slit homolog 2 (Drosophila)

詳細情報を見る

同義遺伝子名

Slit-2, SLIT2, Slit homolog 2 protein precursor, slit (Drosophila) homolog 2, FLJ14420, SLIL3, slit homolog 2 (Drosophila)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST nodata
GeneChip 大脳:7.33 小脳:5.57 脳幹:6.49 脳梁:6.46 松果体:- 末梢神経:8.84 脊柱:6.66 網膜:- 目:- 動脈:8.25 静脈:8.47 リンパ節:6.68 末梢血:- 脾臓:8.50 胸腺:5.91 骨髄:5.70 脂肪:7.49 骨:- 皮膚:7
CAGE 大脳:0.98 小脳:- 脳幹:0.50 脳梁:0.39 松果体:0.36 末梢神経:- 脊柱:0.40 網膜:- 目:- 動脈:1.16 静脈:0.59 リンパ節:0.39 末梢血:- 脾臓:2.60 胸腺:0.12 骨髄:- 脂肪:0.90 骨:- 皮膚:-
RNA-seq 大脳:1.75 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:2.42 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.60 骨:- 皮膚:-
EST nodata
GeneChip 子宮:8.46 胎盤:6.51 前立腺:8.03 卵巣:7.69 精巣:5.80 心臓:7.43 骨格筋:6.21 食道:7.28 胃:7.75 腸:6.89 結腸:7.29 肝臓:5.54 肺:9.86 膀胱:- 腎臓:7.71 下垂体:7.44 甲状腺:8.01 副腎:9.39 膵臓:5.91 乳腺:8.07 唾液腺:6.77
CAGE 子宮:2.11 胎盤:1.05 前立腺:1.66 卵巣:1.29 精巣:0.62 心臓:0.72 骨格筋:0.24 食道:1.36 胃:- 腸:0.69 結腸:1.17     肝臓:0.14    肺:2.57 膀胱:1.49 腎臓:1.50 下垂体:1.08 甲状腺:0.64 副腎:- 膵臓:0 乳腺:0.90 唾液腺:0.62
RNA-seq 子宮:- 胎盤:- 前立腺:3.37 卵巣:1.83 精巣:2.03 心臓:1.50 骨格筋:0.58 食道:- 胃:- 腸:- 結腸:2.95     肝臓:0.26        肺:4.32    膀胱:- 腎臓:1.92 下垂体:- 甲状腺:2.39 副腎:1.73 膵臓:- 乳腺:2.20 唾液腺:-

IDs

Refseq ID NM_004787
Gene ID 9353
Unigene ID -
Probe set ID 209897_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000145147
GTEx ID ENSG00000145147

オーソログ対応遺伝子

マウス[4]  NM_178804
ラット[1]  NM_022632

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0048846  axon extension involved in axon guidance
GO:0007411  axon guidance
GO:0048754  branching morphogenesis of a tube
GO:0002042  cell migration involved in sprouting angiogenesis
GO:0016337  cell-cell adhesion
GO:0071504  cellular response to heparin
GO:0032870  cellular response to hormone stimulus
GO:0021834  chemorepulsion involved in embryonic olfactory bulb interneuron migration
GO:0021836  chemorepulsion involved in postnatal olfactory bulb interneuron migration
GO:0021972  corticospinal neuron axon guidance through the spinal cord
GO:0033563  dorsal/ventral axon guidance
GO:0001701  in utero embryonic development
GO:0050929  induction of negative chemotaxis
GO:0060763  mammary duct terminal end bud growth
GO:0001656  metanephros development
GO:0008045  motor axon guidance
GO:0050919  negative chemotaxis
GO:0030837  negative regulation of actin filament polymerization
GO:0030308  negative regulation of cell growth
GO:0030336  negative regulation of cell migration
GO:0008285  negative regulation of cell proliferation
GO:0070100  negative regulation of chemokine-mediated signaling pathway
GO:0010596  negative regulation of endothelial cell migration
GO:0010629  negative regulation of gene expression
GO:0010593  negative regulation of lamellipodium assembly
GO:0002689  negative regulation of leukocyte chemotaxis
GO:0090027  negative regulation of monocyte chemotaxis
GO:0090024  negative regulation of neutrophil chemotaxis
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0051058  negative regulation of small GTPase mediated signal transduction
GO:0014912  negative regulation of smooth muscle cell migration
GO:0043116  negative regulation of vascular permeability
GO:0043065  positive regulation of apoptosis
GO:0050772  positive regulation of axonogenesis
GO:0051414  response to cortisol stimulus
GO:0031290  retinal ganglion cell axon guidance
GO:0001657  ureteric bud development

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005509  calcium ion binding
GO:0045499  chemorepellent activity
GO:0005095  GTPase inhibitor activity
GO:0008201  heparin binding
GO:0043237  laminin-1 binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0043394  proteoglycan binding
GO:0048495  Roundabout binding