thrombospondin 1

詳細情報を見る

同義遺伝子名

THBS1, Thrombospondin-1 precursor, TSP, thrombospondin 1, TSP1, THBS

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:26.10

小脳:-

脳幹:-

脳梁:583.20

松果体:-

末梢神経:184

脊柱:224.60

網膜:237.30

目:70.50

動脈:1498.80

静脈:799.80

リンパ節:50.60

末梢血:109.30

脾臓:18.90

胸腺:51.50

骨髄:255.80

脂肪:161.30

骨:870.10

皮膚:259.20

GeneChip

大脳:3.42

小脳:3.52

脳幹:3.73

脳梁:3.43

松果体:-

末梢神経:6.01

脊柱:4.51

網膜:-

目:-

動脈:5.90

静脈:8.12

リンパ節:4.68

末梢血:-

脾臓:5.55

胸腺:3.91

骨髄:4.94

脂肪:6.02

骨:-

皮膚:5.52

CAGE

大脳:2.54

小脳:-

脳幹:2.97

脳梁:3.08

松果体:3.37

末梢神経:-

脊柱:3.10

網膜:-

目:-

動脈:5.65

静脈:4.85

リンパ節:5.27

末梢血:-

脾臓:6.04

胸腺:1.96

骨髄:-

脂肪:5.69

骨:-

皮膚:-

RNA-seq

大脳:3.14

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:5.96

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:7.94

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:264.30

胎盤:134.80

前立腺:202.80

卵巣:149.10

精巣:8.70

心臓:76.60

骨格筋:-

食道:-

胃:297.40

腸:32.40

結腸:356.10

肝臓:95

肺:195.50

膀胱:251.20

腎臓:249.50

下垂体:-

甲状腺:163.70

副腎:50.80

膵臓:88.90

乳腺:659.80

唾液腺:-

GeneChip

子宮:6.95

胎盤:6.67

前立腺:6.49

卵巣:6.91

精巣:3.50

心臓:6.04

骨格筋:3.90

食道:4.68

胃:5.87

腸:6.44

結腸:5.67

肝臓:3.96

肺:7.85

膀胱:-

腎臓:5.65

下垂体:4.28

甲状腺:3.98

副腎:5.01

膵臓:4.87

乳腺:5.53

唾液腺:5.22

CAGE

子宮:5.83

胎盤:5.56

前立腺:5.51

卵巣:6.09

精巣:4.36

心臓:6.06

骨格筋:4.37

食道:5.13

胃:-

腸:5.11

結腸:5.10

肝臓:4.43

肺:6.23

膀胱:6.71

腎臓:5.14

下垂体:4.32

甲状腺:4.58

副腎:-

膵臓:4.28

乳腺:5.73

唾液腺:5.07

RNA-seq

子宮:-

胎盤:-

前立腺:5.92

卵巣:6.22

精巣:4.64

心臓:5.09

骨格筋:2.84

食道:-

胃:-

腸:-

結腸:7.50

肝臓:3.01

肺:9.05

膀胱:-

腎臓:5.52

下垂体:-

甲状腺:4.01

副腎:5.67

膵臓:-

乳腺:6.44

唾液腺:-

IDs

Refseq ID	NM_003246
Gene ID	7057
Unigene ID	Hs.164226
Probe set ID	201109_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000137801
GTEx ID	ENSG00000137801

オーソログ対応遺伝子

マウス[3]	NM_011580
ラット[3]	NM_011580

染色体

15q14 [39,873,127 - 39,891,119]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR001881	EGF-like calcium-binding
IPR000742	EGF-like, type 3
IPR000884	Thrombospondin, type 1 repeat

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0007596	blood coagulation
GO:0007155	cell adhesion
GO:0007050	cell cycle arrest
GO:0016477	cell migration
GO:0034605	cellular response to heat
GO:0002544	chronic inflammatory response
GO:0003197	endocardial cushion development
GO:0043652	engulfment of apoptotic cell
GO:0030198	extracellular matrix organization
GO:0003417	growth plate cartilage development
GO:0006955	immune response
GO:0016525	negative regulation of angiogenesis
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0043066	negative regulation of apoptosis
GO:0043537	negative regulation of blood vessel endothelial cell migration
GO:0043154	negative regulation of caspase activity
GO:0001953	negative regulation of cell-matrix adhesion
GO:0010754	negative regulation of cGMP-mediated signaling
GO:0002605	negative regulation of dendritic cell antigen processing and presentation
GO:0010596	negative regulation of endothelial cell migration
GO:0001937	negative regulation of endothelial cell proliferation
GO:0051918	negative regulation of fibrinolysis
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
GO:0051895	negative regulation of focal adhesion formation
GO:0032695	negative regulation of interleukin-12 production
GO:0010751	negative regulation of nitric oxide mediated signal transduction
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport
GO:0010757	negative regulation of plasminogen activation
GO:0003151	outflow tract morphogenesis
GO:0018149	peptide cross-linking
GO:0030168	platelet activation
GO:0002576	platelet degranulation
GO:0045766	positive regulation of angiogenesis
GO:0030194	positive regulation of blood coagulation
GO:0043536	positive regulation of blood vessel endothelial cell migration
GO:0030335	positive regulation of cell migration
GO:0010811	positive regulation of cell-substrate adhesion
GO:0050921	positive regulation of chemotaxis
GO:0010595	positive regulation of endothelial cell migration
GO:0010763	positive regulation of fibroblast migration
GO:0043032	positive regulation of macrophage activation
GO:0010759	positive regulation of macrophage chemotaxis
GO:0042327	positive regulation of phosphorylation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway
GO:0032914	positive regulation of transforming growth factor-beta1 production
GO:0045727	positive regulation of translation
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
GO:0051592	response to calcium ion
GO:0042493	response to drug
GO:0009749	response to glucose stimulus
GO:0001666	response to hypoxia
GO:0032026	response to magnesium ion
GO:0032570	response to progesterone stimulus
GO:0002040	sprouting angiogenesis

Cellular Component

GO:0009986	cell surface
GO:0009897	external side of plasma membrane
GO:0031012	extracellular matrix
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0070062	extracellular vesicular exosome
GO:0005577	fibrinogen complex
GO:0031091	platelet alpha granule
GO:0031093	platelet alpha granule lumen
GO:0030141	secretory granule

Molecular Function

GO:0005509	calcium ion binding
GO:0070052	collagen V binding
GO:0070051	fibrinogen binding
GO:0017134	fibroblast growth factor binding
GO:0001968	fibronectin binding
GO:0001948	glycoprotein binding
GO:0008201	heparin binding
GO:0042802	identical protein binding
GO:0005178	integrin binding
GO:0043236	laminin binding
GO:0030169	low-density lipoprotein binding
GO:0001786	phosphatidylserine binding
GO:0005515	protein binding
GO:0043394	proteoglycan binding
GO:0050431	transforming growth factor beta binding

thrombospondin 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function