TNF receptor-associated factor 2

詳細情報を見る

同義遺伝子名

TRAP3, MGC:45012, TRAF2, TNF receptor-associated factor 2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:72.30 小脳:100.80 脳幹:- 脳梁:29.20 松果体:- 末梢神経:30.70 脊柱:- 網膜:- 目:47 動脈:- 静脈:199.90 リンパ節:10.10 末梢血:109.30 脾臓:453.80 胸腺:438 骨髄:59 脂肪:40.30 骨:191.90 皮膚:96
GeneChip 大脳:6.42 小脳:6.77 脳幹:6.47 脳梁:6.52 松果体:- 末梢神経:6.25 脊柱:6.35 網膜:- 目:- 動脈:6.49 静脈:6.63 リンパ節:6.95 末梢血:- 脾臓:6.71 胸腺:6.66 骨髄:6.60 脂肪:6.57 骨:- 皮膚:6.37
CAGE 大脳:1.56 小脳:- 脳幹:1.60 脳梁:1.51 松果体:1.26 末梢神経:- 脊柱:1.18 網膜:- 目:- 動脈:1.97 静脈:1.92 リンパ節:2.11 末梢血:- 脾臓:1.71 胸腺:2.02 骨髄:- 脂肪:1.47 骨:- 皮膚:-
RNA-seq 大脳:1.23 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.26 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.87 骨:- 皮膚:-
EST 子宮:27.30 胎盤:36.40 前立腺:90.10 卵巣:74.50 精巣:60.60 心臓:12.80 骨格筋:- 食道:- 胃:42.50 腸:226.80 結腸:59.40     肝臓:-        肺:68.40    膀胱:125.60 腎臓:31.20 下垂体:- 甲状腺:- 副腎:101.60 膵臓:- 乳腺:65.10 唾液腺:-
GeneChip 子宮:6.43 胎盤:6.60 前立腺:6.20 卵巣:6.41 精巣:6.50 心臓:6.50 骨格筋:6.70 食道:6.77 胃:6.63 腸:6.54 結腸:6.66 肝臓:6.63 肺:6.66 膀胱:- 腎臓:6.46 下垂体:6.72 甲状腺:6.62 副腎:6.51 膵臓:6.65 乳腺:6.64 唾液腺:6.52
CAGE 子宮:1.76 胎盤:1.87 前立腺:1.82 卵巣:1.31 精巣:1.62 心臓:1.11 骨格筋:1.20 食道:1.64 胃:- 腸:1.60 結腸:2.11     肝臓:1.21    肺:1.73 膀胱:1.32 腎臓:1.24 下垂体:1.60 甲状腺:2.01 副腎:- 膵臓:1.87 乳腺:1.53 唾液腺:2.06
RNA-seq 子宮:- 胎盤:- 前立腺:2.02 卵巣:1.81 精巣:2.89 心臓:0.72 骨格筋:1.85 食道:- 胃:- 腸:- 結腸:2.31     肝臓:1.07        肺:2.40    膀胱:- 腎臓:1.87 下垂体:- 甲状腺:2.40 副腎:2.72 膵臓:- 乳腺:1.64 唾液腺:-

IDs

Refseq ID NM_021138
Gene ID 7186
Unigene ID Hs.522506
Probe set ID 204413_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000127191
GTEx ID ENSG00000127191

オーソログ対応遺伝子

マウス[1]  NM_009422
ラット[1]  NM_001107815

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

7639698
7758105
8069916
8125298
8548810
8565075
8612133
8627180
8643514
8662842
8692885
8702708
8710854
8875942
8943045
8985011
8999898
9020361
9104814
9153189
9162022
9168896
9208847
9244310
9275204
9353251
9384571
9418902
9461607
9464265
9488716
9500555
9582383
9607925
9685412
9692890
9705938
9712898
9718306
9733516
9774460
9774977
9794406
9827693
9852070
9990007
10025951
10037686
10075662
10206649
10339433
10346818
10352240
10411888
10477597
10490605
10514511
10521462
10523862
10544141
10581243
10617615
10650002
10753917
10759890
10764746
10809768
10837247
10880535
10882101
10892748
10903733
10911999
10980203
10990461
11035039
11057907
11064452
11112773
11181075
11278268
11278723
11279055
11340079
11359906
11384837
11435475
11466612
11479302
11562359
11607847
11728344
11777919
11784851
11798190
11804591
11805080
11821416
11882293
11907088
11907583
11909853
11932422
11971184
12005438
12136106
12169272
12220533
12296995
12411322
12411493
12477932
12529173
12547194
12571250
12591926
12637493
12796506
12842894
12843613
12867425
12887920
12917689
12917690
12917691
14517219
14557256
14585990
14633987
14644197
14702039
14741690
14743216
14982987
15084608
15121867
15125833
15208311
15258597
15265700
15308666
15310755
15327770
15383523
15485634
15485837
15489334
15670770
15670977
15696169
15707590
15708970
15743837
15861135
15941918
15944293
16009713
16153868
16189514
16214042
16227629
16260598
16263936
16282325
16291755
16304992
16311516
16341674
16378096
16446357
16603398
16611992
16636664
16713569
16876162
16891304
16936264
17015619
17314283
17379600
17384642
17389591
17544371
17599408
17626074
17724081
17851586
17923499
18022363
18024283
18029348
18069092
18230756
18271526
18292192
18312353
18362156
18362886
18671942
18776134
18787502
18818748
18827186
18950704
18981220
18990758
19019335
19150425
19151112
19234489
19243308
19287455
19336370
19380743
19453261
19506082
19527514
19573080
19584093
19586614
19667091
19690440
19773279
19795416
19810754
19815509
19815541
19937093
20005846
20047764
20056178
20064526
20133937
20138174
20184394
20237496
20333651
20348096
20368287
20385093
20447407
20448643
20449947
20562859
20568250
20577214
20585848
20614026
20628086
20676093
20732415
20856938
20949042
20972266
21041452
21041727
21071692
21078302
21078624
21119000
21139048
21229359
21266470
21282461
21282507
21289304
21325409
21331077
21421854
21620750
21653699
21793045
21810480
21864338
21886773
21890473
21903422
21906983
21921033
21963094
21987572
21988832
22029577
22078441
22167321
22170762
22179575
22184250
22195745
22212761
22271254
22343716
22505724
22525270
22550173
22585859
22685297
22711886
22732732
22792062
22847298
22863753
23000965
23007157
23051914
23088713
23142077
23160117
23188828
23301098
23319823
23357418
23381138
23405219
23414308
23453969
23524849
23543740
23595117
23608757
23624947
23638224
23690480
23743189
23754945
23774506
23775076
23885119
23890813
23918987
23972990
24008839
24276241
24429366
24434549
24457600
24464131
24726327
24735611
24841215

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0007250  activation of NF-kappaB-inducing kinase activity
GO:0006915  apoptosis
GO:0043623  cellular protein complex assembly
GO:0045087  innate immune response
GO:0032743  positive regulation of interleukin-2 production
GO:0043507  positive regulation of JUN kinase activity
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0090073  positive regulation of protein homodimerization activity
GO:0050870  positive regulation of T cell activation
GO:0002726  positive regulation of T cell cytokine production
GO:0051091  positive regulation of transcription factor activity
GO:0051865  protein autoubiquitination
GO:0030163  protein catabolic process
GO:0006461  protein complex assembly
GO:0070207  protein homotrimerization
GO:0070534  protein K63-linked ubiquitination
GO:0042981  regulation of apoptosis
GO:0051023  regulation of immunoglobulin secretion
GO:0007165  signal transduction
GO:0033209  tumor necrosis factor-mediated signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0009898  internal side of plasma membrane

Molecular Function

GO:0005174  CD40 receptor binding
GO:0019899  enzyme binding
GO:0042802  identical protein binding
GO:0005515  protein binding
GO:0019903  protein phosphatase binding
GO:0004871  signal transducer activity
GO:0046625  sphingolipid binding
GO:0031996  thioesterase binding
GO:0005164  tumor necrosis factor receptor binding
GO:0031625  ubiquitin protein ligase binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding