thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)

詳細情報を見る

同義遺伝子名

c-erbA-1, NR1A1, THRA1, ERBA-ALPHA, THRA2, EAR-7.2, c-ERBA-ALPHA-2, Thyroid hormone receptor alpha, EAR-7, EAR-7.1/EAR-7.2, EAR-7.1, TR-ALPHA-1, ERBA, ERB-T-1, ERBA1, c-ERBA-1, AR7, MGC43240, MGC000261, EAR7, THRA, THRA3, C-erbA-alpha

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:20.10 小脳:- 脳幹:- 脳梁:29.20 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:41.10 動脈:- 静脈:- リンパ節:10.10 末梢血:18.20 脾臓:- 胸腺:12.90 骨髄:- 脂肪:- 骨:12.80 皮膚:9.60
GeneChip 大脳:5.20 小脳:5.34 脳幹:5.24 脳梁:5.21 松果体:- 末梢神経:5.14 脊柱:5.08 網膜:- 目:- 動脈:5.39 静脈:5.61 リンパ節:5.17 末梢血:- 脾臓:5.01 胸腺:5.08 骨髄:5.70 脂肪:5.55 骨:- 皮膚:5.48
CAGE 大脳:5.19 小脳:- 脳幹:4.66 脳梁:4.89 松果体:4.11 末梢神経:- 脊柱:5.01 網膜:- 目:- 動脈:4.05 静脈:3.36 リンパ節:2.61 末梢血:- 脾臓:2.49 胸腺:2.46 骨髄:- 脂肪:3.65 骨:- 皮膚:-
RNA-seq 大脳:2.33 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.40 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.63 骨:- 皮膚:-
EST 子宮:18.20 胎盤:47.40 前立腺:22.50 卵巣:- 精巣:30.30 心臓:12.80 骨格筋:- 食道:- 胃:- 腸:32.40 結腸:8.50     肝臓:-        肺:14.70    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:50.80 膵臓:- 乳腺:9.30 唾液腺:-
GeneChip 子宮:5.10 胎盤:5.09 前立腺:4.92 卵巣:5.26 精巣:5.02 心臓:5.40 骨格筋:5.54 食道:5.44 胃:5.09 腸:5.38 結腸:5.24 肝臓:5.34 肺:5.42 膀胱:- 腎臓:5.15 下垂体:5.26 甲状腺:5.05 副腎:5.32 膵臓:5.55 乳腺:5.12 唾液腺:5.69
CAGE 子宮:4.33 胎盤:2.73 前立腺:4.04 卵巣:3.77 精巣:3.30 心臓:3.98 骨格筋:3.99 食道:3.47 胃:- 腸:3.70 結腸:4.08     肝臓:1.90    肺:3.38 膀胱:3.88 腎臓:3.61 下垂体:3.56 甲状腺:3.69 副腎:- 膵臓:3.34 乳腺:4.34 唾液腺:3.63
RNA-seq 子宮:- 胎盤:- 前立腺:2.77 卵巣:2.71 精巣:1.93 心臓:2.52 骨格筋:2.85 食道:- 胃:- 腸:- 結腸:2.79     肝臓:0.85        肺:2.04    膀胱:- 腎臓:2.11 下垂体:- 甲状腺:2.39 副腎:1.91 膵臓:- 乳腺:2.95 唾液腺:-

IDs

Refseq ID NM_199334
Gene ID 7067
Unigene ID Hs.72451
Probe set ID 214883_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000126351
GTEx ID ENSG00000126351

オーソログ対応遺伝子

マウス[2]  NM_178060
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001502  cartilage condensation
GO:0042994  cytoplasmic sequestering of transcription factor
GO:0030218  erythrocyte differentiation
GO:0008050  female courtship behavior
GO:0010467  gene expression
GO:0009755  hormone-mediated signaling pathway
GO:0007611  learning or memory
GO:0017055  negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0001503  ossification
GO:0045925  positive regulation of female receptivity
GO:0010831  positive regulation of myotube differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0008016  regulation of heart contraction
GO:0050994  regulation of lipid catabolic process
GO:0033032  regulation of myeloid cell apoptosis
GO:0002155  regulation of thyroid hormone mediated signaling pathway
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0009409  response to cold
GO:0030878  thyroid gland development
GO:0006366  transcription from RNA polymerase II promoter
GO:0006367  transcription initiation from RNA polymerase II promoter

Cellular Component

GO:0005829  cytosol
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0031490  chromatin DNA binding
GO:0044212  DNA regulatory region binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0019904  protein domain specific binding
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0002153  steroid receptor RNA activator RNA binding
GO:0017025  TATA-binding protein binding
GO:0070324  thyroid hormone binding
GO:0004887  thyroid hormone receptor activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0008270  zinc ion binding