K(lysine) acetyltransferase 2B

詳細情報を見る

同義遺伝子名

GCN5, Histone acetyltransferase PCAF, GCN5L, GCN5L1, P/CAF, Histone acetylase PCAF, CAF, P300/CBP-associated factor, p300/CBP-associated factor, PCAF

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:53.30 小脳:25.20 脳幹:- 脳梁:29.20 松果体:- 末梢神経:92 脊柱:336.90 網膜:118.60 目:70.50 動脈:239.80 静脈:- リンパ節:50.60 末梢血:- 脾臓:56.70 胸腺:116 骨髄:39.40 脂肪:40.30 骨:- 皮膚:52.80
GeneChip 大脳:7.35 小脳:6.81 脳幹:7.61 脳梁:8.06 松果体:- 末梢神経:7.49 脊柱:8.03 網膜:- 目:- 動脈:6.58 静脈:6.33 リンパ節:6.76 末梢血:- 脾臓:7.01 胸腺:8.20 骨髄:8.03 脂肪:6.62 骨:- 皮膚:6.38
CAGE 大脳:3.91 小脳:- 脳幹:4.00 脳梁:4.27 松果体:3.42 末梢神経:- 脊柱:4.10 網膜:- 目:- 動脈:3.03 静脈:2.94 リンパ節:2.58 末梢血:- 脾臓:2.85 胸腺:2.91 骨髄:- 脂肪:3.05 骨:- 皮膚:-
RNA-seq 大脳:4.24 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.95 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:3.18 骨:- 皮膚:-
EST 子宮:9.10 胎盤:193.10 前立腺:56.30 卵巣:149.10 精巣:17.30 心臓:12.80 骨格筋:40.20 食道:- 胃:21.20 腸:32.40 結腸:17     肝臓:42.20        肺:53.80    膀胱:- 腎臓:20.80 下垂体:116 甲状腺:- 副腎:- 膵臓:62.20 乳腺:18.60 唾液腺:328.40
GeneChip 子宮:6.16 胎盤:6.23 前立腺:7.10 卵巣:6.17 精巣:3.94 心臓:7.11 骨格筋:7.95 食道:6.81 胃:6.41 腸:6.43 結腸:5.50 肝臓:7.16 肺:6.90 膀胱:- 腎臓:6.23 下垂体:6.32 甲状腺:6.85 副腎:5.62 膵臓:5.38 乳腺:5.97 唾液腺:7.72
CAGE 子宮:2.94 胎盤:3.05 前立腺:2.98 卵巣:2.70 精巣:1.73 心臓:3.31 骨格筋:3.00 食道:3.08 胃:- 腸:3.31 結腸:2.77     肝臓:2.78    肺:3.05 膀胱:2.66 腎臓:2.74 下垂体:2.74 甲状腺:3.13 副腎:- 膵臓:2.76 乳腺:2.79 唾液腺:3.21
RNA-seq 子宮:- 胎盤:- 前立腺:3.85 卵巣:3.35 精巣:2.82 心臓:4.70 骨格筋:4.09 食道:- 胃:- 腸:- 結腸:3.50     肝臓:3.26        肺:3.31    膀胱:- 腎臓:3.27 下垂体:- 甲状腺:4.02 副腎:2.96 膵臓:- 乳腺:4.02 唾液腺:-

IDs

Refseq ID NM_003884
Gene ID 8850
Unigene ID Hs.533055
Probe set ID 203845_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000114166
GTEx ID ENSG00000114166

オーソログ対応遺伝子

マウス[2]  NM_001190846, NM_020005
ラット[2]  NM_001190846, NM_020005

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1602151
8684459
8945521
9223281
9267036
9296499
9346901
9445475
9659901
9674425
9687573
9710619
9722949
9733796
9742083
9744860
9809067
9824164
9880483
9885574
9891054
9892017
10022868
10025406
10207070
10318892
10365964
10373431
10545121
10567539
10619020
10747963
10753971
10766811
10777539
10777601
10779504
10811635
10852958
10891508
10944526
10958685
10966108
11046145
11058129
11118214
11163245
11250901
11304541
11404076
11463815
11486036
11509179
11509661
11547919
11564863
11568182
11581372
11607033
11689696
11741939
11748222
11818576
11830591
11864601
11931765
11937047
11956210
11994312
12015309
12032084
12068014
12082103
12101239
12154097
12297501
12374802
12391158
12419806
12435739
12477932
12486002
12501250
12601814
12660246
12758070
12813456
12815053
12878208
12887892
12888487
12917345
12937166
14500836
14581481
14614455
14645221
14657027
14661947
14747462
14752096
14767476
14769800
14980312
15005629
15009097
15023334
15044952
15123636
15153330
15171254
15183343
15273251
15286281
15350211
15454570
15482860
15489334
15509593
15572685
15604093
15611041
15616580
15647279
15719065
15834423
15987677
15992539
15994459
16035254
16046164
16050810
16055439
16060659
16096645
16122695
16135803
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16285943
16322561
16332960
16362936
16415179
16537920
16543236
16613856
16630892
16678111
16696975
16728408
16829519
16838299
16878158
16904069
16917507
17141982
17158926
17168834
17189186
17226766
17293853
17301242
17317667
17444627
17468105
17475621
17602165
17611664
17643375
17707232
17726049
17882273
17884818
17908689
17964260
17977830
17982102
18089809
18247445
18250157
18400184
18443043
18497079
18504427
18574470
18586263
18599479
18660489
18663001
18669648
18697823
18710935
18782771
18834332
18838386
18950845
18957410
18987336
19015268
19056724
19084499
19158279
19176998
19188449
19223581
19249677
19276081
19303849
19351588
19407811
19470756
19483727
19525977
19526283
19589782
19716452
19773423
19812265
19950226
19961954
19996091
20107328
20213728
20224553
20227660
20363750
20364308
20379614
20484414
20530585
20589832
20604809
20651253
20663877
20663886
20870727
20889312
20935208
21060154
21062767
21079652
21108945
21148070
21209460
21413932
21444723
21447625
21489275
21775285
21987584
22055187
22100137
22174411
22219331
22335196
22384255
22547391
22709982
22713239
23001180
23044042
23095762
23441852
23591450
23595990
23643089
23667505
23714681
23826228
23981651
24009623
24013724
24037888
24098694
24129567

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007050  cell cycle arrest
GO:0032869  cellular response to insulin stimulus
GO:0006338  chromatin remodeling
GO:0010467  gene expression
GO:0043966  histone H3 acetylation
GO:0018076  N-terminal peptidyl-lysine acetylation
GO:0008285  negative regulation of cell proliferation
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0007219  Notch signaling pathway
GO:0018394  peptidyl-lysine acetylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006473  protein amino acid acetylation
GO:0010835  regulation of protein amino acid ADP-ribosylation
GO:0006360  transcription from RNA polymerase I promoter
GO:0006361  transcription initiation from RNA polymerase I promoter
GO:0006367  transcription initiation from RNA polymerase II promoter
GO:0019048  virus-host interaction

Cellular Component

GO:0031672  A band
GO:0042641  actomyosin
GO:0005671  Ada2/Gcn5/Ada3 transcription activator complex
GO:0031674  I band
GO:0000776  kinetochore
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0000125  PCAF complex

Molecular Function

GO:0016407  acetyltransferase activity
GO:0004861  cyclin-dependent protein kinase inhibitor activity
GO:0004402  histone acetyltransferase activity
GO:0042826  histone deacetylase binding
GO:0004468  lysine N-acetyltransferase activity
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0003713  transcription coactivator activity
GO:0003712  transcription cofactor activity
GO:0008134  transcription factor binding