BCL2-antagonist/killer 1

詳細情報を見る

同義遺伝子名

Bcl-2 homologous antagonist/killer, Bak, N-Bak, N-BAK1, Apoptosis regulator BAK, Bak1, BCL2-antagonist/killer 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:57.30 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:21.60 末梢血:- 脾臓:79 胸腺:- 骨髄:- 脂肪:- 骨:12.50 皮膚:-
GeneChip 大脳:5.04 小脳:5.09 脳幹:- 脳梁:- 松果体:- 末梢神経:5.11 脊柱:5.51 網膜:4.68 目:4.85 動脈:- 静脈:6.09 リンパ節:7.15 末梢血:- 脾臓:7.05 胸腺:- 骨髄:7.22 脂肪:5.89 骨:6.86 皮膚:4.91
CAGE 大脳:2.99 小脳:- 脳幹:3.33 脳梁:- 松果体:- 末梢神経:- 脊柱:3.49 網膜:- 目:- 動脈:4.58 静脈:- リンパ節:4.99 末梢血:- 脾臓:4.43 胸腺:4.24 骨髄:- 脂肪:- 骨:4.62 皮膚:3.98
RNA-seq 大脳:2.85 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:103.20 乳腺:3.30 唾液腺:-
GeneChip 子宮:7.31 胎盤:6.20 前立腺:5.61 卵巣:6.48 精巣:5.79 心臓:6.02 骨格筋:6.63 食道:- 胃:7.46 腸:8.47 結腸:- 肝臓:5.52 肺:6.27 膀胱:5.59 腎臓:5.51 下垂体:5.01 甲状腺:- 副腎:5.88 膵臓:5.40 乳腺:6.33 唾液腺:4.87
CAGE 子宮:4.84 胎盤:4.28 前立腺:3.38 卵巣:4.15 精巣:2.30 心臓:- 骨格筋:- 食道:- 胃:5.21 腸:5.64 結腸:5.84     肝臓:3.51    肺:4.00 膀胱:3.95 腎臓:- 下垂体:3.05 甲状腺:- 副腎:3.77 膵臓:1.84 乳腺:4.04 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:4.35 食道:- 胃:- 腸:- 結腸:-     肝臓:3.14        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_007523
Gene ID 12018
Unigene ID Mm.244305
Probe set ID 1418991_at  [Mouse430_2]
Ensembl ID ENSMUSG00000057789

オーソログ対応遺伝子

ヒト[1]  NM_001188
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

7715729
7715730
7715731
8521816
8889548
9176392
9299236
9356461
10200490
10349636
10377054
10444588
10618441
10894153
10950869
11042159
11076861
11146504
11163212
11217851
11278671
11784036
11836241
11840165
11932420
11980919
12142566
12244308
12466851
12477932
12624178
12689595
12799143
12808108
12819136
12847083
12881569
14505568
14610273
14627695
14657169
15136728
15145826
15272317
15574336
15590665
15613488
15615879
15640352
15680329
15776018
15782199
15818416
15861188
15901672
15955981
15967824
16055554
16141072
16141073
16172118
16227588
16270031
16330765
16464852
16514420
16645094
16651384
16676001
16705087
16799968
16893972
17035996
17068116
17074758
17204849
17382885
17409097
17417626
17447897
17470554
17606912
17676052
17692540
17869640
17917679
18048346
18056423
18056701
18230621
18251703
18252892
18272391
18288109
18299329
18426910
18437160
18437166
18451609
18471982
18524770
18547146
18563702
18614015
18678651
18691924
18799693
18835564
19017630
19056676
19074266
19079139
19139105
19139267
19139629
19168699
19185578
19261612
19300452
19332555
19339988
19373582
19387006
19454696
19632182
19647221
19706873
19768117
19816507
19816509
19820692
19875445
19901338
19917256
19920074
19934009
19941828
19955184
20019247
20057504
20094062
20128842
20172858
20457813
20503275
20530288
20539308
20605789
20671748
20713620
20799797
20813900
20885444
20890041
21041309
21127253
21151029
21224042
21241252
21245196
21278801
21364649
21367852
21368834
21425311
21613222
21727192
21746883
21820438
21896738
21911424
21926988
21997190
22015606
22015607
22031758
22036586
22056880
22179045
22197342
22294729
22297299
22357545
22365665
22385963
22414765
22442658
22479585
22491404
22493254
22493436
22538851
22613767
22671997
22673615
22710714
22719850
22790873
22820179
22933114
22960223
22986529
23042294
23132593
23140172
23197294
23201261
23248281
23345450
23349374
23375500
23377280
23389440
23395376
23404709
23466994
23468630
23744350
23767404
23770239
23784543
23805138
23852275
23881917
23893415
23969856
23991283
24095739
24227720
24265320
24337568
24493802
24632563

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0008635  activation of caspase activity by cytochrome c
GO:0006915  apoptosis
GO:0070059  apoptosis in response to endoplasmic reticulum stress
GO:0001783  B cell apoptosis
GO:0001782  B cell homeostasis
GO:0002352  B cell negative selection
GO:0001974  blood vessel remodeling
GO:0008283  cell proliferation
GO:0034644  cellular response to UV
GO:0008630  DNA damage response, signal transduction resulting in induction of apoptosis
GO:0010248  establishment or maintenance of transmembrane electrochemical gradient
GO:0048872  homeostasis of number of cells
GO:0001776  leukocyte homeostasis
GO:0035108  limb morphogenesis
GO:0008053  mitochondrial fusion
GO:0002262  myeloid cell homeostasis
GO:0008285  negative regulation of cell proliferation
GO:0010629  negative regulation of gene expression
GO:0033137  negative regulation of peptidyl-serine phosphorylation
GO:0043065  positive regulation of apoptosis
GO:0010524  positive regulation of calcium ion transport into cytosol
GO:0045862  positive regulation of proteolysis
GO:0090200  positive regulation of release of cytochrome c from mitochondria
GO:0048597  post-embryonic camera-type eye morphogenesis
GO:0032471  reduction of endoplasmic reticulum calcium ion concentration
GO:0042981  regulation of apoptosis
GO:0051726  regulation of cell cycle
GO:0046902  regulation of mitochondrial membrane permeability
GO:0051881  regulation of mitochondrial membrane potential
GO:0043497  regulation of protein heterodimerization activity
GO:0043496  regulation of protein homodimerization activity
GO:0001836  release of cytochrome c from mitochondria
GO:0009620  response to fungus
GO:0010332  response to gamma radiation
GO:0010046  response to mycotoxin
GO:0070242  thymocyte apoptosis
GO:0060068  vagina development

Cellular Component

GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0016021  integral to membrane
GO:0031307  integral to mitochondrial outer membrane
GO:0005622  intracellular
GO:0016020  membrane
GO:0031966  mitochondrial membrane
GO:0005739  mitochondrion
GO:0046930  pore complex

Molecular Function

GO:0051400  BH domain binding
GO:0051087  chaperone binding
GO:0031072  heat shock protein binding
GO:0042802  identical protein binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity