c-abl oncogene 1, receptor tyrosine kinase

詳細情報を見る

同義遺伝子名

AI325092, Abelson murine leukemia viral oncogene homolog 1, c-Abl, v-abl Abelson murine leukemia oncogene 1, Abl, Proto-oncogene tyrosine-protein kinase ABL1, Abl1, E430008G22Rik, c-ABL, MGC117749

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:15.60 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:94.60 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:7.86 小脳:7.65 脳幹:- 脳梁:- 松果体:- 末梢神経:7.32 脊柱:8.29 網膜:7.79 目:8.36 動脈:- 静脈:9.28 リンパ節:8.40 末梢血:- 脾臓:8.77 胸腺:- 骨髄:8.22 脂肪:8.10 骨:8.15 皮膚:8.01
CAGE 大脳:3.47 小脳:- 脳幹:3.45 脳梁:- 松果体:- 末梢神経:- 脊柱:3.55 網膜:- 目:- 動脈:3.33 静脈:- リンパ節:3.38 末梢血:- 脾臓:3.33 胸腺:3.81 骨髄:- 脂肪:- 骨:3.54 皮膚:3.59
RNA-seq 大脳:4.26 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:11.50 精巣:- 心臓:55.80 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:8.10 下垂体:- 甲状腺:- 副腎:- 膵臓:18.80 乳腺:9.80 唾液腺:-
GeneChip 子宮:9.43 胎盤:8.37 前立腺:8.58 卵巣:9.05 精巣:7.88 心臓:8.40 骨格筋:8.47 食道:- 胃:8.39 腸:8.72 結腸:- 肝臓:7.24 肺:8.61 膀胱:9.08 腎臓:7.95 下垂体:7.90 甲状腺:- 副腎:8.97 膵臓:7.65 乳腺:8.44 唾液腺:8.72
CAGE 子宮:3.90 胎盤:3.33 前立腺:3.26 卵巣:3.79 精巣:4.51 心臓:- 骨格筋:- 食道:- 胃:2.79 腸:3.95 結腸:3.88     肝臓:3.12    肺:3.79 膀胱:3.96 腎臓:- 下垂体:3.52 甲状腺:- 副腎:3.65 膵臓:3.83 乳腺:3.48 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:3.85 食道:- 胃:- 腸:- 結腸:-     肝臓:2.77        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_009594
Gene ID 11350
Unigene ID Mm.131825
Probe set ID 1423999_at  [Mouse430_2]
Ensembl ID ENSMUSG00000026842

オーソログ対応遺伝子

ヒト[2]  NM_005157, NM_007313
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

211509
1315305
1316195
1362103
1571536
1673105
1676977
1682866
1887331
1889815
1901427
1904008
1914521
1916246
1968040
1970329
1971250
2065352
2065353
2155783
2168550
2183226
2404338
2406516
2554496
2575583
2895600
2906048
3283651
3317402
3443101
3512096
3594566
4022013
6243819
6257398
6293057
6306446
6319018
7121606
7490102
7537265
7542761
7664083
7665185
7671324
7750469
7766993
7774911
7862448
7893599
8075499
8088777
8093609
8438166
8449489
8486356
8510937
8535092
8570653
8597644
8605874
8612582
8635998
8700526
8747926
8755665
8756350
8799160
8806812
8854872
8861907
8978305
9011744
9109492
9143501
9144171
9279386
9315092
9356459
9393882
9583675
9590288
9603926
9636171
9808572
9872323
9883720
9986727
10072522
10322452
10349636
10373409
10391678
10450747
10498879
10536058
10567556
10674025
10700189
10797576
10805805
10823839
10825157
10896159
10922068
10945997
10967110
10988075
10995551
11003672
11031258
11040211
11042159
11076861
11114734
11120811
11163214
11217851
11274764
11279004
11309382
11390389
11413193
11475331
11494128
11702780
11809706
11847100
11864995
11955625
12021275
12032333
12070014
12130510
12149518
12167702
12379650
12466851
12469118
12477932
12520002
12531427
12569093
12626632
12672821
12748290
12777400
12796783
12893824
12928501
12944467
12950161
14519491
14610273
14681479
14691545
14993293
15148308
15226421
15226823
15254900
15289456
15378021
15489334
15543137
15632178
15657060
15735695
15767668
15782199
15961388
15987940
16076903
16091742
16115887
16141072
16141073
16297667
16377569
16380437
16602821
16611216
16713579
16798735
16867995
16899465
16901904
16945999
16998483
17101133
17173068
17229817
17254966
17363963
17620332
17626041
17686996
17718712
17881279
17898204
17928439
17967808
18025176
18305217
18362889
18538733
18624912
18632630
18704194
18725623
18765637
18799693
18813851
18827006
19077273
19098427
19228876
19299624
19306298
19414610
19470755
19542491
19560455
19563810
19571320
19679652
19690215
19805123
19805386
19823681
19829692
19833721
20080568
20150913
20181697
20220006
20417104
20563669
20697350
20798688
20823226
20837657
20937825
20980600
21081495
21212806
21249431
21263154
21267068
21320496
21364621
21527514
21625221
21690296
21693657
21764785
21900236
21900237
22000011
22143492
22199356
22234689
22252550
22396406
22408137
22560297
22665498
22729085
22733220
22738912
22889954
22938163
22940072
22975324
23100514
23160449
23287417
23515840
23660976
23821550
23840065
23950180
24056763
24112389
24242069
24357321
24401847
24657654

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0006915  apoptosis
GO:0006914  autophagy
GO:0007155  cell adhesion
GO:0006975  DNA damage induced protein phosphorylation
GO:0042770  DNA damage response, signal transduction
GO:0006281  DNA repair
GO:0006897  endocytosis
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0016310  phosphorylation
GO:0048008  platelet-derived growth factor receptor signaling pathway
GO:0043065  positive regulation of apoptosis
GO:0051353  positive regulation of oxidoreductase activity
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0051726  regulation of cell cycle
GO:0006974  response to DNA damage stimulus

Cellular Component

GO:0031252  cell leading edge
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0005739  mitochondrion
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0001726  ruffle

Molecular Function

GO:0005524  ATP binding
GO:0003677  DNA binding
GO:0016301  kinase activity
GO:0000287  magnesium ion binding
GO:0030145  manganese ion binding
GO:0046872  metal ion binding
GO:0051019  mitogen-activated protein kinase binding
GO:0004715  non-membrane spanning protein tyrosine kinase activity
GO:0000166  nucleotide binding
GO:0070064  proline-rich region binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0019904  protein domain specific binding
GO:0004672  protein kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0017124  SH3 domain binding
GO:0019905  syntaxin binding
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups