tyrosine hydroxylase

詳細情報を見る

同義遺伝子名

TYH, Tyrosine 3-hydroxylase, TH, tyrosine hydroxylase, Tyrosine 3-monooxygenase

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:1.20 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:561.50 網膜:- 目:11.80 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:3.77 小脳:3.56 脳幹:6.56 脳梁:3.43 松果体:- 末梢神経:3.55 脊柱:3.22 網膜:- 目:- 動脈:3.77 静脈:3.68 リンパ節:4.33 末梢血:- 脾臓:3.34 胸腺:3.36 骨髄:3.66 脂肪:3.63 骨:- 皮膚:4.05
CAGE 大脳:0.43 小脳:- 脳幹:1.50 脳梁:2.06 松果体:0.21 末梢神経:- 脊柱:0.09 網膜:- 目:- 動脈:0.47 静脈:2.03 リンパ節:0 末梢血:- 脾臓:0.17 胸腺:0 骨髄:- 脂肪:0 骨:- 皮膚:-
RNA-seq 大脳:0.10 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.78 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0 骨:- 皮膚:-
EST 子宮:- 胎盤:7.30 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:50.80 膵臓:17.80 乳腺:- 唾液腺:-
GeneChip 子宮:3.55 胎盤:3.29 前立腺:3.49 卵巣:3.71 精巣:3.62 心臓:3.46 骨格筋:3.64 食道:3.58 胃:3.45 腸:3.69 結腸:3.39 肝臓:3.48 肺:3.45 膀胱:- 腎臓:3.42 下垂体:3.56 甲状腺:3.44 副腎:6.54 膵臓:4.16 乳腺:3.56 唾液腺:3.41
CAGE 子宮:0.60 胎盤:0.88 前立腺:0.74 卵巣:0.26 精巣:0 心臓:0 骨格筋:0 食道:0.40 胃:- 腸:0.38 結腸:0.43     肝臓:0    肺:0.17 膀胱:1.15 腎臓:0.08 下垂体:0.50 甲状腺:0 副腎:- 膵臓:0 乳腺:0 唾液腺:0
RNA-seq 子宮:- 胎盤:- 前立腺:0.73 卵巣:0.12 精巣:0.38 心臓:0.01 骨格筋:0 食道:- 胃:- 腸:- 結腸:0.05     肝臓:0        肺:0.04    膀胱:- 腎臓:0.10 下垂体:- 甲状腺:0.06 副腎:0.04 膵臓:- 乳腺:0.01 唾液腺:-

IDs

Refseq ID NM_000360
Gene ID 7054
Unigene ID Hs.435609
Probe set ID 208291_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000180176
GTEx ID ENSG00000180176

オーソログ対応遺伝子

マウス[1]  NM_009377
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

33381
1347949
1973163
2872999
2874140
2882428
2887169
2888085
2892528
2892893
2896667
2902075
2905129
6137760
6150037
7715703
7789962
7814018
7901013
8101641
8528210
8817341
8889548
9613851
9703425
9754624
9920892
10391209
10660577
10907721
11246459
11326301
11359875
11738155
11834745
11943812
12113410
12358785
12421349
12428766
12457228
12477932
12493595
12527603
12571119
12576454
12610512
12631248
12759555
12782971
12891655
12952878
14570886
14651963
14651989
14675149
14739699
14749349
15077008
15135070
15303408
15468323
15476168
15722952
15735319
15736042
15744773
15898085
15953356
16139102
16251897
16252282
16338639
16344718
16360899
16445854
16447258
16516890
16636198
16643317
16644734
16731528
16741719
16764822
16887311
17018139
17135716
17194738
17195153
17329957
17391063
17466074
17520326
17698383
17698732
17784840
17869399
17926059
17948905
17972051
17985144
17988588
18023073
18058633
18085551
18181650
18208403
18270970
18343820
18534229
18554280
18574609
18583979
18814238
18979915
19120120
19125082
19156168
19189602
19221445
19224593
19285077
19352218
19360691
19367319
19448984
19491146
19491717
19604093
19674121
19693267
19703902
19761814
19767753
19772578
19801645
19815691
19833152
19874574
19913121
19958792
20046397
20056467
20067853
20124442
20132525
20146650
20163778
20198643
20301334
20301610
20468064
20564319
20571875
20602615
20628086
20646572
20675101
20706199
20734064
20809526
20818075
20838244
20938049
21083670
21087208
21158937
21265843
21368136
21392500
21407269
21656370
21815951
22001923
22002062
22066143
22083667
22272358
22336227
22583432
22691284
22815559
23182718
23444366
23481708
23489065
23647419
23762320
23936387
23977047
24055376
24168553

