transforming growth factor, beta receptor 1

同義遺伝子名

ALK-5, TGFbeta receptor type I, TGFR-1, ALK5, type I TGFb receptor, type I TGF beta receptor, TGFb receptor type I, Activin receptor-like kinase 5, TGFBR1, AAT5, TGFbRI, Serine/threonine-protein kinase receptor R4, TGFbetaRI, TGFbeta R1, TGF-b receptor type I, TGF-beta receptor type I, TGF-beta receptor type-1 precursor, type I transforming growth factor beta receptor, ACVRLK4, type I TGF-beta receptor, TGF-b type I receptor, TGF beta RI, TGFb type I receptor, TGFbR1, type I TGFbeta receptor, TGF-betaRI, TGF-beta type I receptor, SKR4, TGFbeta type I receptor, TGF beta R1, TGF-beta R1, TGFBRI, type I TGF-b receptor

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:30.80

小脳:37.80

脳幹:-

脳梁:29.20

松果体:-

末梢神経:61.30

脊柱:112.30

網膜:-

目:11.80

動脈:30

静脈:-

リンパ節:70.80

末梢血:18.20

脾臓:56.70

胸腺:25.80

骨髄:98.40

脂肪:-

骨:102.40

皮膚:72

GeneChip

大脳:3.55

小脳:3.68

脳幹:3.54

脳梁:3.57

松果体:-

末梢神経:3.68

脊柱:3.70

網膜:-

目:-

動脈:3.76

静脈:3.67

リンパ節:3.59

末梢血:-

脾臓:3.62

胸腺:3.93

骨髄:3.87

脂肪:3.66

骨:-

皮膚:3.63

CAGE

大脳:2.87

小脳:-

脳幹:3.40

脳梁:3.01

松果体:2.85

末梢神経:-

脊柱:3.45

網膜:-

目:-

動脈:4.64

静脈:3.35

リンパ節:3.37

末梢血:-

脾臓:3.27

胸腺:2.73

骨髄:-

脂肪:2.97

骨:-

皮膚:-

RNA-seq

大脳:1.28

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.25

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:1.68

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:100.20

胎盤:98.40

前立腺:45.10

卵巣:74.50

精巣:73.50

心臓:51.10

骨格筋:-

食道:-

胃:-

腸:32.40

結腸:59.40

肝臓:10.60

肺:34.20

膀胱:-

腎臓:104

下垂体:232

甲状腺:-

副腎:50.80

膵臓:35.60

乳腺:65.10

唾液腺:-

GeneChip

子宮:3.61

胎盤:4.19

前立腺:3.58

卵巣:3.54

精巣:3.56

心臓:3.56

骨格筋:3.64

食道:3.58

胃:3.57

腸:3.64

結腸:3.50

肝臓:3.62

肺:3.62

膀胱:-

腎臓:3.63

下垂体:3.77

甲状腺:3.64

副腎:3.49

膵臓:3.64

乳腺:3.55

唾液腺:3.50

CAGE

子宮:3.41

胎盤:4.47

前立腺:3.21

卵巣:3.15

精巣:2.85

心臓:3.31

骨格筋:2.67

食道:3.20

胃:-

腸:2.95

結腸:3.47

肝臓:2.57

肺:3.78

膀胱:3.26

腎臓:3.19

下垂体:3.27

甲状腺:2.49

副腎:-

膵臓:2.81

乳腺:3.62

唾液腺:2.43

RNA-seq

子宮:-

胎盤:-

前立腺:3.05

卵巣:2.40

精巣:2.74

心臓:0.17

骨格筋:1.18

食道:-

胃:-

腸:-

結腸:2.34

肝臓:1.04

肺:2.62

膀胱:-

腎臓:2.76

下垂体:-

甲状腺:1.63

副腎:2.38

膵臓:-

乳腺:2.25

唾液腺:-

IDs

Refseq ID	NM_001130916
Gene ID	7046
Unigene ID	Hs.494622
Probe set ID	206943_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000106799
GTEx ID	ENSG00000106799

オーソログ対応遺伝子

マウス[3]	NM_009370
ラット [0]

染色体

9q22.33 [101,866,320 - 101,916,474]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0000186	activation of MAPKK activity
GO:0001525	angiogenesis
GO:0009952	anterior/posterior pattern formation
GO:0006915	apoptosis
GO:0048844	artery morphogenesis
GO:0001824	blastocyst development
GO:0007050	cell cycle arrest
GO:0048870	cell motility
GO:0030199	collagen fibril organization
GO:0048701	embryonic cranial skeleton morphogenesis
GO:0043542	endothelial cell migration
GO:0001837	epithelial to mesenchymal transition
GO:0043062	extracellular structure organization
GO:0008354	germ cell migration
GO:0007507	heart development
GO:0001701	in utero embryonic development
GO:0006917	induction of apoptosis
GO:0001822	kidney development
GO:0002088	lens development in camera-type eye
GO:0048762	mesenchymal cell differentiation
GO:0043066	negative regulation of apoptosis
GO:0032331	negative regulation of chondrocyte differentiation
GO:0001937	negative regulation of endothelial cell proliferation
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0048663	neuron fate commitment
GO:0060021	palate development
GO:0060017	parathyroid gland development
GO:0060389	pathway-restricted SMAD protein phosphorylation
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation
GO:0060037	pharyngeal system development
GO:0030307	positive regulation of cell growth
GO:0008284	positive regulation of cell proliferation
GO:0051272	positive regulation of cellular component movement
GO:0051491	positive regulation of filopodium assembly
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0060391	positive regulation of SMAD protein nuclear translocation
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0009791	post-embryonic development
GO:0006468	protein amino acid phosphorylation
GO:0043393	regulation of protein binding
GO:0031396	regulation of protein ubiquitination
GO:0006355	regulation of transcription, DNA-dependent
GO:0070723	response to cholesterol
GO:0007165	signal transduction
GO:0001501	skeletal system development
GO:0048705	skeletal system morphogenesis
GO:0048538	thymus development
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0042060	wound healing

Cellular Component

GO:0005886	plasma membrane
GO:0043235	receptor complex
GO:0005923	tight junction
GO:0070022	transforming growth factor beta receptor complex

Molecular Function

GO:0005524	ATP binding
GO:0019838	growth factor binding
GO:0070411	I-SMAD binding
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0046332	SMAD binding
GO:0050431	transforming growth factor beta binding
GO:0005024	transforming growth factor beta receptor activity
GO:0005025	transforming growth factor beta receptor activity, type I
GO:0004675	transmembrane receptor protein serine/threonine kinase activity
GO:0005114	type II transforming growth factor beta receptor binding

transforming growth factor, beta receptor 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function