B-cell CLL/lymphoma 10

詳細情報を見る

同義遺伝子名

B-cell lymphoma/leukemia 10, mE10, CARMEN, Cellular-E10, CLAP, CARD-like apoptotic protein, CIPER, c-E10, Mammalian CARD-containing adapter molecule E10, Cellular homolog of vCARMEN, Bcl-10, cCARMEN, hCLAP, BCL10, B-cell CLL/lymphoma 10, CARD-containing molecule enhancing NF-kappa-B

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:10.70 小脳:- 脳幹:- 脳梁:29.20 松果体:- 末梢神経:61.30 脊柱:- 網膜:- 目:- 動脈:179.90 静脈:66.60 リンパ節:70.80 末梢血:18.20 脾臓:18.90 胸腺:- 骨髄:39.40 脂肪:- 骨:- 皮膚:9.60
GeneChip 大脳:5.23 小脳:5.27 脳幹:5.10 脳梁:5.37 松果体:- 末梢神経:5.54 脊柱:5.58 網膜:- 目:- 動脈:6.07 静脈:5.96 リンパ節:6.58 末梢血:- 脾臓:7.05 胸腺:6.62 骨髄:5.68 脂肪:6.18 骨:- 皮膚:6.54
CAGE 大脳:2.82 小脳:- 脳幹:2.80 脳梁:3.01 松果体:2.83 末梢神経:- 脊柱:3.05 網膜:- 目:- 動脈:3.52 静脈:3.57 リンパ節:4.03 末梢血:- 脾臓:3.87 胸腺:3.67 骨髄:- 脂肪:3.82 骨:- 皮膚:-
RNA-seq 大脳:1.69 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:3.29 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:2.67 骨:- 皮膚:-
EST 子宮:27.30 胎盤:10.90 前立腺:- 卵巣:74.50 精巣:43.30 心臓:12.80 骨格筋:- 食道:- 胃:21.20 腸:32.40 結腸:25.40     肝臓:21.10        肺:24.40    膀胱:125.60 腎臓:10.40 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:102.20 唾液腺:-
GeneChip 子宮:6.77 胎盤:6.18 前立腺:7.03 卵巣:6.67 精巣:5.83 心臓:5.81 骨格筋:5.21 食道:7.24 胃:6.53 腸:6.18 結腸:7.20 肝臓:5.68 肺:6.88 膀胱:- 腎臓:6.22 下垂体:5.36 甲状腺:6.35 副腎:6.04 膵臓:5.21 乳腺:6.60 唾液腺:5.88
CAGE 子宮:3.75 胎盤:3.37 前立腺:3.52 卵巣:3.38 精巣:3.29 心臓:3.30 骨格筋:2.33 食道:4.27 胃:- 腸:4.21 結腸:4.01     肝臓:3.22    肺:4.00 膀胱:3.66 腎臓:3.40 下垂体:2.95 甲状腺:3.32 副腎:- 膵臓:3.20 乳腺:3.99 唾液腺:3.30
RNA-seq 子宮:- 胎盤:- 前立腺:2.83 卵巣:2.66 精巣:2.73 心臓:1.60 骨格筋:1.42 食道:- 胃:- 腸:- 結腸:2.77     肝臓:1.90        肺:3.52    膀胱:- 腎臓:2.97 下垂体:- 甲状腺:2.20 副腎:2.67 膵臓:- 乳腺:2.95 唾液腺:-

IDs

Refseq ID NM_003921
Gene ID 8915
Unigene ID Hs.193516
Probe set ID 205263_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000142867
GTEx ID ENSG00000142867

オーソログ対応遺伝子

マウス[3]  NM_009740
ラット[1]  NM_031328

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0002250  adaptive immune response
GO:0008219  cell death
GO:0006921  cell structure disassembly during apoptosis
GO:0006968  cellular defense response
GO:0071260  cellular response to mechanical stimulus
GO:0007249  I-kappaB kinase/NF-kappaB cascade
GO:0016064  immunoglobulin mediated immune response
GO:0045087  innate immune response
GO:0042226  interleukin-6 biosynthetic process
GO:0042109  lymphotoxin A biosynthetic process
GO:0002906  negative regulation of mature B cell apoptosis
GO:0001843  neural tube closure
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045416  positive regulation of interleukin-8 biosynthetic process
GO:0032765  positive regulation of mast cell cytokine production
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0042327  positive regulation of phosphorylation
GO:0031398  positive regulation of protein ubiquitination
GO:0050870  positive regulation of T cell activation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051260  protein homooligomerization
GO:0051259  protein oligomerization
GO:0050856  regulation of T cell receptor signaling pathway
GO:0042221  response to chemical stimulus
GO:0009620  response to fungus
GO:0002237  response to molecule of bacterial origin
GO:0050852  T cell receptor signaling pathway
GO:0002224  toll-like receptor signaling pathway

Cellular Component

GO:0032449  CBM complex
GO:0005737  cytoplasm
GO:0005881  cytoplasmic microtubule
GO:0005829  cytosol
GO:0001772  immunological synapse
GO:0046696  lipopolysaccharide receptor complex
GO:0005764  lysosome
GO:0045121  membrane raft
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0043234  protein complex
GO:0042101  T cell receptor complex

Molecular Function

GO:0019899  enzyme binding
GO:0019209  kinase activator activity
GO:0019900  kinase binding
GO:0051059  NF-kappaB binding
GO:0002020  protease binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0043422  protein kinase B binding
GO:0019901  protein kinase binding
GO:0043621  protein self-association
GO:0003713  transcription coactivator activity
GO:0008134  transcription factor binding
GO:0043130  ubiquitin binding
GO:0031625  ubiquitin protein ligase binding