cyclin-dependent kinase 1

詳細情報を見る

同義遺伝子名

Cyclin-dependent kinase 1, p34 protein kinase, DKFZp686L20222, CDK1, CDC2, cell division cycle 2, G1 to S and G2 to M, MGC111195, Cell division control protein 2 homolog

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:4.70 小脳:- 脳幹:- 脳梁:29.20 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:30 静脈:66.60 リンパ節:404.40 末梢血:- 脾臓:- 胸腺:25.80 骨髄:- 脂肪:40.30 骨:- 皮膚:9.60
GeneChip 大脳:4.67 小脳:4.62 脳幹:4.68 脳梁:4.53 松果体:- 末梢神経:4.39 脊柱:4.49 網膜:- 目:- 動脈:4.60 静脈:4.71 リンパ節:5.02 末梢血:- 脾臓:4.58 胸腺:7.61 骨髄:6.81 脂肪:4.78 骨:- 皮膚:4.92
CAGE 大脳:0.24 小脳:- 脳幹:0.56 脳梁:0.43 松果体:0.43 末梢神経:- 脊柱:0.88 網膜:- 目:- 動脈:0.87 静脈:2.39 リンパ節:2.29 末梢血:- 脾臓:2.23 胸腺:4.39 骨髄:- 脂肪:1.60 骨:- 皮膚:-
RNA-seq 大脳:0.57 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:1.96 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:1.46 骨:- 皮膚:-
EST 子宮:72.90 胎盤:- 前立腺:- 卵巣:- 精巣:60.60 心臓:51.10 骨格筋:- 食道:342.80 胃:- 腸:32.40 結腸:17     肝臓:63.30        肺:29.30    膀胱:125.60 腎臓:10.40 下垂体:116 甲状腺:- 副腎:50.80 膵臓:- 乳腺:158 唾液腺:-
GeneChip 子宮:5.27 胎盤:5.05 前立腺:4.38 卵巣:4.78 精巣:6.38 心臓:4.64 骨格筋:4.68 食道:5.34 胃:5.09 腸:5.19 結腸:5.44 肝臓:4.40 肺:4.68 膀胱:- 腎臓:4.59 下垂体:5.04 甲状腺:4.51 副腎:4.45 膵臓:4.91 乳腺:4.68 唾液腺:4.63
CAGE 子宮:1.31 胎盤:2.62 前立腺:0.66 卵巣:0.42 精巣:2.79 心臓:0.78 骨格筋:0.09 食道:2.98 胃:- 腸:2.20 結腸:2.49     肝臓:0.14    肺:1.68 膀胱:0.40 腎臓:1.24 下垂体:0.50 甲状腺:0.32 副腎:- 膵臓:0 乳腺:1.68 唾液腺:0.83
RNA-seq 子宮:- 胎盤:- 前立腺:1.22 卵巣:0.88 精巣:4.11 心臓:0.65 骨格筋:0.00 食道:- 胃:- 腸:- 結腸:1.36     肝臓:0.15        肺:2.02    膀胱:- 腎臓:1.82 下垂体:- 甲状腺:1.17 副腎:1.22 膵臓:- 乳腺:1.27 唾液腺:-

IDs

Refseq ID NM_001786
Gene ID 983
Unigene ID Hs.334562
Probe set ID 203214_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000170312
GTEx ID ENSG00000170312

オーソログ対応遺伝子

マウス[1]  NM_007659
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

914146
1310466
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0000186  activation of MAPKK activity
GO:0031145  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0006915  apoptosis
GO:0007411  axon guidance
GO:0007569  cell aging
GO:0051301  cell division
GO:0016477  cell migration
GO:0070301  cellular response to hydrogen peroxide
GO:0007098  centrosome cycle
GO:0030261  chromosome condensation
GO:0006281  DNA repair
GO:0006260  DNA replication
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0000082  G1/S transition of mitotic cell cycle
GO:0000086  G2/M transition of mitotic cell cycle
GO:0045087  innate immune response
GO:0008286  insulin receptor signaling pathway
GO:0000165  MAPKKK cascade
GO:0000226  microtubule cytoskeleton organization
GO:0007067  mitosis
GO:0000278  mitotic cell cycle
GO:0007095  mitotic cell cycle G2/M transition DNA damage checkpoint
GO:0007077  mitotic nuclear envelope disassembly
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0043066  negative regulation of apoptosis
GO:0048011  nerve growth factor receptor signaling pathway
GO:0031100  organ regeneration
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0045740  positive regulation of DNA replication
GO:0010628  positive regulation of gene expression
GO:0045931  positive regulation of mitotic cell cycle
GO:0033160  positive regulation of protein import into nucleus, translocation
GO:0051437  positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0007344  pronuclear fusion
GO:0006461  protein complex assembly
GO:0034501  protein localization to kinetochore
GO:0007265  Ras protein signal transduction
GO:0045995  regulation of embryonic development
GO:0014038  regulation of Schwann cell differentiation
GO:0000083  regulation of transcription involved in G1/S-phase of mitotic cell cycle
GO:0051439  regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0014823  response to activity
GO:0014075  response to amine stimulus
GO:0048678  response to axon injury
GO:0046686  response to cadmium ion
GO:0046688  response to copper ion
GO:0042493  response to drug
GO:0045471  response to ethanol
GO:0014070  response to organic cyclic substance
GO:0009636  response to toxin
GO:0007264  small GTPase mediated signal transduction
GO:0051403  stress-activated MAPK cascade
GO:0034166  toll-like receptor 10 signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034146  toll-like receptor 5 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway
GO:0055015  ventricular cardiac muscle cell development

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005815  microtubule organizing center
GO:0030496  midbody
GO:0005739  mitochondrion
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005876  spindle microtubule

Molecular Function

GO:0005524  ATP binding
GO:0030332  cyclin binding
GO:0004693  cyclin-dependent protein kinase activity
GO:0035173  histone kinase activity
GO:0030544  Hsp70 protein binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0008353  RNA polymerase II carboxy-terminal domain kinase activity