tumor protein p63

詳細情報を見る

同義遺伝子名

P73L, Keratinocyte transcription factor KET, CUSP, TP63, EEC3, B(p51B), p73H, Chronic ulcerative stomatitis protein, Tumor protein p73-like, p51, OFC8, P63, SHFM4, TP73L, tumor protein p63, KET, RHS, tumor protein p73-like, B(p51A), P73H, LMS, p73L, Tumor protein 63

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:118.60 目:17.60 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:77.30 骨髄:- 脂肪:- 骨:- 皮膚:364.80
GeneChip 大脳:5.18 小脳:5.10 脳幹:5.24 脳梁:5.08 松果体:- 末梢神経:5.20 脊柱:5.21 網膜:- 目:- 動脈:5.13 静脈:5.15 リンパ節:5.22 末梢血:- 脾臓:5.11 胸腺:5.77 骨髄:5.08 脂肪:5.45 骨:- 皮膚:5.74
CAGE 大脳:0.12 小脳:- 脳幹:0.22 脳梁:0.24 松果体:0.48 末梢神経:- 脊柱:0.86 網膜:- 目:- 動脈:1.57 静脈:1.76 リンパ節:1.96 末梢血:- 脾臓:0 胸腺:2.76 骨髄:- 脂肪:1.99 骨:- 皮膚:-
RNA-seq 大脳:0 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.03 骨:- 皮膚:-
EST 子宮:- 胎盤:21.90 前立腺:101.40 卵巣:- 精巣:26 心臓:153.30 骨格筋:20.10 食道:- 胃:- 腸:- 結腸:8.50     肝臓:-        肺:24.40    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:4.92 胎盤:5.18 前立腺:5.49 卵巣:4.69 精巣:4.89 心臓:5.26 骨格筋:7.44 食道:6.42 胃:5.21 腸:5.48 結腸:5.38 肝臓:5.12 肺:5.16 膀胱:- 腎臓:5.23 下垂体:5.16 甲状腺:4.90 副腎:5.20 膵臓:5.31 乳腺:5.80 唾液腺:5.36
CAGE 子宮:1.81 胎盤:2.73 前立腺:3.06 卵巣:0.07 精巣:0.77 心臓:0 骨格筋:4.82 食道:4.20 胃:- 腸:0 結腸:0.04     肝臓:0    肺:1.27 膀胱:2.40 腎臓:0.58 下垂体:0.42 甲状腺:0.53 副腎:- 膵臓:0 乳腺:1.36 唾液腺:2.06
RNA-seq 子宮:- 胎盤:- 前立腺:0.30 卵巣:0 精巣:0.43 心臓:0 骨格筋:1.52 食道:- 胃:- 腸:- 結腸:0     肝臓:0        肺:0    膀胱:- 腎臓:0 下垂体:- 甲状腺:0.15 副腎:0 膵臓:- 乳腺:0.64 唾液腺:-

IDs

Refseq ID NM_001114982
Gene ID 8626
Unigene ID Hs.137569
Probe set ID 207382_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000073282
GTEx ID ENSG00000073282

オーソログ対応遺伝子

マウス[18]  NM_001127259, NM_001127260, NM_001127261, NM_001127262, NM_001127263, NM_001127264, NM_001127265, NM_011641
ラット[6]  NM_001127339, NM_001127341, NM_001127342, NM_001127343, NM_001127344, NM_019221, NM_001127265, NM_011641

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8695800
8889548
9405685
9618472
9662346
9662378
9703973
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007569  cell aging
GO:0034644  cellular response to UV
GO:0006338  chromatin remodeling
GO:0060197  cloacal septation
GO:0042771  DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0006978  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0007499  ectoderm and mesoderm interaction
GO:0030326  embryonic limb morphogenesis
GO:0010481  epidermal cell division
GO:0002064  epithelial cell development
GO:0001736  establishment of planar polarity
GO:0048807  female genitalia morphogenesis
GO:0031571  G1/S DNA damage checkpoint
GO:0031069  hair follicle morphogenesis
GO:0006917  induction of apoptosis
GO:0030216  keratinocyte differentiation
GO:0043616  keratinocyte proliferation
GO:0010259  multicellular organismal aging
GO:0043066  negative regulation of apoptosis
GO:0045617  negative regulation of keratinocyte differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0051402  neuron apoptosis
GO:0007219  Notch signaling pathway
GO:0042475  odontogenesis of dentine-containing tooth
GO:0030859  polarized epithelial cell differentiation
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0045747  positive regulation of Notch signaling pathway
GO:0045669  positive regulation of osteoblast differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0060513  prostatic bud formation
GO:0051289  protein homotetramerization
GO:0009954  proximal/distal pattern formation
GO:0043523  regulation of neuron apoptosis
GO:0010332  response to gamma radiation
GO:0010165  response to X-ray
GO:0001501  skeletal system development
GO:0048745  smooth muscle tissue development
GO:0060529  squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
GO:0048485  sympathetic nervous system development
GO:0060157  urinary bladder development

Cellular Component

GO:0000785  chromatin
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0030425  dendrite
GO:0005794  Golgi apparatus
GO:0000790  nuclear chromatin
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0003684  damaged DNA binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0003690  double-stranded DNA binding
GO:0042802  identical protein binding
GO:0046872  metal ion binding
GO:0002039  p53 binding
GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity