ATPase, Cu++ transporting, alpha polypeptide

詳細情報を見る

同義遺伝子名

Menkes protein, br, Mnk, brindled, Copper pump 1, Blo, I14, Atp7a, Mo, Copper-transporting ATPase 1, DXHXS1608e, MNK, blotchy, Menkes disease-associated protein homolog, ATPase, Cu++ transporting, alpha polypeptide, mottled

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:6.90 小脳:92.10 脳幹:95.30 脳梁:- 松果体:- 末梢神経:76.40 脊柱:- 網膜:- 目:15.20 動脈:337.60 静脈:- リンパ節:86.40 末梢血:575.10 脾臓:52.70 胸腺:88.90 骨髄:- 脂肪:- 骨:25 皮膚:71.30
GeneChip 大脳:6.01 小脳:6.22 脳幹:- 脳梁:- 松果体:- 末梢神経:7.20 脊柱:6.22 網膜:9.15 目:8.73 動脈:- 静脈:8.74 リンパ節:7.69 末梢血:- 脾臓:7.59 胸腺:- 骨髄:7.45 脂肪:7.67 骨:7.51 皮膚:8.62
CAGE 大脳:2.84 小脳:- 脳幹:2.62 脳梁:- 松果体:- 末梢神経:- 脊柱:2.75 網膜:- 目:- 動脈:3.43 静脈:- リンパ節:4.09 末梢血:- 脾臓:2.90 胸腺:3.45 骨髄:- 脂肪:- 骨:2.45 皮膚:4.25
RNA-seq 大脳:1.22 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:41.40 前立腺:61.80 卵巣:34.50 精巣:29.60 心臓:- 骨格筋:71 食道:- 胃:- 腸:- 結腸:17.60     肝臓:9.10        肺:60.30    膀胱:66.20 腎臓:40.30 下垂体:- 甲状腺:- 副腎:- 膵臓:56.30 乳腺:29.40 唾液腺:-
GeneChip 子宮:7.94 胎盤:9.01 前立腺:8.87 卵巣:8.05 精巣:5.82 心臓:6.24 骨格筋:7.17 食道:- 胃:8.19 腸:8.19 結腸:- 肝臓:6.48 肺:8.28 膀胱:7.89 腎臓:7.54 下垂体:7.84 甲状腺:- 副腎:9.24 膵臓:6.32 乳腺:7.35 唾液腺:7.62
CAGE 子宮:3.64 胎盤:3.77 前立腺:3.58 卵巣:3.79 精巣:2.60 心臓:- 骨格筋:- 食道:- 胃:3.45 腸:3.82 結腸:3.65     肝臓:2.82    肺:4.02 膀胱:3.56 腎臓:- 下垂体:3.52 甲状腺:- 副腎:4.00 膵臓:2.56 乳腺:2.98 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.21 食道:- 胃:- 腸:- 結腸:-     肝臓:1.69        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_009726
Gene ID 11977
Unigene ID Mm.254297
Probe set ID 1418774_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000033792

オーソログ対応遺伝子

ヒト[2]  NM_000052
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006200  ATP catabolic process
GO:0046034  ATP metabolic process
GO:0001568  blood vessel development
GO:0001974  blood vessel remodeling
GO:0051216  cartilage development
GO:0006584  catecholamine metabolic process
GO:0006812  cation transport
GO:0006878  cellular copper ion homeostasis
GO:0021954  central nervous system neuron development
GO:0021702  cerebellar Purkinje cell differentiation
GO:0030199  collagen fibril organization
GO:0060003  copper ion export
GO:0015677  copper ion import
GO:0006825  copper ion transport
GO:0048813  dendrite morphogenesis
GO:0010273  detoxification of copper ion
GO:0042417  dopamine metabolic process
GO:0048251  elastic fiber assembly
GO:0051542  elastin biosynthetic process
GO:0042414  epinephrine metabolic process
GO:0030198  extracellular matrix organization
GO:0031069  hair follicle morphogenesis
GO:0035137  hindlimb morphogenesis
GO:0006811  ion transport
GO:0007626  locomotory behavior
GO:0048286  lung alveolus development
GO:0030001  metal ion transport
GO:0007005  mitochondrion organization
GO:0048553  negative regulation of metalloenzyme activity
GO:0043524  negative regulation of neuron apoptosis
GO:0048812  neuron projection morphogenesis
GO:0042421  norepinephrine biosynthetic process
GO:0042415  norepinephrine metabolic process
GO:0018205  peptidyl-lysine modification
GO:0043473  pigmentation
GO:0043085  positive regulation of catalytic activity
GO:0048554  positive regulation of metalloenzyme activity
GO:0051353  positive regulation of oxidoreductase activity
GO:0021860  pyramidal neuron development
GO:0010468  regulation of gene expression
GO:0002082  regulation of oxidative phosphorylation
GO:0001836  release of cytochrome c from mitochondria
GO:0019430  removal of superoxide radicals
GO:0046688  response to copper ion
GO:0042428  serotonin metabolic process
GO:0043588  skin development
GO:0042093  T-helper cell differentiation
GO:0006810  transport
GO:0006568  tryptophan metabolic process
GO:0006570  tyrosine metabolic process

Cellular Component

GO:0016323  basolateral plasma membrane
GO:0031526  brush border membrane
GO:0043025  cell soma
GO:0031410  cytoplasmic vesicle
GO:0005783  endoplasmic reticulum
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0005770  late endosome
GO:0016020  membrane
GO:0043005  neuron projection
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0030141  secretory granule
GO:0005802  trans-Golgi network
GO:0030140  trans-Golgi network transport vesicle

Molecular Function

GO:0005524  ATP binding
GO:0019829  cation-transporting ATPase activity
GO:0005507  copper ion binding
GO:0005375  copper ion transmembrane transporter activity
GO:0032767  copper-dependent protein binding
GO:0004008  copper-exporting ATPase activity
GO:0016787  hydrolase activity
GO:0046872  metal ion binding
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0016532  superoxide dismutase copper chaperone activity