遺伝子オントロジー  (GO ID)

Biological Process

GO:0009653  anatomical structure morphogenesis
GO:0042423  catecholamine biosynthetic process
GO:0034641  cellular nitrogen compound metabolic process
GO:0071333  cellular response to glucose stimulus
GO:0071363  cellular response to growth factor stimulus
GO:0071287  cellular response to manganese ion
GO:0071316  cellular response to nicotine
GO:0021987  cerebral cortex development
GO:0042745  circadian sleep/wake cycle
GO:0042416  dopamine biosynthetic process
GO:0006585  dopamine biosynthetic process from tyrosine
GO:0042755  eating behavior
GO:0048596  embryonic camera-type eye morphogenesis
GO:0042418  epinephrine biosynthetic process
GO:0042462  eye photoreceptor cell development
GO:0006631  fatty acid metabolic process
GO:0016137  glycoside metabolic process
GO:0007507  heart development
GO:0003007  heart morphogenesis
GO:0033076  isoquinoline alkaloid metabolic process
GO:0007612  learning
GO:0007626  locomotory behavior
GO:0007617  mating behavior
GO:0007613  memory
GO:0010259  multicellular organismal aging
GO:0042136  neurotransmitter biosynthetic process
GO:0042421  norepinephrine biosynthetic process
GO:0009887  organ morphogenesis
GO:0018963  phthalate metabolic process
GO:0052314  phytoalexin metabolic process
GO:0043473  pigmentation
GO:0008016  regulation of heart contraction
GO:0014823  response to activity
GO:0001975  response to amphetamine
GO:0051412  response to corticosterone stimulus
GO:0051602  response to electrical stimulus
GO:0032355  response to estradiol stimulus
GO:0045471  response to ethanol
GO:0045472  response to ether
GO:0009635  response to herbicide
GO:0001666  response to hypoxia
GO:0009416  response to light stimulus
GO:0032496  response to lipopolysaccharide
GO:0031667  response to nutrient levels
GO:0043434  response to peptide hormone stimulus
GO:0046684  response to pyrethroid
GO:0009651  response to salt stress
GO:0009414  response to water deprivation
GO:0010043  response to zinc ion
GO:0007605  sensory perception of sound
GO:0035176  social behavior
GO:0006665  sphingolipid metabolic process
GO:0001963  synaptic transmission, dopaminergic
GO:0015842  synaptic vesicle amine transport
GO:0042214  terpene metabolic process
GO:0007601  visual perception

Cellular Component

GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0005829  cytosol
GO:0030425  dendrite
GO:0009898  internal side of plasma membrane
GO:0033162  melanosome membrane
GO:0005739  mitochondrion
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0043204  perikaryon
GO:0005790  smooth endoplasmic reticulum
GO:0008021  synaptic vesicle
GO:0043195  terminal button

Molecular Function

GO:0016597  amino acid binding
GO:0035240  dopamine binding
GO:0008199  ferric iron binding
GO:0008198  ferrous iron binding
GO:0019825  oxygen binding
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0034617  tetrahydrobiopterin binding
GO:0004511  tyrosine 3-monooxygenase activity