runt-related transcription factor 1

詳細情報を見る

同義遺伝子名

AMLCR1, PEBP2aB, PEBP2A2, PEA2-alpha B, Acute myeloid leukemia 1 protein, SL3/AKV core-binding factor alpha B subunit, PEBP2-alpha B, EVI-1, Core-binding factor, alpha 2 subunit, CBFA2, Runt-related transcription factor 1, SL3-3 enhancer factor 1 alpha B subunit, CBF-alpha 2, AML1, RUNX1, Oncogene AML-1, AML1-EVI-1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:14.20 小脳:- 脳幹:- 脳梁:29.20 松果体:- 末梢神経:30.70 脊柱:- 網膜:- 目:17.60 動脈:30 静脈:66.60 リンパ節:40.40 末梢血:127.50 脾臓:94.50 胸腺:322.10 骨髄:688.80 脂肪:80.70 骨:76.80 皮膚:105.60
GeneChip 大脳:5.50 小脳:5.27 脳幹:5.52 脳梁:5.58 松果体:- 末梢神経:6.81 脊柱:5.50 網膜:- 目:- 動脈:6.39 静脈:6.36 リンパ節:6.57 末梢血:- 脾臓:6.57 胸腺:8.20 骨髄:7.17 脂肪:6.24 骨:- 皮膚:6.71
CAGE 大脳:2.60 小脳:- 脳幹:3.02 脳梁:2.88 松果体:2.82 末梢神経:- 脊柱:3.99 網膜:- 目:- 動脈:4.24 静脈:3.98 リンパ節:4.00 末梢血:- 脾臓:3.69 胸腺:5.17 骨髄:- 脂肪:3.76 骨:- 皮膚:-
RNA-seq 大脳:0.31 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.43 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.87 骨:- 皮膚:-
EST 子宮:209.60 胎盤:36.40 前立腺:101.40 卵巣:186.30 精巣:26 心臓:38.30 骨格筋:60.30 食道:- 胃:106.20 腸:- 結腸:339.20     肝臓:52.80        肺:97.80    膀胱:- 腎臓:41.60 下垂体:- 甲状腺:- 副腎:50.80 膵臓:62.20 乳腺:492.50 唾液腺:-
GeneChip 子宮:5.93 胎盤:5.91 前立腺:6.66 卵巣:6.82 精巣:5.34 心臓:6.15 骨格筋:5.77 食道:6.06 胃:6.62 腸:6.57 結腸:6.48 肝臓:5.63 肺:7.03 膀胱:- 腎臓:5.33 下垂体:5.80 甲状腺:5.39 副腎:5.52 膵臓:5.44 乳腺:7.54 唾液腺:6.22
CAGE 子宮:2.95 胎盤:3.21 前立腺:3.51 卵巣:3.28 精巣:2.54 心臓:3.42 骨格筋:3.83 食道:3.00 胃:- 腸:3.02 結腸:3.32     肝臓:2.52    肺:4.35 膀胱:3.66 腎臓:2.17 下垂体:2.91 甲状腺:2.25 副腎:- 膵臓:3.02 乳腺:5.34 唾液腺:3.52
RNA-seq 子宮:- 胎盤:- 前立腺:1.46 卵巣:2.51 精巣:1.74 心臓:0.19 骨格筋:1.41 食道:- 胃:- 腸:- 結腸:0.88     肝臓:0.07        肺:1.66    膀胱:- 腎臓:1.17 下垂体:- 甲状腺:1.16 副腎:1.65 膵臓:- 乳腺:2.77 唾液腺:-

IDs

Refseq ID NM_001754
Gene ID 861
Unigene ID Hs.149261
Probe set ID 209360_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000159216
GTEx ID ENSG00000159216

