proprotein convertase subtilisin/kexin type 9

詳細情報を見る

同義遺伝子名

MGC47409, Neural apoptosis-regulated convertase 1, proprotein convertase subtilisin/kexin type 9, Proprotein convertase PC9, Narc1, Pcsk9, NARC-1, AI747682, HCHOLA3, FH3, Subtilisin/kexin-like protease PC9, AI415265

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:5.20 小脳:128.90 脳幹:- 脳梁:- 松果体:- 末梢神経:57.30 脊柱:- 網膜:- 目:7.60 動脈:- 静脈:- リンパ節:32.40 末梢血:- 脾臓:13.20 胸腺:- 骨髄:12.80 脂肪:- 骨:- 皮膚:15.80
GeneChip nodata
CAGE 大脳:0 小脳:- 脳幹:0.09 脳梁:- 松果体:- 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0.14 静脈:- リンパ節:0 末梢血:- 脾臓:0 胸腺:0 骨髄:- 脂肪:- 骨:0 皮膚:0.15
RNA-seq 大脳:1.46 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:13.80 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:32.70 腸:37 結腸:88.10     肝臓:63.40        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip nodata
CAGE 子宮:0.31 胎盤:0.68 前立腺:0 卵巣:0.45 精巣:0 心臓:- 骨格筋:- 食道:- 胃:1.07 腸:3.14 結腸:2.19     肝臓:4.35    肺:0 膀胱:0.33 腎臓:- 下垂体:0.29 甲状腺:- 副腎:0.14 膵臓:0.84 乳腺:0 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:5.31        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0032869  cellular response to insulin stimulus
GO:0009267  cellular response to starvation
GO:0042632  cholesterol homeostasis
GO:0008203  cholesterol metabolic process
GO:0006917  induction of apoptosis
GO:0006629  lipid metabolic process
GO:0042157  lipoprotein metabolic process
GO:0032802  low-density lipoprotein receptor catabolic process
GO:0032799  low-density lipoprotein receptor metabolic process
GO:0007041  lysosomal transport
GO:0043086  negative regulation of catalytic activity
GO:0010989  negative regulation of low-density lipoprotein particle clearance
GO:0001920  negative regulation of receptor recycling
GO:0030182  neuron differentiation
GO:0006644  phospholipid metabolic process
GO:0043525  positive regulation of neuron apoptosis
GO:0002092  positive regulation of receptor internalization
GO:0016540  protein autoprocessing
GO:0016485  protein processing
GO:0006508  proteolysis
GO:0032803  regulation of low-density lipoprotein receptor catabolic process
GO:0043523  regulation of neuron apoptosis
GO:0010469  regulation of receptor activity
GO:0008202  steroid metabolic process
GO:0006641  triglyceride metabolic process

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005769  early endosome
GO:0005783  endoplasmic reticulum
GO:0005768  endosome
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005794  Golgi apparatus
GO:0005770  late endosome
GO:0005764  lysosome
GO:0048471  perinuclear region of cytoplasm
GO:0005791  rough endoplasmic reticulum

Molecular Function

GO:0034185  apolipoprotein binding
GO:0034190  apolipoprotein receptor binding
GO:0016787  hydrolase activity
GO:0042802  identical protein binding
GO:0030169  low-density lipoprotein binding
GO:0050750  low-density lipoprotein receptor binding
GO:0008233  peptidase activity
GO:0043621  protein self-association
GO:0004252  serine-type endopeptidase activity
GO:0008236  serine-type peptidase activity
GO:0019871  sodium channel inhibitor activity
GO:0034189  very-low-density lipoprotein binding
GO:0070326  very-low-density lipoprotein receptor binding