CD74 molecule, major histocompatibility complex, class II invariant chain

詳細情報を見る

同義遺伝子名

Ii, HLA-DR antigens-associated invariant chain, DHLAG, Ia-GAMMA, HLADG, protein 41, Ia antigen-associated invariant chain, CD74, CD74 antigen

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:46.20 小脳:- 脳幹:- 脳梁:- 松果体:445 末梢神経:184 脊柱:- 網膜:- 目:229.20 動脈:629.50 静脈:- リンパ節:262.90 末梢血:236.80 脾臓:378.10 胸腺:51.50 骨髄:196.80 脂肪:322.70 骨:1074.80 皮膚:172.80
GeneChip 大脳:9.17 小脳:7.66 脳幹:9.97 脳梁:10.56 松果体:- 末梢神経:11.41 脊柱:11.07 網膜:- 目:- 動脈:10.78 静脈:10.50 リンパ節:12.25 末梢血:- 脾臓:12.30 胸腺:11.26 骨髄:10.78 脂肪:11.48 骨:- 皮膚:10.45
CAGE 大脳:6.28 小脳:- 脳幹:7.05 脳梁:7.44 松果体:6.31 末梢神経:- 脊柱:7.49 網膜:- 目:- 動脈:7.65 静脈:8.77 リンパ節:8.73 末梢血:- 脾臓:8.88 胸腺:8.16 骨髄:- 脂肪:7.68 骨:- 皮膚:-
RNA-seq 大脳:2.34 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:0.00 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:0.11 骨:- 皮膚:-
EST 子宮:182.30 胎盤:43.70 前立腺:112.60 卵巣:223.60 精巣:8.70 心臓:140.50 骨格筋:180.80 食道:- 胃:106.20 腸:64.80 結腸:271.30     肝臓:42.20        肺:444.80    膀胱:- 腎臓:20.80 下垂体:- 甲状腺:327.50 副腎:152.40 膵臓:1120.30 乳腺:408.90 唾液腺:1642
GeneChip 子宮:10.27 胎盤:9.02 前立腺:9.90 卵巣:10.55 精巣:8.32 心臓:10.46 骨格筋:8.63 食道:10.24 胃:10.95 腸:10.64 結腸:10.72 肝臓:10.06 肺:12.48 膀胱:- 腎臓:10.78 下垂体:9.94 甲状腺:10.64 副腎:10.68 膵臓:9.57 乳腺:11.01 唾液腺:10.73
CAGE 子宮:7.23 胎盤:6.31 前立腺:7.41 卵巣:7.04 精巣:6.11 心臓:7.01 骨格筋:6.16 食道:6.77 胃:- 腸:8.07 結腸:7.05     肝臓:6.97    肺:8.63 膀胱:7.03 腎臓:8.13 下垂体:6.24 甲状腺:6.85 副腎:- 膵臓:6.49 乳腺:6.73 唾液腺:7.60
RNA-seq 子宮:- 胎盤:- 前立腺:0.00 卵巣:0.06 精巣:2.70 心臓:1.28 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:0.18     肝臓:1.23        肺:3.25    膀胱:- 腎臓:0.00 下垂体:- 甲状腺:0.00 副腎:2.81 膵臓:- 乳腺:0.00 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0019883  antigen processing and presentation of endogenous antigen
GO:0019886  antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0008283  cell proliferation
GO:0051085  chaperone mediated protein folding requiring cofactor
GO:0006952  defense response
GO:0016064  immunoglobulin mediated immune response
GO:0006886  intracellular protein transport
GO:0043066  negative regulation of apoptosis
GO:0043518  negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0002906  negative regulation of mature B cell apoptosis
GO:0002792  negative regulation of peptide secretion
GO:0045581  negative regulation of T cell differentiation
GO:0045060  negative thymic T cell selection
GO:0030890  positive regulation of B cell proliferation
GO:0001961  positive regulation of cytokine-mediated signaling pathway
GO:0002606  positive regulation of dendritic cell antigen processing and presentation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0048146  positive regulation of fibroblast proliferation
GO:0060907  positive regulation of macrophage cytokine production
GO:0090023  positive regulation of neutrophil chemotaxis
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0045582  positive regulation of T cell differentiation
GO:0002830  positive regulation of T-helper 2 type immune response
GO:0045059  positive thymic T cell selection
GO:0001516  prostaglandin biosynthetic process
GO:0006461  protein complex assembly
GO:0043030  regulation of macrophage activation
GO:0007165  signal transduction
GO:0045058  T cell selection

Cellular Component

GO:0009986  cell surface
GO:0030669  clathrin-coated endocytic vesicle membrane
GO:0030666  endocytic vesicle membrane
GO:0012507  ER to Golgi transport vesicle membrane
GO:0009897  external side of plasma membrane
GO:0000139  Golgi membrane
GO:0016021  integral to membrane
GO:0005622  intracellular
GO:0043202  lysosomal lumen
GO:0005765  lysosomal membrane
GO:0042613  MHC class II protein complex
GO:0005771  multivesicular body
GO:0005886  plasma membrane
GO:0032588  trans-Golgi network membrane
GO:0030658  transport vesicle membrane
GO:0005773  vacuole

Molecular Function

GO:0001540  beta-amyloid binding
GO:0019955  cytokine binding
GO:0004896  cytokine receptor activity
GO:0042802  identical protein binding
GO:0042289  MHC class II protein binding
GO:0050998  nitric-oxide synthase binding