axin 1

詳細情報を見る

同義遺伝子名

AXIN, hAxin, Axis inhibition protein 1, MGC52315, Axin-1, AXIN1, axin 1

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:16.60

小脳:75.60

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:5.90

動脈:-

静脈:-

リンパ節:151.70

末梢血:18.20

脾臓:18.90

胸腺:-

骨髄:236.20

脂肪:-

骨:-

皮膚:43.20

GeneChip

大脳:6.54

小脳:6.65

脳幹:6.46

脳梁:6.55

松果体:-

末梢神経:6.40

脊柱:6.54

網膜:-

目:-

動脈:6.78

静脈:6.66

リンパ節:6.85

末梢血:-

脾臓:7.05

胸腺:6.66

骨髄:7.29

脂肪:6.75

骨:-

皮膚:6.75

CAGE

大脳:2.23

小脳:-

脳幹:2.14

脳梁:2.37

松果体:1.90

末梢神経:-

脊柱:2.14

網膜:-

目:-

動脈:2.70

静脈:2.46

リンパ節:2.29

末梢血:-

脾臓:2.09

胸腺:2.48

骨髄:-

脂肪:1.71

骨:-

皮膚:-

RNA-seq

大脳:0.02

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:2.06

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:1.01

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:18.20

胎盤:7.30

前立腺:-

卵巣:-

精巣:34.60

心臓:-

骨格筋:-

食道:-

胃:42.50

腸:-

結腸:84.80

肝臓:42.20

肺:34.20

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:8.90

乳腺:46.50

唾液腺:-

GeneChip

子宮:6.54

胎盤:6.35

前立腺:6.40

卵巣:6.53

精巣:6.81

心臓:6.43

骨格筋:6.53

食道:6.61

胃:6.72

腸:6.78

結腸:7.08

肝臓:6.55

肺:6.68

膀胱:-

腎臓:6.66

下垂体:6.85

甲状腺:6.74

副腎:6.59

膵臓:6.72

乳腺:6.87

唾液腺:6.73

CAGE

子宮:2.16

胎盤:1.87

前立腺:2.24

卵巣:2.02

精巣:2.17

心臓:2.27

骨格筋:2.37

食道:2.08

胃:-

腸:2.38

結腸:2.82

肝臓:1.47

肺:2.46

膀胱:2.25

腎臓:2.01

下垂体:1.87

甲状腺:2.29

副腎:-

膵臓:2.18

乳腺:2.91

唾液腺:1.49

RNA-seq

子宮:-

胎盤:-

前立腺:1.68

卵巣:1.89

精巣:1.45

心臓:0.50

骨格筋:1.93

食道:-

胃:-

腸:-

結腸:1.30

肝臓:0.51

肺:1.99

膀胱:-

腎臓:1.06

下垂体:-

甲状腺:1.66

副腎:0.96

膵臓:-

乳腺:0.81

唾液腺:-

IDs

Refseq ID	NM_003502
Gene ID	8312
Unigene ID	Hs.592082
Probe set ID	212849_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000103126
GTEx ID	ENSG00000103126

オーソログ対応遺伝子

マウス[3]	NM_001159598, NM_009733
ラット [0]

染色体

16p13.3 [337,440 - 402,673]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000342	Regulator of G protein signalling
IPR016137	Regulator of G protein signalling superfamily

遺伝子オントロジー (GO ID)

Biological Process

GO:0007257	activation of JUN kinase activity
GO:0032147	activation of protein kinase activity
GO:0006915	apoptosis
GO:0048320	axial mesoderm formation
GO:0008219	cell death
GO:0043623	cellular protein complex assembly
GO:0071407	cellular response to organic cyclic substance
GO:0031122	cytoplasmic microtubule organization
GO:0007368	determination of left/right symmetry
GO:0009950	dorsal/ventral axis specification
GO:0048048	embryonic eye morphogenesis
GO:0060272	embryonic skeletal joint morphogenesis
GO:0021797	forebrain anterior/posterior pattern formation
GO:0001701	in utero embryonic development
GO:0055001	muscle cell development
GO:0045599	negative regulation of fat cell differentiation
GO:0051248	negative regulation of protein metabolic process
GO:0034244	negative regulation of RNA elongation from RNA polymerase II promoter
GO:0030178	negative regulation of Wnt receptor signaling pathway
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0006913	nucleocytoplasmic transport
GO:0030910	olfactory placode formation
GO:0001743	optic placode formation
GO:0043547	positive regulation of GTPase activity
GO:0046330	positive regulation of JNK cascade
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0010800	positive regulation of peptidyl-threonine phosphorylation
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0045732	positive regulation of protein catabolic process
GO:0031398	positive regulation of protein ubiquitination
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway
GO:0051443	positive regulation of ubiquitin-protein ligase activity
GO:0030163	protein catabolic process
GO:0051260	protein homooligomerization
GO:0000209	protein polyubiquitination
GO:0007605	sensory perception of sound
GO:0021881	Wnt receptor signaling pathway involved in forebrain neuron fate commitment
GO:0060070	Wnt receptor signaling pathway through beta-catenin
GO:0060823	Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation

Cellular Component

GO:0030877	beta-catenin destruction complex
GO:0005938	cell cortex
GO:0005737	cytoplasm
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0005881	cytoplasmic microtubule
GO:0031410	cytoplasmic vesicle
GO:0005829	cytosol
GO:0016328	lateral plasma membrane
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0014069	postsynaptic density

Molecular Function

GO:0070016	armadillo repeat domain binding
GO:0008013	beta-catenin binding
GO:0019899	enzyme binding
GO:0005096	GTPase activator activity
GO:0070411	I-SMAD binding
GO:0042802	identical protein binding
GO:0002039	p53 binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0032947	protein complex scaffold
GO:0042803	protein homodimerization activity
GO:0019901	protein kinase binding
GO:0043621	protein self-association
GO:0070412	R-SMAD binding
GO:0004871	signal transducer activity
GO:0046332	SMAD binding
GO:0031625	ubiquitin protein ligase binding

axin 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function