sequestosome 1

詳細情報を見る

同義遺伝子名

Sequestosome-1, ORCA, A170, OSIL, Paget disease of bone 3, SQSTM1, Ubiquitin-binding protein p62, EBI3-associated protein of 60 kDa, sequestosome 1, p62B, oxidative stress induced like, ZIP3, PDB3, EBIAP

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:275 小脳:503.80 脳幹:- 脳梁:291.60 松果体:148.30 末梢神経:368.10 脊柱:449.20 網膜:- 目:634.70 動脈:269.80 静脈:799.80 リンパ節:131.40 末梢血:783.40 脾臓:453.80 胸腺:219 骨髄:944.70 脂肪:726 骨:499 皮膚:360
GeneChip 大脳:8.26 小脳:8.59 脳幹:8.39 脳梁:8.47 松果体:- 末梢神経:8.72 脊柱:8.49 網膜:- 目:- 動脈:8.87 静脈:8.86 リンパ節:8.59 末梢血:- 脾臓:8.47 胸腺:8.03 骨髄:7.66 脂肪:9.01 骨:- 皮膚:8.50
CAGE 大脳:5.06 小脳:- 脳幹:5.07 脳梁:5.29 松果体:5.14 末梢神経:- 脊柱:5.22 網膜:- 目:- 動脈:6.06 静脈:5.73 リンパ節:5.39 末梢血:- 脾臓:5.24 胸腺:4.97 骨髄:- 脂肪:6.09 骨:- 皮膚:-
RNA-seq 大脳:3.78 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:6.11 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:6.70 骨:- 皮膚:-
EST 子宮:446.50 胎盤:750.50 前立腺:360.50 卵巣:149.10 精巣:216.30 心臓:178.80 骨格筋:361.60 食道:342.80 胃:169.90 腸:453.60 結腸:305.30     肝臓:358.90        肺:366.60    膀胱:1256.10 腎臓:259.90 下垂体:116 甲状腺:3766.20 副腎:1218.90 膵臓:569 乳腺:529.70 唾液腺:656.80
GeneChip 子宮:8.77 胎盤:9.93 前立腺:8.82 卵巣:8.87 精巣:7.76 心臓:8.81 骨格筋:9.79 食道:8.80 胃:8.45 腸:8.52 結腸:8.32 肝臓:8.61 肺:8.75 膀胱:- 腎臓:8.47 下垂体:8.57 甲状腺:9.47 副腎:9.20 膵臓:8.03 乳腺:8.97 唾液腺:8.67
CAGE 子宮:5.58 胎盤:6.38 前立腺:5.84 卵巣:5.67 精巣:5.10 心臓:6.04 骨格筋:6.54 食道:5.64 胃:- 腸:5.28 結腸:5.56     肝臓:5.91    肺:5.91 膀胱:6.06 腎臓:5.67 下垂体:4.90 甲状腺:6.22 副腎:- 膵臓:5.63 乳腺:6.36 唾液腺:5.71
RNA-seq 子宮:- 胎盤:- 前立腺:7.14 卵巣:4.79 精巣:4.71 心臓:5.66 骨格筋:8.66 食道:- 胃:- 腸:- 結腸:6.04     肝臓:5.75        肺:6.42    膀胱:- 腎臓:6.19 下垂体:- 甲状腺:7.35 副腎:5.45 膵臓:- 乳腺:6.54 唾液腺:-

IDs

Refseq ID NM_003900
Gene ID 8878
Unigene ID Hs.437277
Probe set ID 201471_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000161011
GTEx ID ENSG00000161011

オーソログ対応遺伝子

マウス[1]  NM_011018
ラット[1]  NM_175843

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8551575
8618896
8650207
8702753
8910285
9184228
9252186
9566925
9762895
10022904
10356400
10362795
10708586
10747026
10776788
11244088
11447312
11473345
11563677
11755531
11786419
11852044
11981755
11992264
12034707
12242277
12374763
12431995
12471037
12477932
12700667
12727313
12787561
12813044
12857745
12857950
12869526
12887891
14584883
14676191
14692700
14702039
14702098
15125799
15143057
15146436
15158159
15164150
15176995
15207768
15340068
15489334
15493999
15592455
15647816
15721744
15761153
15765181
15802564
15840729
15870274
15911346
15953362
16011831
16079148
16083285
16129434
16159877
16169070
16189514
16196087
16252010
16286508
16335966
16344560
16405664
16565220
16574459
16630834
16691492
16751776
16793543
16820172
16861740
16874300
16964243
16997282
17052185
17065558
17081983
17120186
17187080
17203973
17229007
17237936
17314511
17580304
17685470
17898222
17931355
17932931
18083104
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18174161
18296712
18379439
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18442140
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18624398
18653543
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19398892
19427028
19481605
19557423
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19615732
19780870
19812211
19816510
19822672
19850743
19850933
19903815
19931284
20010802
20018885
20061786
20061800
20098416
20103647
20168092
20200946
20204693
20230821
20357094
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20417604
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22017874
22053931
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22118674
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22190034
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22286270
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22320446
22322858
22411133
22434781
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22505724
22525272
22565157
22674379
22714671
22728060
22792322
22797925
22835604
22841931
22863883
22939629
22941224
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23000965
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24220190
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24619419
24642144
24654937
24664425
24667411
24769000
24769734
24778252

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006914  autophagy
GO:0030154  cell differentiation
GO:0016197  endosome transport
GO:0016236  macroautophagy
GO:0043066  negative regulation of apoptosis
GO:0048011  nerve growth factor receptor signaling pathway
GO:0043065  positive regulation of apoptosis
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0051291  protein heterooligomerization
GO:0008104  protein localization
GO:0043122  regulation of I-kappaB kinase/NF-kappaB cascade
GO:0046578  regulation of Ras protein signal transduction
GO:0006950  response to stress
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0016235  aggresome
GO:0005776  autophagic vacuole
GO:0000932  cytoplasmic mRNA processing body
GO:0031410  cytoplasmic vesicle
GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0005770  late endosome
GO:0005764  lysosome
GO:0005654  nucleoplasm
GO:0000407  pre-autophagosomal structure

Molecular Function

GO:0042802  identical protein binding
GO:0070530  K63-linked polyubiquitin binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0019901  protein kinase binding
GO:0005080  protein kinase C binding
GO:0004674  protein serine/threonine kinase activity
GO:0030971  receptor tyrosine kinase binding
GO:0042169  SH2 domain binding
GO:0043130  ubiquitin binding
GO:0008270  zinc ion binding