transforming growth factor, beta 3

同義遺伝子名

Transforming growth factor beta-3 precursor, TGF-beta-3, TGFbeta3, TGF beta(3), transforming growth factor, beta 3, TGFbeta 3, TGF beta3, TGFB3, TGFb3, FLJ16571, ARVD, TGF beta 3, TGF-beta3

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:20.10

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:61.30

脊柱:-

網膜:-

目:47

動脈:30

静脈:-

リンパ節:-

末梢血:-

脾臓:37.80

胸腺:12.90

骨髄:19.70

脂肪:40.30

骨:12.80

皮膚:9.60

GeneChip

大脳:6.83

小脳:6.33

脳幹:6.78

脳梁:7.21

松果体:-

末梢神経:6.19

脊柱:6.89

網膜:-

目:-

動脈:7.15

静脈:8.33

リンパ節:6.55

末梢血:-

脾臓:6

胸腺:5.73

骨髄:6.13

脂肪:6.87

骨:-

皮膚:6.13

CAGE

大脳:2.26

小脳:-

脳幹:3.04

脳梁:3.25

松果体:1.52

末梢神経:-

脊柱:2.69

網膜:-

目:-

動脈:3.16

静脈:2.35

リンパ節:2.32

末梢血:-

脾臓:0.80

胸腺:1.36

骨髄:-

脂肪:1.93

骨:-

皮膚:-

RNA-seq

大脳:2.88

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:3.85

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:2.34

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:63.80

胎盤:54.60

前立腺:169

卵巣:74.50

精巣:8.70

心臓:76.60

骨格筋:-

食道:-

胃:21.20

腸:-

結腸:25.40

肝臓:21.10

肺:24.40

膀胱:-

腎臓:41.60

下垂体:-

甲状腺:-

副腎:50.80

膵臓:53.30

乳腺:27.90

唾液腺:-

GeneChip

子宮:7.01

胎盤:6.97

前立腺:7.44

卵巣:6.24

精巣:5.87

心臓:7.03

骨格筋:6.90

食道:6.15

胃:6.64

腸:6.60

結腸:6.81

肝臓:6.25

肺:6.62

膀胱:-

腎臓:6.20

下垂体:6.49

甲状腺:6.33

副腎:6.96

膵臓:6.85

乳腺:6.82

唾液腺:6.25

CAGE

子宮:3.00

胎盤:3.19

前立腺:4.16

卵巣:2.39

精巣:1.95

心臓:3.00

骨格筋:2.59

食道:1.89

胃:-

腸:1.29

結腸:1.29

肝臓:3.09

肺:2.13

膀胱:3.35

腎臓:1.99

下垂体:1.82

甲状腺:1.78

副腎:-

膵臓:1.98

乳腺:0

唾液腺:0.62

RNA-seq

子宮:-

胎盤:-

前立腺:3.54

卵巣:2.73

精巣:4.12

心臓:2.47

骨格筋:4.26

食道:-

胃:-

腸:-

結腸:3.13

肝臓:1.55

肺:5.01

膀胱:-

腎臓:2.32

下垂体:-

甲状腺:2.95

副腎:4.22

膵臓:-

乳腺:2.62

唾液腺:-

IDs

Refseq ID	NM_003239
Gene ID	7043
Unigene ID	Hs.592317
Probe set ID	209747_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000119699
GTEx ID	ENSG00000119699

オーソログ対応遺伝子

マウス[1]	NM_009368
ラット [0]

染色体

14q24.3 [76,424,442 - 76,449,334]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR001111	Transforming growth factor beta (TGFb), N-terminal
IPR015618	Transforming growth factor beta 3
IPR003911	Transforming growth factor beta TGFb
IPR003940	Transforming growth factor, beta 2
IPR016319	Transforming growth factor-beta
IPR015615	Transforming growth factor-beta-related

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0007568	aging
GO:0007596	blood coagulation
GO:0016049	cell growth
GO:0045216	cell-cell junction organization
GO:0070483	detection of hypoxia
GO:0048702	embryonic neurocranium morphogenesis
GO:0030198	extracellular matrix organization
GO:0060325	face morphogenesis
GO:0007565	female pregnancy
GO:0060364	frontal suture morphogenesis
GO:0048565	gut development
GO:0001701	in utero embryonic development
GO:0006917	induction of apoptosis
GO:0048839	inner ear development
GO:0048286	lung alveolus development
GO:0030879	mammary gland development
GO:0022601	menstrual cycle phase
GO:0008285	negative regulation of cell proliferation
GO:0008156	negative regulation of DNA replication
GO:0010936	negative regulation of macrophage cytokine production
GO:0043524	negative regulation of neuron apoptosis
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0042476	odontogenesis
GO:0043932	ossification involved in bone remodeling
GO:0060021	palate development
GO:0030168	platelet activation
GO:0002576	platelet degranulation
GO:0043065	positive regulation of apoptosis
GO:0030501	positive regulation of bone mineralization
GO:0051781	positive regulation of cell division
GO:0032967	positive regulation of collagen biosynthetic process
GO:0045740	positive regulation of DNA replication
GO:0010718	positive regulation of epithelial to mesenchymal transition
GO:0051491	positive regulation of filopodium assembly
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0050714	positive regulation of protein secretion
GO:0060391	positive regulation of SMAD protein nuclear translocation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0043627	response to estrogen stimulus
GO:0001666	response to hypoxia
GO:0034616	response to laminar fluid shear stress
GO:0032570	response to progesterone stimulus
GO:0007435	salivary gland morphogenesis
GO:0007184	SMAD protein nuclear translocation
GO:0007179	transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0043025	cell soma
GO:0009986	cell surface
GO:0031012	extracellular matrix
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0031093	platelet alpha granule lumen
GO:0030315	T-tubule

Molecular Function

GO:0008083	growth factor activity
GO:0042802	identical protein binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0050431	transforming growth factor beta binding
GO:0034713	type I transforming growth factor beta receptor binding
GO:0005114	type II transforming growth factor beta receptor binding

transforming growth factor, beta 3

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function