オーソログ対応遺伝子

マウス[32]  NM_001111021, NM_001111022, NM_001111023, NM_009821
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1423235
1427868
1560822
1720541
7533526
7541640
7651838
7761424
7780150
7795214
7835892
7862156
7891692
7919324
8313895
8334990
8353289
8395054
8413232
8490181
8565077
8622667
8622955
8634147
8700862
8889548
9119228
9199349
9447981
9751710
10068652
10207087
10228168
10404214
10455134
10508512
10521447
10531362
10545320
10675041
10713153
10825294
10830953
10856244
10882117
11118213
11203699
11274169
11276260
11641401
11742995
11792409
11830488
11921279
11965546
11979742
11986950
12002768
12060124
12072207
12082641
12091359
12200707
12217689
12352981
12356919
12377125
12393286
12393523
12393679
12460926
12477932
12495904
12496475
12526921
12554803
12555067
12557226
12560229
12576332
12604126
12643014
12699896
12760263
12773394
12874780
12917624
12937148
14523475
14525764
14561740
14562119
14615365
14623259
14702039
14703694
14729951
14747476
14752096
14966519
14970218
15051730
15061191
15104277
15104290
15142876
15142881
15179033
15184985
15203865
15302935
15331439
15333839
15339695
15386419
15475366
15489901
15613106
15618958
15654961
15688019
15704129
15705784
15723339
15728845
15735013
15741216
15829516
15856017
15897867
15914564
15968309
15970674
15991223
16042694
16046550
16102112
16149049
16177090
16213368
16237704
16249223
16278392
16287839
16307024
16314494
16386788
16442267
16474840
16519819
16598304
16616331
16627249
16628190
16652140
16652147
16652416
16673018
16674921
16684349
16702405
16741927
16803898
16821265
16888092
16892559
16914570
16917507
16964375
17015828
17017876
17043020
17072347
17079875
17095626
17213321
17234761
17285576
17377532
17394134
17431401
17485549
17532767
17533375
17550866
17560011
17560331
17589498
17625612
17635584
17650443
17673463
17684492
17690704
17854666
17889709
17889714
17894555
17910630
17935781
17956600
17975013
17989718
17996649
18003885
18029348
18073335
18087673
18166807
18183572
18192504
18202228
18202291
18206538
18206548
18276842
18316480
18328148
18332109
18337762
18445843
18462252
18478040
18487507
18511808
18519037
18539581
18548094
18622412
18635414
18656694
18663147
18668679
18671852
18687517
18687690
18695000
18701449
18723428
18724045
18728978
18767145
18767146
18768464
18790797
18853425
18925961
18928518
18952841
19001502
19020999
19043539
19100510
19100516
19114653
19129484
19144660
19151769
19158815
19167608
19179469
19282830
19322201
19322702
19328795
19334039
19337732
19351817
19357396
19387465
19403666
19448675
19453261
19454010
19458628
19494111
19497860
19524548
19581587
19585539
19603429
19626042
19638627
19665068
19666867
19773259
19808697
19850737
19896186
19913121
19917773
19946261
19998443
20001241
20008790
20030931
20035012
20111069
20124335
20181616
20190817
20195544
20197715
20206228
20236534
20306249
20306685
20308320
20339092
20346360
20379614
20395453
20421268
20430957
20439113
20460523
20506188
20520634
20520637
20547749
20589720
20603019
20628086
20678218
20682397
20686504
20688956
20722699
20735389
20807887
20846103
20855863
20880116
20946940
20970160
21029724
21054152
21057539
21059642
21070662
21076613
21088106
21090242
21109770
21129147
21139048
21148331
21150319
21166663
21200020
21204219
21224468
21233836
21252065
21268063
21283084
21292764
21294243
21322790
21325596
21332713
21343560
21380778
21445863
21447743
21468021
21493867
21518930
21571218
21576367
21640801
21642993
21723253
21725049
21764752
21799513
21803869
21822204
21828118
21829377
21836606
21836608
21869842
21873977
21890473
21900195
22012064
22021368
22024923
22025082
22028862
22032690
22076464
22081516
22094587
22145956
22163048
22193545
22201794
22221250
22253733
22318203
22343733
22366949
22404039
22419089
22430633
22498736
22505724
22542470
22551552
22673192
22689058
22689681
22725134
22748822
22753902
22777353
22828445
22865593
22898599
22919028
22995345
23000965
23022380
23028138
23034403
23065512
23086478
23148227
23175372
23223432
23254331
23321257
23327922
23333304
23341344
23350231
23352661
23372166
23426948
23442798
23443342
23471304
23488608
23527860
23528260
23551011
23667531
23741012
23752268
23753029
23848403
23874874
23958918
23979164
24002588
24007691
24035334
24055056
24100448
24130502
24240203
24297870
24321385
24327541
24449215
24456692
24523240
24816145

遺伝子オントロジー  (GO ID)

Biological Process

GO:0048266  behavioral response to pain
GO:0007417  central nervous system development
GO:0060216  definitive hemopoiesis
GO:0035162  embryonic hemopoiesis
GO:0031069  hair follicle morphogenesis
GO:0030097  hemopoiesis
GO:0071425  hemopoietic stem cell proliferation
GO:0001701  in utero embryonic development
GO:0001889  liver development
GO:0030099  myeloid cell differentiation
GO:0002318  myeloid progenitor cell differentiation
GO:0030853  negative regulation of granulocyte differentiation
GO:0048935  peripheral nervous system neuron development
GO:0045766  positive regulation of angiogenesis
GO:0030854  positive regulation of granulocyte differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0071336  regulation of hair follicle cell proliferation
GO:0009966  regulation of signal transduction
GO:0001501  skeletal system development
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005604  basement membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0005509  calcium ion binding
GO:0003677  DNA binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding