angiotensin II receptor, type 1a

詳細情報を見る

同義遺伝子名

AT2R1A, Agtr-1a, AT1A, AT2R1, AT1a, angiotensin II receptor, type 1a, Agtr1a, Agtr1, MGC37610, Angtr-1a, Type-1A angiotensin II receptor, AG2S, AT1, 1810074K20Rik, AI551199

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:5.20 小脳:73.70 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:47.30 網膜:- 目:- 動脈:253.20 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:29.60 骨髄:- 脂肪:- 骨:- 皮膚:39.60
GeneChip nodata
CAGE 大脳:0.24 小脳:- 脳幹:0.50 脳梁:- 松果体:- 末梢神経:- 脊柱:0.17 網膜:- 目:- 動脈:2.37 静脈:- リンパ節:1.78 末梢血:- 脾臓:3.36 胸腺:0 骨髄:- 脂肪:- 骨:2.93 皮膚:1.86
RNA-seq 大脳:1.04 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:13.80 前立腺:- 卵巣:- 精巣:- 心臓:130.20 骨格筋:- 食道:- 胃:- 腸:- 結腸:35.20     肝臓:45.30        肺:10    膀胱:264.70 腎臓:40.30 下垂体:- 甲状腺:- 副腎:2546.70 膵臓:9.40 乳腺:19.60 唾液腺:-
GeneChip nodata
CAGE 子宮:2.30 胎盤:1.73 前立腺:3.38 卵巣:1.88 精巣:3.74 心臓:- 骨格筋:- 食道:- 胃:1.35 腸:1.14 結腸:0.93     肝臓:4.06    肺:2.34 膀胱:2.07 腎臓:- 下垂体:3.68 甲状腺:- 副腎:5.26 膵臓:1.30 乳腺:2.02 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.70 食道:- 胃:- 腸:- 結腸:-     肝臓:8.49        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_177322
Gene ID 11607
Unigene ID Mm.35062
Probe set ID -
Ensembl ID ENSMUSG00000049115

オーソログ対応遺伝子

ヒト[20]  NM_000685, NM_004835, NM_009585, NM_031850, NM_032049
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1497638
1599461
7642517
7724593
7731139
8074205
8878439
9096120
9140053
9177228
9245700
9310306
9316207
9321480
9389538
9458822
9466969
9562437
9576131
9609089
9691085
9727021
9788961
9808437
9843909
9860997
9931152
9933249
9973259
10074479
10076178
10194467
10205143
10222259
10231430
10330427
10349636
10358057
10373225
10405217
10432390
10562257
10562266
10571794
10589702
10589703
10606623
10639182
10644657
10679496
10775573
10880053
11042159
11053041
11076861
11111018
11217851
11247842
11292619
11384784
11473655
11579203
11696450
11790405
11818364
11877468
11999647
12167595
12270869
12358147
12370342
12388241
12411470
12429556
12466851
12468582
12477932
12486173
12591117
12657564
12680593
12691672
12697907
12707382
12890498
12907424
12909574
12963678
14551224
14563714
14592959
14599720
14633624
14688210
14699015
14718357
14718562
14962948
14963002
15001561
15007032
15016612
15059935
15087458
15123520
15129016
15146194
15277329
15306694
15331365
15489334
15498586
15498966
15499027
15576667
15596561
15637093
15699451
15764682
15808846
15835378
15841186
15851599
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15944203
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16001071
16023638
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16254200
16332932
16380537
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16495379
16500763
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16582578
16585392
16602821
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16738017
16888236
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17028164
17043228
17060617
17090678
17148616
17158350
17213477
17220190
17224157
17318197
17350036
17409281
17429342
17449556
17460297
17493931
17537986
17607364
17633135
17761193
17875676
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17962627
17982475
18033753
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18045833
18049031
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18180383
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19508861
19604148
19628784
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19666663
19696070
19706421
19706425
19710239
19759335
19762686
19782130
19834109
19884564
19914088
19940029
19996062
20019328
20056745
20065159
20071356
20079903
20205562
20413721
20516139
20530803
20554912
20580688
20628203
20723410
20807774
20843830
20964730
20970951
21187267
21235392
21242463
21252156
21267068
21367915
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21921024
21979434
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23034941
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23219751
23236507
23266541
23333075
23374104
23398821
23427083
23486953
23585396
23592774
23831688
24001896
24096831
24166718
24177423
24206662
24218433
24431207
24588264
24743144

遺伝子オントロジー  (GO ID)

Biological Process

GO:0042976  activation of Janus kinase activity
GO:0007200  activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0001568  blood vessel development
GO:0002035  brain renin-angiotensin system
GO:0019722  calcium-mediated signaling
GO:0060326  cell chemotaxis
GO:0042416  dopamine biosynthetic process
GO:0042756  drinking behavior
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0051482  elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007507  heart development
GO:0006954  inflammatory response
GO:0001822  kidney development
GO:0043524  negative regulation of neuron apoptosis
GO:0034392  negative regulation of smooth muscle cell apoptosis
GO:0045777  positive regulation of blood pressure
GO:0090190  positive regulation of branching involved in ureteric bud morphogenesis
GO:0008284  positive regulation of cell proliferation
GO:0032270  positive regulation of cellular protein metabolic process
GO:0010873  positive regulation of cholesterol esterification
GO:0050715  positive regulation of cytokine secretion
GO:0032430  positive regulation of phospholipase A2 activity
GO:0001921  positive regulation of receptor recycling
GO:0032930  positive regulation of superoxide release
GO:0006885  regulation of pH
GO:0002019  regulation of renal output by angiotensin
GO:0034391  regulation of smooth muscle cell apoptosis
GO:0001991  regulation of systemic arterial blood pressure by circulatory renin-angiotensin
GO:0019229  regulation of vasoconstriction
GO:0002001  renin secretion into blood stream
GO:0002018  renin-angiotensin regulation of aldosterone production
GO:0043627  response to estrogen stimulus
GO:0007266  Rho protein signal transduction
GO:0007165  signal transduction
GO:0042310  vasoconstriction

Cellular Component

GO:0016323  basolateral plasma membrane
GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0030425  dendrite
GO:0012505  endomembrane system
GO:0005768  endosome
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0031968  organelle outer membrane
GO:0005886  plasma membrane
GO:0055037  recycling endosome
GO:0031983  vesicle lumen
GO:0012506  vesicle membrane

Molecular Function

GO:0010698  acetyltransferase activator activity
GO:0001596  angiotensin type I receptor activity
GO:0004945  angiotensin type II receptor activity
GO:0031711  bradykinin receptor binding
GO:0001965  G-protein alpha-subunit binding
GO:0004930  G-protein coupled receptor activity
GO:0017046  peptide hormone binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0019901  protein kinase binding
GO:0043621  protein self-association
GO:0004871  signal transducer activity