activin A receptor type II-like 1

同義遺伝子名

TSR-I, TGF-B superfamily receptor type I, ALK-1, ORW2, activin A receptor type II-like 1, ALK1, Activin receptor-like kinase 1, HHT, ACVRL1, SKR3, HHT2, ACVRLK1

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:3.60

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:41.10

動脈:-

静脈:533.20

リンパ節:-

末梢血:18.20

脾臓:18.90

胸腺:12.90

骨髄:-

脂肪:40.30

骨:12.80

皮膚:19.20

GeneChip

大脳:4.93

小脳:4.83

脳幹:5.09

脳梁:4.59

松果体:-

末梢神経:4.70

脊柱:4.65

網膜:-

目:-

動脈:5.32

静脈:5.47

リンパ節:5.22

末梢血:-

脾臓:5.15

胸腺:4.79

骨髄:5.12

脂肪:5.53

骨:-

皮膚:5.40

CAGE

大脳:1.73

小脳:-

脳幹:1.84

脳梁:1.88

松果体:1.70

末梢神経:-

脊柱:1.42

網膜:-

目:-

動脈:2.39

静脈:2.95

リンパ節:2.75

末梢血:-

脾臓:3.05

胸腺:1.12

骨髄:-

脂肪:3.65

骨:-

皮膚:-

RNA-seq

大脳:1.64

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:3.02

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:4.05

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:51

前立腺:214

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:24.40

膀胱:-

腎臓:31.20

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:65.10

唾液腺:-

GeneChip

子宮:5.15

胎盤:5.19

前立腺:5.10

卵巣:4.88

精巣:4.70

心臓:5.31

骨格筋:5.22

食道:5.01

胃:5.17

腸:5.41

結腸:5.65

肝臓:4.85

肺:6.23

膀胱:-

腎臓:5.19

下垂体:4.93

甲状腺:4.99

副腎:5.33

膵臓:5.01

乳腺:5.07

唾液腺:5.13

CAGE

子宮:3.14

胎盤:4.10

前立腺:2.99

卵巣:2.27

精巣:1.34

心臓:3.08

骨格筋:2.81

食道:2.92

胃:-

腸:2.51

結腸:3.22

肝臓:1.60

肺:4.47

膀胱:2.67

腎臓:3.00

下垂体:1.25

甲状腺:2.75

副腎:-

膵臓:2.18

乳腺:3.16

唾液腺:2.06

RNA-seq

子宮:-

胎盤:-

前立腺:2.10

卵巣:1.90

精巣:1.84

心臓:2.19

骨格筋:0.00

食道:-

胃:-

腸:-

結腸:3.28

肝臓:1.15

肺:4.78

膀胱:-

腎臓:3.23

下垂体:-

甲状腺:3.17

副腎:3.87

膵臓:-

乳腺:3.14

唾液腺:-

IDs

Refseq ID	NM_001077401
Gene ID	94
Unigene ID	Hs.591026
Probe set ID	210838_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000139567
GTEx ID	ENSG00000139567

オーソログ対応遺伝子

マウス[1]	NM_009612
ラット [0]

染色体

12q13.13 [52,300,692 - 52,317,145]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000333	Activin type II receptor
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0060840	artery development
GO:0008015	blood circulation
GO:0002043	blood vessel endothelial cell proliferation during sprouting angiogenesis
GO:0001955	blood vessel maturation
GO:0001974	blood vessel remodeling
GO:0030509	BMP signaling pathway
GO:0001701	in utero embryonic development
GO:0001946	lymphangiogenesis
GO:0060836	lymphatic endothelial cell differentiation
GO:0043537	negative regulation of blood vessel endothelial cell migration
GO:0007162	negative regulation of cell adhesion
GO:0030308	negative regulation of cell growth
GO:0030336	negative regulation of cell migration
GO:0008285	negative regulation of cell proliferation
GO:0045602	negative regulation of endothelial cell differentiation
GO:0010596	negative regulation of endothelial cell migration
GO:0001937	negative regulation of endothelial cell proliferation
GO:0051895	negative regulation of focal adhesion formation
GO:0030513	positive regulation of BMP signaling pathway
GO:0032332	positive regulation of chondrocyte differentiation
GO:0045603	positive regulation of endothelial cell differentiation
GO:0001938	positive regulation of endothelial cell proliferation
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006468	protein amino acid phosphorylation
GO:0051291	protein heterooligomerization
GO:0008217	regulation of blood pressure
GO:0043535	regulation of blood vessel endothelial cell migration
GO:0006275	regulation of DNA replication
GO:0001936	regulation of endothelial cell proliferation
GO:0006355	regulation of transcription, DNA-dependent
GO:0007165	signal transduction
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0060841	venous blood vessel development
GO:0035313	wound healing, spreading of epidermal cells

Cellular Component

GO:0043025	cell soma
GO:0009986	cell surface
GO:0030425	dendrite
GO:0005887	integral to plasma membrane

Molecular Function

GO:0048185	activin binding
GO:0016361	activin receptor activity, type I
GO:0005524	ATP binding
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0004674	protein serine/threonine kinase activity
GO:0004702	receptor signaling protein serine/threonine kinase activity
GO:0046332	SMAD binding
GO:0050431	transforming growth factor beta binding
GO:0005024	transforming growth factor beta receptor activity
GO:0005025	transforming growth factor beta receptor activity, type I
GO:0004675	transmembrane receptor protein serine/threonine kinase activity

activin A receptor type II-like 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function