activin A receptor, type 1

同義遺伝子名

activin A receptor, type 1, ALK2, Acvr, Activin receptor type-1 precursor, SKR1, TSK-7L, Acvr1, Tgfb1, Acvrlk2, Activin receptor type I, TGF-B superfamily receptor type I, TSR-I, Tsk7L, Alk8, ActR-I, Alk-2, ActRIA, ACTR-I, Serine/threonine-protein kinase receptor R1, D330013D15Rik

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:48.60

小脳:147.40

脳幹:63.60

脳梁:-

松果体:-

末梢神経:76.40

脊柱:-

網膜:32.10

目:30.40

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:12.50

皮膚:31.70

GeneChip

大脳:8.07

小脳:7.75

脳幹:-

脳梁:-

松果体:-

末梢神経:7.51

脊柱:7.46

網膜:6.85

目:7.38

動脈:-

静脈:9.34

リンパ節:7.21

末梢血:-

脾臓:5.70

胸腺:-

骨髄:5.84

脂肪:8.21

骨:7.04

皮膚:7.91

CAGE

大脳:2.82

小脳:-

脳幹:2.04

脳梁:-

松果体:-

末梢神経:-

脊柱:2.58

網膜:-

目:-

動脈:3.10

静脈:-

リンパ節:2.45

末梢血:-

脾臓:0.93

胸腺:0.67

骨髄:-

脂肪:-

骨:1.84

皮膚:3.41

RNA-seq

大脳:5.87

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:41.40

前立腺:30.90

卵巣:-

精巣:7.40

心臓:-

骨格筋:-

食道:-

胃:-

腸:73.90

結腸:70.50

肝臓:-

肺:20.10

膀胱:-

腎臓:-

下垂体:167.90

甲状腺:-

副腎:-

膵臓:9.40

乳腺:9.80

唾液腺:-

GeneChip

子宮:8.02

胎盤:8.96

前立腺:8.18

卵巣:9.04

精巣:5.59

心臓:8.08

骨格筋:8.59

食道:-

胃:7.85

腸:7.78

結腸:-

肝臓:7.80

肺:8.31

膀胱:8.67

腎臓:6.72

下垂体:8.49

甲状腺:-

副腎:10.28

膵臓:6.25

乳腺:8.31

唾液腺:7.12

CAGE

子宮:2.18

胎盤:2.21

前立腺:1.97

卵巣:3.15

精巣:1.18

心臓:-

骨格筋:-

食道:-

胃:2.52

腸:2.03

結腸:2.03

肝臓:2.48

肺:2.46

膀胱:2.58

腎臓:-

下垂体:2.63

甲状腺:-

副腎:3.76

膵臓:1.30

乳腺:2.41

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:2.68

食道:-

胃:-

腸:-

結腸:-

肝臓:2.41

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_001110204
Gene ID	11477
Unigene ID	Mm.6890
Probe set ID	1448460_at [Mouse430_2]
Ensembl ID	ENSMUSG00000026836

オーソログ対応遺伝子

ヒト[1]	NM_001105, NM_001111067
ラット [0]

染色体

2C1.1 [58,241,055 - 58,419,568]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000333	Activin type II receptor
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0032924	activin receptor signaling pathway
GO:0003289	atrial septum primum morphogenesis
GO:0030509	BMP signaling pathway
GO:0060923	cardiac muscle cell fate commitment
GO:0007368	determination of left/right symmetry
GO:0009790	embryonic development
GO:0003143	embryonic heart tube morphogenesis
GO:0000082	G1/S transition of mitotic cell cycle
GO:0007369	gastrulation
GO:0001702	gastrulation with mouth forming second
GO:0007281	germ cell development
GO:0007507	heart development
GO:0001701	in utero embryonic development
GO:0007498	mesoderm development
GO:0001707	mesoderm formation
GO:0003183	mitral valve morphogenesis
GO:0032926	negative regulation of activin receptor signaling pathway
GO:0009968	negative regulation of signal transduction
GO:0001755	neural crest cell migration
GO:0060389	pathway-restricted SMAD protein phosphorylation
GO:0001569	patterning of blood vessels
GO:0018107	peptidyl-threonine phosphorylation
GO:0060037	pharyngeal system development
GO:0016310	phosphorylation
GO:0030501	positive regulation of bone mineralization
GO:0045669	positive regulation of osteoblast differentiation
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006468	protein amino acid phosphorylation
GO:0030278	regulation of ossification
GO:0051145	smooth muscle cell differentiation
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0001655	urogenital system development

Cellular Component

GO:0048179	activin receptor complex
GO:0045177	apical part of cell
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane

Molecular Function

GO:0048185	activin binding
GO:0016361	activin receptor activity, type I
GO:0005524	ATP binding
GO:0019838	growth factor binding
GO:0016301	kinase activity
GO:0046872	metal ion binding
GO:0000166	nucleotide binding
GO:0042803	protein homodimerization activity
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004702	receptor signaling protein serine/threonine kinase activity
GO:0046332	SMAD binding
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0050431	transforming growth factor beta binding
GO:0005024	transforming growth factor beta receptor activity
GO:0005025	transforming growth factor beta receptor activity, type I
GO:0004675	transmembrane receptor protein serine/threonine kinase activity

activin A receptor, type 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function