activin receptor IIA

同義遺伝子名

activin receptor IIA, Acvr2a, Acvr2, ACTR-IIA, Activin receptor type 2A precursor, tActRII, Activin receptor type IIA, ActRIIa

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:43.40

小脳:18.40

脳幹:31.80

脳梁:-

松果体:-

末梢神経:-

脊柱:141.90

網膜:-

目:53.20

動脈:337.60

静脈:-

リンパ節:-

末梢血:-

脾臓:13.20

胸腺:49.40

骨髄:25.60

脂肪:-

骨:37.60

皮膚:23.80

GeneChip

大脳:6.97

小脳:5.84

脳幹:-

脳梁:-

松果体:-

末梢神経:6.93

脊柱:5.67

網膜:6.10

目:6.76

動脈:-

静脈:6.60

リンパ節:5.38

末梢血:-

脾臓:5.51

胸腺:-

骨髄:5.13

脂肪:6.34

骨:5.25

皮膚:6.65

CAGE

大脳:2.80

小脳:-

脳幹:2.31

脳梁:-

松果体:-

末梢神経:-

脊柱:2.40

網膜:-

目:-

動脈:2.96

静脈:-

リンパ節:2.91

末梢血:-

脾臓:1.36

胸腺:1.26

骨髄:-

脂肪:-

骨:1.97

皮膚:3.62

RNA-seq

大脳:1.34

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:13.80

前立腺:-

卵巣:23

精巣:14.80

心臓:55.80

骨格筋:-

食道:-

胃:-

腸:-

結腸:35.20

肝臓:9.10

肺:90.40

膀胱:-

腎臓:16.10

下垂体:-

甲状腺:-

副腎:-

膵臓:9.40

乳腺:75.10

唾液腺:-

GeneChip

子宮:6.08

胎盤:6.76

前立腺:5.82

卵巣:6

精巣:8.20

心臓:6.22

骨格筋:7.19

食道:-

胃:6.94

腸:7

結腸:-

肝臓:6.80

肺:6.28

膀胱:6.20

腎臓:6.63

下垂体:5.80

甲状腺:-

副腎:5.86

膵臓:6.53

乳腺:6.31

唾液腺:5.93

CAGE

子宮:2.94

胎盤:2.59

前立腺:2.31

卵巣:2.78

精巣:3.16

心臓:-

骨格筋:-

食道:-

胃:2.66

腸:3.11

結腸:3.13

肝臓:3.21

肺:3.10

膀胱:2.59

腎臓:-

下垂体:2.75

甲状腺:-

副腎:2.45

膵臓:3.53

乳腺:2.90

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.79

食道:-

胃:-

腸:-

結腸:-

肝臓:2.24

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_007396
Gene ID	11480
Unigene ID	Mm.314338
Probe set ID	1451004_at [Mouse430_2]
Ensembl ID	ENSMUSG00000052155

オーソログ対応遺伝子

ヒト[1]	NM_001616
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000333	Activin type II receptor
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0032924	activin receptor signaling pathway
GO:0009952	anterior/posterior pattern formation
GO:0030509	BMP signaling pathway
GO:0007368	determination of left/right symmetry
GO:0048706	embryonic skeletal system development
GO:0001702	gastrulation with mouth forming second
GO:0008584	male gonad development
GO:0007498	mesoderm development
GO:0043084	penile erection
GO:0016310	phosphorylation
GO:0032927	positive regulation of activin receptor signaling pathway
GO:0030501	positive regulation of bone mineralization
GO:0045648	positive regulation of erythrocyte differentiation
GO:0046881	positive regulation of follicle-stimulating hormone secretion
GO:0045669	positive regulation of osteoblast differentiation
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0030510	regulation of BMP signaling pathway
GO:0050999	regulation of nitric-oxide synthase activity
GO:0009966	regulation of signal transduction
GO:0060011	Sertoli cell proliferation
GO:0042713	sperm ejaculation
GO:0007283	spermatogenesis
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway

Cellular Component

GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0034673	inhibin-betaglycan-ActRII complex
GO:0016021	integral to membrane
GO:0016020	membrane

Molecular Function

GO:0048185	activin binding
GO:0017002	activin receptor activity
GO:0016362	activin receptor activity, type II
GO:0005524	ATP binding
GO:0015026	coreceptor activity
GO:0019838	growth factor binding
GO:0034711	inhibin binding
GO:0016301	kinase activity
GO:0046872	metal ion binding
GO:0000166	nucleotide binding
GO:0030165	PDZ domain binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0043621	protein self-association
GO:0004674	protein serine/threonine kinase activity
GO:0004702	receptor signaling protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0005024	transforming growth factor beta receptor activity
GO:0004675	transmembrane receptor protein serine/threonine kinase activity

activin receptor IIA

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function