transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

詳細情報を見る

同義遺伝子名

TFAP2, AP-2, Transcription factor AP-2 alpha, Activator protein 2, AP2TF, Activating enhancer-binding protein 2 alpha, AP2-alpha, TFAP2A, AP-2 transcription factor, AP-2alpha

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:4.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:30.70 脊柱:- 網膜:237.30 目:176.30 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:67.20
GeneChip 大脳:4.20 小脳:5.26 脳幹:4.21 脳梁:4.22 松果体:- 末梢神経:5.93 脊柱:4.41 網膜:- 目:- 動脈:4.19 静脈:4.50 リンパ節:5.04 末梢血:- 脾臓:4.14 胸腺:4.25 骨髄:4.47 脂肪:4.65 骨:- 皮膚:7.92
CAGE 大脳:0.57 小脳:- 脳幹:0.53 脳梁:0.24 松果体:2.11 末梢神経:- 脊柱:0.86 網膜:- 目:- 動脈:2.34 静脈:0.88 リンパ節:2.17 末梢血:- 脾臓:0.17 胸腺:0.61 骨髄:- 脂肪:0.46 骨:- 皮膚:-
RNA-seq 大脳:0.00 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.00 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.06 骨:- 皮膚:-
EST 子宮:- 胎盤:258.70 前立腺:56.30 卵巣:- 精巣:13 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:8.50     肝臓:-        肺:19.60    膀胱:- 腎臓:41.60 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:241.60 唾液腺:-
GeneChip 子宮:4.52 胎盤:10.56 前立腺:6.64 卵巣:3.95 精巣:4.51 心臓:4.37 骨格筋:4.35 食道:7.54 胃:4.40 腸:4.33 結腸:4.74 肝臓:4.06 肺:4.10 膀胱:- 腎臓:6.37 下垂体:4.10 甲状腺:4.09 副腎:4.08 膵臓:4.61 乳腺:9.01 唾液腺:8.04
CAGE 子宮:2.13 胎盤:6.16 前立腺:3.24 卵巣:0.72 精巣:1.78 心臓:0.83 骨格筋:0.09 食道:4.28 胃:- 腸:0.69 結腸:0.51     肝臓:0.14    肺:1.35 膀胱:2.41 腎臓:3.24 下垂体:0.38 甲状腺:0.45 副腎:- 膵臓:0 乳腺:3.99 唾液腺:4.51
RNA-seq 子宮:- 胎盤:- 前立腺:0.32 卵巣:0.06 精巣:0.23 心臓:0.00 骨格筋:0 食道:- 胃:- 腸:- 結腸:0.18     肝臓:0.00        肺:0.00    膀胱:- 腎臓:0.29 下垂体:- 甲状腺:0.00 副腎:0.07 膵臓:- 乳腺:0.36 唾液腺:-

IDs

Refseq ID NM_003220
Gene ID 7020
Unigene ID Hs.519880
Probe set ID 204653_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000137203
GTEx ID ENSG00000137203

オーソログ対応遺伝子

マウス[6]  NM_001122948, NM_011547
ラット[1]  NM_001107345, NM_011547

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0021506  anterior neuropore closure
GO:0060349  bone morphogenesis
GO:0071281  cellular response to iron ion
GO:0010172  embryonic body morphogenesis
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0035115  embryonic forelimb morphogenesis
GO:0009880  embryonic pattern specification
GO:0048730  epidermis morphogenesis
GO:0060325  face morphogenesis
GO:0021884  forebrain neuron development
GO:0042472  inner ear morphogenesis
GO:0003334  keratinocyte development
GO:0001822  kidney development
GO:0060235  lens induction in camera-type eye
GO:0043066  negative regulation of apoptosis
GO:0008285  negative regulation of cell proliferation
GO:0042059  negative regulation of epidermal growth factor receptor signaling pathway
GO:0010944  negative regulation of transcription by competitive promoter binding
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0014032  neural crest cell development
GO:0021623  oculomotor nerve formation
GO:0003409  optic cup structural organization
GO:0003404  optic vesicle morphogenesis
GO:0003151  outflow tract morphogenesis
GO:0060021  palate development
GO:0030501  positive regulation of bone mineralization
GO:0030335  positive regulation of cell migration
GO:0010628  positive regulation of gene expression
GO:0043525  positive regulation of neuron apoptosis
GO:0070172  positive regulation of tooth mineralization
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0045595  regulation of cell differentiation
GO:0045664  regulation of neuron differentiation
GO:0010842  retina layer formation
GO:0007605  sensory perception of sound
GO:0048485  sympathetic nervous system development
GO:0006366  transcription from RNA polymerase II promoter
GO:0021559  trigeminal nerve development

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005794  Golgi apparatus
GO:0043231  intracellular membrane-bounded organelle
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0003682  chromatin binding
GO:0044212  DNA regulatory region binding
GO:0005515  protein binding
GO:0046983  protein dimerization activity
GO:0042803  protein homodimerization activity
GO:0043565  sequence-specific DNA binding
GO:0003713  transcription coactivator activity