histone deacetylase 4

詳細情報を見る

同義遺伝子名

histone deacetylase 4, Histone deacetylase 4, HD4, KIAA0288, HDAC4, HDAC-A, HDACA, HA6116

正常組織・臓器 40分類
細胞株・初代培養細胞・成体組織・胎児組織 (FANTOM5 CAGE)

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:125.60

小脳:75.60

脳幹:-

脳梁:29.20

松果体:296.70

末梢神経:122.70

脊柱:-

網膜:-

目:58.80

動脈:329.70

静脈:66.60

リンパ節:131.40

末梢血:54.70

脾臓:75.60

胸腺:38.70

骨髄:19.70

脂肪:80.70

骨:12.80

皮膚:24

GeneChip

大脳:5.99

小脳:6

脳幹:5.72

脳梁:6.03

松果体:-

末梢神経:6.14

脊柱:5.87

網膜:-

目:-

動脈:5.94

静脈:5.25

リンパ節:5.58

末梢血:-

脾臓:5.71

胸腺:7.27

骨髄:5.77

脂肪:5.41

骨:-

皮膚:6.13

CAGE

大脳:2.63

小脳:-

脳幹:2.74

脳梁:2.80

松果体:2.44

末梢神経:-

脊柱:2.62

網膜:-

目:-

動脈:2.68

静脈:3.03

リンパ節:2.59

末梢血:-

脾臓:2.66

胸腺:3.18

骨髄:-

脂肪:3.10

骨:-

皮膚:-

RNA-seq

大脳:1.93

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:1.72

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:1.40

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:127.60

胎盤:94.70

前立腺:22.50

卵巣:111.80

精巣:160.10

心臓:191.60

骨格筋:40.20

食道:685.60

胃:127.50

腸:64.80

結腸:67.80

肝臓:116.10

肺:97.80

膀胱:-

腎臓:83.20

下垂体:116

甲状腺:-

副腎:457.10

膵臓:97.80

乳腺:65.10

唾液腺:328.40

GeneChip

子宮:6.44

胎盤:4.30

前立腺:6.33

卵巣:6.37

精巣:5.75

心臓:5.30

骨格筋:7.57

食道:5.94

胃:5.90

腸:6.06

結腸:6.14

肝臓:4.58

肺:5.07

膀胱:-

腎臓:5.44

下垂体:6.55

甲状腺:6.07

副腎:6.38

膵臓:4.98

乳腺:5.87

唾液腺:4.68

CAGE

子宮:3.49

胎盤:2.20

前立腺:3.15

卵巣:2.94

精巣:3.41

心臓:2.40

骨格筋:4.52

食道:3.02

胃:-

腸:2.83

結腸:3.27

肝臓:2.19

肺:2.69

膀胱:3.34

腎臓:2.14

下垂体:3.00

甲状腺:2.55

副腎:-

膵臓:2.66

乳腺:2.53

唾液腺:2.31

RNA-seq

子宮:-

胎盤:-

前立腺:2.68

卵巣:2.20

精巣:2.08

心臓:1.46

骨格筋:4.19

食道:-

胃:-

腸:-

結腸:2.75

肝臓:1.01

肺:1.27

膀胱:-

腎臓:1.54

下垂体:-

甲状腺:2.08

副腎:1.62

膵臓:-

乳腺:1.73

唾液腺:-

IDs

Refseq ID	NM_006037
Gene ID	9759
Unigene ID	Hs.205163
Probe set ID	204225_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000068024
GTEx ID	ENSG00000068024

オーソログ対応遺伝子

マウス[1]	NM_207225
ラット[1]	NM_207225

染色体

2q37.3 [239,969,864 - 240,323,348]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR017320	Histone deacetylase class II, eukaryotic
IPR000286	Histone deacetylase superfamily

遺伝子オントロジー (GO ID)

Biological Process

GO:0042113	B cell activation
GO:0030183	B cell differentiation
GO:0014898	cardiac muscle hypertrophy in response to stress
GO:0006338	chromatin remodeling
GO:0016575	histone deacetylation
GO:0070932	histone H3 deacetylation
GO:0070933	histone H4 deacetylation
GO:0006954	inflammatory response
GO:0008285	negative regulation of cell proliferation
GO:0045820	negative regulation of glycolysis
GO:0010832	negative regulation of myotube differentiation
GO:0045668	negative regulation of osteoblast differentiation
GO:0043433	negative regulation of transcription factor activity
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0007399	nervous system development
GO:0002076	osteoblast development
GO:0034983	peptidyl-lysine deacetylation
GO:0008284	positive regulation of cell proliferation
GO:0033235	positive regulation of protein sumoylation
GO:0051091	positive regulation of transcription factor activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
GO:0043393	regulation of protein binding
GO:0014894	response to denervation involved in regulation of muscle adaptation
GO:0042493	response to drug
GO:0070555	response to interleukin-1
GO:0001501	skeletal system development
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0031672	A band
GO:0042641	actomyosin
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0000118	histone deacetylase complex
GO:0031594	neuromuscular junction
GO:0005634	nucleus
GO:0017053	transcriptional repressor complex
GO:0030018	Z disc

Molecular Function

GO:0044212	DNA regulatory region binding
GO:0004407	histone deacetylase activity
GO:0042826	histone deacetylase binding
GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046969	NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970	NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0030955	potassium ion binding
GO:0005515	protein binding
GO:0033558	protein deacetylase activity
GO:0019901	protein kinase binding
GO:0043565	sequence-specific DNA binding
GO:0033613	transcription activator binding
GO:0003714	transcription corepressor activity
GO:0008134	transcription factor binding
GO:0070491	transcription repressor binding
GO:0008270	zinc ion binding

histone deacetylase 4

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function