GO:0002309  T cell proliferation during immune response
GO:0055085  transmembrane transport
GO:0007035  vacuolar acidification
GO:0042060  wound healing

Cellular Component

GO:0009279  cell outer membrane
GO:0005887  integral to plasma membrane
GO:0005770  late endosome
GO:0031902  late endosome membrane
GO:0005764  lysosome
GO:0030670  phagocytic vesicle membrane
GO:0005886  plasma membrane
GO:0070821  tertiary granule membrane

Molecular Function

GO:0005384  manganese ion transmembrane transporter activity
GO:0051139  metal ion:hydrogen antiporter activity
GO:0042803  protein homodimerization activity
GO:0046915  transition metal ion transmembrane transporter activity