activin A receptor, type II-like 1

同義遺伝子名

TSR-I, TGF-B superfamily receptor type I, Acvrlk1, ALK-1, activin A receptor, type II-like 1, activin receptor-like kinase-1, Activin receptor-like kinase 1, Alk-1, AI115505, Alk1, SKR3, AI427544, Acvrl1

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:-

小脳:-

脳幹:63.60

脳梁:-

松果体:-

末梢神経:38.20

脊柱:-

網膜:32.10

目:-

動脈:-

静脈:-

リンパ節:32.40

末梢血:-

脾臓:-

胸腺:39.50

骨髄:25.60

脂肪:-

骨:37.60

皮膚:79.20

GeneChip

大脳:5.64

小脳:5.47

脳幹:-

脳梁:-

松果体:-

末梢神経:5.51

脊柱:5.78

網膜:4.75

目:5.36

動脈:-

静脈:6.76

リンパ節:7.26

末梢血:-

脾臓:6.73

胸腺:-

骨髄:6.66

脂肪:6.91

骨:6.02

皮膚:5.86

CAGE

大脳:1.29

小脳:-

脳幹:1.41

脳梁:-

松果体:-

末梢神経:-

脊柱:1.85

網膜:-

目:-

動脈:2.36

静脈:-

リンパ節:1.28

末梢血:-

脾臓:1.52

胸腺:0.27

骨髄:-

脂肪:-

骨:1.97

皮膚:2.22

RNA-seq

大脳:5.31

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:87.20

胎盤:55.20

前立腺:-

卵巣:11.50

精巣:7.40

心臓:37.20

骨格筋:106.50

食道:-

胃:-

腸:-

結腸:88.10

肝臓:18.10

肺:70.30

膀胱:-

腎臓:8.10

下垂体:155

甲状腺:-

副腎:-

膵臓:-

乳腺:19.60

唾液腺:54

GeneChip

子宮:7.26

胎盤:8.95

前立腺:6.05

卵巣:6.61

精巣:4.99

心臓:7.15

骨格筋:6.97

食道:-

胃:6.48

腸:6.26

結腸:-

肝臓:5.81

肺:10.53

膀胱:6.89

腎臓:6.34

下垂体:5.51

甲状腺:-

副腎:6.02

膵臓:6.10

乳腺:6.61

唾液腺:5.88

CAGE

子宮:2.74

胎盤:2.76

前立腺:1.51

卵巣:2.27

精巣:0

心臓:-

骨格筋:-

食道:-

胃:2.16

腸:1.70

結腸:1.93

肝臓:0.47

肺:4.45

膀胱:2.82

腎臓:-

下垂体:1.48

甲状腺:-

副腎:2.02

膵臓:2.19

乳腺:2.35

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:3.16

食道:-

胃:-

腸:-

結腸:-

肝臓:1.68

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_009612
Gene ID	11482
Unigene ID	Mm.279542
Probe set ID	1451604_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000000530

オーソログ対応遺伝子

ヒト[2]	NM_000020, NM_001077401
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0032924	activin receptor signaling pathway
GO:0001525	angiogenesis
GO:0060840	artery development
GO:0008015	blood circulation
GO:0048514	blood vessel morphogenesis
GO:0001974	blood vessel remodeling
GO:0030509	BMP signaling pathway
GO:0042118	endothelial cell activation
GO:0001701	in utero embryonic development
GO:0001946	lymphangiogenesis
GO:0060836	lymphatic endothelial cell differentiation
GO:0043537	negative regulation of blood vessel endothelial cell migration
GO:0007162	negative regulation of cell adhesion
GO:0030308	negative regulation of cell growth
GO:0030336	negative regulation of cell migration
GO:0008285	negative regulation of cell proliferation
GO:0045602	negative regulation of endothelial cell differentiation
GO:0010596	negative regulation of endothelial cell migration
GO:0001937	negative regulation of endothelial cell proliferation
GO:0051895	negative regulation of focal adhesion formation
GO:0016310	phosphorylation
GO:0030513	positive regulation of BMP signaling pathway
GO:0045603	positive regulation of endothelial cell differentiation
GO:0001938	positive regulation of endothelial cell proliferation
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006468	protein amino acid phosphorylation
GO:0051291	protein heterooligomerization
GO:0008217	regulation of blood pressure
GO:0006355	regulation of transcription, DNA-dependent
GO:0007165	signal transduction
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0060841	venous blood vessel development
GO:0035313	wound healing, spreading of epidermal cells

Cellular Component

GO:0043025	cell soma
GO:0009986	cell surface
GO:0030425	dendrite
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane

Molecular Function

GO:0048185	activin binding
GO:0016361	activin receptor activity, type I
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0046872	metal ion binding
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0019901	protein kinase binding
GO:0004674	protein serine/threonine kinase activity
GO:0004702	receptor signaling protein serine/threonine kinase activity
GO:0046332	SMAD binding
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0050431	transforming growth factor beta binding
GO:0005024	transforming growth factor beta receptor activity
GO:0005025	transforming growth factor beta receptor activity, type I
GO:0004675	transmembrane receptor protein serine/threonine kinase activity

activin A receptor, type II-like 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function