receptor-interacting serine-threonine kinase 2

詳細情報を見る

同義遺伝子名

RIP2, GIG30, Receptor-interacting protein 2, receptor-interacting serine-threonine kinase 2, RIP-like-interacting CLARP kinase, CCK, CARD-containing IL-1 beta ICE-kinase, RICK, RIP-2, CARDIAK, RIPK2, UNQ277/PRO314/PRO34092, CARD3

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:27.30 小脳:- 脳幹:- 脳梁:29.20 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:11.80 動脈:179.90 静脈:- リンパ節:50.60 末梢血:- 脾臓:37.80 胸腺:25.80 骨髄:- 脂肪:- 骨:12.80 皮膚:9.60
GeneChip 大脳:6.46 小脳:6.30 脳幹:6.55 脳梁:6.81 松果体:- 末梢神経:6.83 脊柱:7.19 網膜:- 目:- 動脈:6.83 静脈:7.30 リンパ節:6.79 末梢血:- 脾臓:6.89 胸腺:6.42 骨髄:6.83 脂肪:6.99 骨:- 皮膚:7.14
CAGE 大脳:2.64 小脳:- 脳幹:2.90 脳梁:3.04 松果体:2.21 末梢神経:- 脊柱:3.35 網膜:- 目:- 動脈:2.97 静脈:2.89 リンパ節:3.01 末梢血:- 脾臓:3.27 胸腺:2.25 骨髄:- 脂肪:3.18 骨:- 皮膚:-
RNA-seq 大脳:2.54 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.83 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.75 骨:- 皮膚:-
EST 子宮:27.30 胎盤:69.20 前立腺:33.80 卵巣:37.30 精巣:21.60 心臓:25.50 骨格筋:- 食道:- 胃:169.90 腸:32.40 結腸:25.40     肝臓:-        肺:44    膀胱:125.60 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:8.90 乳腺:55.80 唾液腺:-
GeneChip 子宮:6.94 胎盤:7.78 前立腺:7.24 卵巣:6.73 精巣:6.66 心臓:6.88 骨格筋:6.09 食道:6.69 胃:6.83 腸:6.82 結腸:6.76 肝臓:6.67 肺:7.30 膀胱:- 腎臓:6.47 下垂体:6.59 甲状腺:6.56 副腎:6.30 膵臓:7.23 乳腺:6.83 唾液腺:6.82
CAGE 子宮:2.92 胎盤:3.55 前立腺:2.87 卵巣:2.85 精巣:2.37 心臓:2.95 骨格筋:1.67 食道:2.82 胃:- 腸:2.46 結腸:2.63     肝臓:2.78    肺:3.31 膀胱:3.33 腎臓:2.73 下垂体:2.68 甲状腺:2.76 副腎:- 膵臓:2.48 乳腺:2.99 唾液腺:2.80
RNA-seq 子宮:- 胎盤:- 前立腺:2.75 卵巣:2.75 精巣:2.67 心臓:2.07 骨格筋:0.98 食道:- 胃:- 腸:- 結腸:2.74     肝臓:1.63        肺:3.97    膀胱:- 腎臓:2.24 下垂体:- 甲状腺:2.32 副腎:2.68 膵臓:- 乳腺:2.55 唾液腺:-

IDs

Refseq ID NM_003821
Gene ID 8767
Unigene ID Hs.103755
Probe set ID 209545_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000104312
GTEx ID ENSG00000104312

オーソログ対応遺伝子

マウス[2]  NM_138952
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0002250  adaptive immune response
GO:0006915  apoptosis
GO:0071223  cellular response to lipoteichoic acid
GO:0071224  cellular response to peptidoglycan
GO:0050830  defense response to Gram-positive bacterium
GO:0007249  I-kappaB kinase/NF-kappaB cascade
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0007254  JNK cascade
GO:0031663  lipopolysaccharide-mediated signaling pathway
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0043066  negative regulation of apoptosis
GO:0048011  nerve growth factor receptor signaling pathway
GO:0070427  nucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070431  nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0070423  nucleotide-binding oligomerization domain containing signaling pathway
GO:0046641  positive regulation of alpha-beta T cell proliferation
GO:0043065  positive regulation of apoptosis
GO:0032722  positive regulation of chemokine production
GO:0001961  positive regulation of cytokine-mediated signaling pathway
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0033091  positive regulation of immature T cell proliferation
GO:0032727  positive regulation of interferon-alpha production
GO:0032728  positive regulation of interferon-beta production
GO:0032729  positive regulation of interferon-gamma production
GO:0032735  positive regulation of interleukin-12 production
GO:0032743  positive regulation of interleukin-2 production
GO:0032755  positive regulation of interleukin-6 production
GO:0046330  positive regulation of JNK cascade
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0031398  positive regulation of protein ubiquitination
GO:0045627  positive regulation of T-helper 1 cell differentiation
GO:0002827  positive regulation of T-helper 1 type immune response
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0032760  positive regulation of tumor necrosis factor production
GO:0043330  response to exogenous dsRNA
GO:0070555  response to interleukin-1
GO:0070671  response to interleukin-12
GO:0070673  response to interleukin-18
GO:0007165  signal transduction
GO:0051403  stress-activated MAPK cascade
GO:0042098  T cell proliferation
GO:0050852  T cell receptor signaling pathway
GO:0034166  toll-like receptor 10 signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034146  toll-like receptor 5 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol

Molecular Function

GO:0005524  ATP binding
GO:0050700  CARD domain binding
GO:0030274  LIM domain binding
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0004674  protein serine/threonine kinase activity
GO:0004871  signal transducer activity