BCL2-associated X protein

詳細情報を見る

同義遺伝子名

Apoptosis regulator BAX, membrane isoform alpha, Bcl2-associated X protein, Bax

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:20.80

小脳:-

脳幹:31.80

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:22.80

動脈:-

静脈:-

リンパ節:-

末梢血:28.80

脾臓:39.50

胸腺:39.50

骨髄:128.20

脂肪:425.40

骨:112.70

皮膚:47.50

GeneChip

大脳:8.38

小脳:8.51

脳幹:-

脳梁:-

松果体:-

末梢神経:8.43

脊柱:8.24

網膜:6.57

目:7.08

動脈:-

静脈:8.79

リンパ節:9.53

末梢血:-

脾臓:9.53

胸腺:-

骨髄:9.07

脂肪:8.43

骨:8.66

皮膚:7.79

CAGE

大脳:3.72

小脳:-

脳幹:3.54

脳梁:-

松果体:-

末梢神経:-

脊柱:3.54

網膜:-

目:-

動脈:3.04

静脈:-

リンパ節:3.93

末梢血:-

脾臓:4.03

胸腺:3.59

骨髄:-

脂肪:-

骨:3.77

皮膚:3.33

RNA-seq

大脳:11.93

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:43.60

胎盤:82.80

前立腺:30.90

卵巣:-

精巣:-

心臓:18.60

骨格筋:-

食道:-

胃:32.70

腸:110.90

結腸:88.10

肝臓:45.30

肺:50.20

膀胱:66.20

腎臓:8.10

下垂体:25.80

甲状腺:-

副腎:2122.20

膵臓:112.60

乳腺:52.20

唾液腺:-

GeneChip

子宮:9.15

胎盤:9.15

前立腺:9.11

卵巣:9.16

精巣:6.88

心臓:7.55

骨格筋:8.06

食道:-

胃:8.84

腸:8.72

結腸:-

肝臓:8.40

肺:8.90

膀胱:8.83

腎臓:8.67

下垂体:8.47

甲状腺:-

副腎:9.28

膵臓:8.20

乳腺:8.44

唾液腺:8.34

CAGE

子宮:3.64

胎盤:4.19

前立腺:3.48

卵巣:3.52

精巣:2.85

心臓:-

骨格筋:-

食道:-

胃:3.94

腸:3.39

結腸:3.65

肝臓:3.65

肺:3.73

膀胱:3.67

腎臓:-

下垂体:3.53

甲状腺:-

副腎:3.77

膵臓:3.64

乳腺:3.58

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:2.61

食道:-

胃:-

腸:-

結腸:-

肝臓:6.83

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_007527
Gene ID	12028
Unigene ID	Mm.19904
Probe set ID	1416837_at [Mouse430_2]
Ensembl ID	ENSMUSG00000003873

オーソログ対応遺伝子

ヒト[7]	NM_004324, NM_138761, NM_138763, NM_138764
ラット[7]	NM_004324, NM_138761, NM_138763, NM_138764

染色体

遺伝子ファミリー (Interpro ID)

IPR000712	Apoptosis regulator, Bcl-2, BH
IPR002475	BCL2-like apoptosis inhibitor

遺伝子オントロジー (GO ID)

Biological Process

GO:0006919	activation of caspase activity
GO:0008635	activation of caspase activity by cytochrome c
GO:0006915	apoptosis
GO:0070059	apoptosis in response to endoplasmic reticulum stress
GO:0008637	apoptotic mitochondrial changes
GO:0001783	B cell apoptosis
GO:0001782	B cell homeostasis
GO:0002358	B cell homeostatic proliferation
GO:0002352	B cell negative selection
GO:0001974	blood vessel remodeling
GO:0008283	cell proliferation
GO:0045333	cellular respiration
GO:0071310	cellular response to organic substance
GO:0034644	cellular response to UV
GO:0021987	cerebral cortex development
GO:0006922	cleavage of lamin
GO:0045136	development of secondary sexual characteristics
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis
GO:0006309	DNA fragmentation involved in apoptosis
GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
GO:0009566	fertilization
GO:0007281	germ cell development
GO:0035234	germ cell programmed cell death
GO:0006687	glycosphingolipid metabolic process
GO:0048872	homeostasis of number of cells
GO:0048873	homeostasis of number of cells within a tissue
GO:0021854	hypothalamus development
GO:0006917	induction of apoptosis
GO:0008625	induction of apoptosis via death domain receptors
GO:0007007	inner mitochondrial membrane organization
GO:0001822	kidney development
GO:0001776	leukocyte homeostasis
GO:0035108	limb morphogenesis
GO:0008584	male gonad development
GO:0043653	mitochondrial fragmentation during apoptosis
GO:0008053	mitochondrial fusion
GO:0002262	myeloid cell homeostasis
GO:0008285	negative regulation of cell proliferation
GO:0048147	negative regulation of fibroblast proliferation
GO:0043524	negative regulation of neuron apoptosis
GO:0033137	negative regulation of peptidyl-serine phosphorylation
GO:0032091	negative regulation of protein binding
GO:0007399	nervous system development
GO:0051402	neuron apoptosis
GO:0001764	neuron migration
GO:0030264	nuclear fragmentation during apoptosis
GO:0042475	odontogenesis of dentine-containing tooth
GO:0007008	outer mitochondrial membrane organization
GO:0001541	ovarian follicle development
GO:0043065	positive regulation of apoptosis
GO:0060058	positive regulation of apoptosis involved in mammary gland involution
GO:0002904	positive regulation of B cell apoptosis
GO:0010524	positive regulation of calcium ion transport into cytosol
GO:0043525	positive regulation of neuron apoptosis
GO:0048087	positive regulation of pigmentation during development
GO:0032461	positive regulation of protein oligomerization
GO:0090200	positive regulation of release of cytochrome c from mitochondria
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
GO:0048597	post-embryonic camera-type eye morphogenesis
GO:0009791	post-embryonic development
GO:0051260	protein homooligomerization
GO:0001844	protein insertion into mitochondrial membrane during induction of apoptosis
GO:0051259	protein oligomerization
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration
GO:0042981	regulation of apoptosis
GO:0043281	regulation of caspase activity
GO:0051726	regulation of cell cycle
GO:0033599	regulation of mammary gland epithelial cell proliferation
GO:0051881	regulation of mitochondrial membrane potential
GO:0043523	regulation of neuron apoptosis
GO:0006808	regulation of nitrogen utilization
GO:0043497	regulation of protein heterodimerization activity
GO:0043496	regulation of protein homodimerization activity
GO:0001836	release of cytochrome c from mitochondria
GO:0032976	release of matrix enzymes from mitochondria
GO:0001101	response to acid
GO:0048678	response to axon injury
GO:0006974	response to DNA damage stimulus
GO:0010332	response to gamma radiation
GO:0010212	response to ionizing radiation
GO:0009651	response to salt stress
GO:0009636	response to toxin
GO:0009611	response to wounding
GO:0060041	retina development in camera-type eye
GO:0046666	retinal cell programmed cell death
GO:0060011	Sertoli cell proliferation
GO:0007548	sex differentiation
GO:0048515	spermatid differentiation
GO:0007283	spermatogenesis
GO:0001777	T cell homeostatic proliferation
GO:0070242	thymocyte apoptosis
GO:0006927	transformed cell apoptosis
GO:0060068	vagina development

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral to membrane
GO:0005622	intracellular
GO:0016020	membrane
GO:0031966	mitochondrial membrane
GO:0005741	mitochondrial outer membrane
GO:0005757	mitochondrial permeability transition pore complex
GO:0005739	mitochondrion
GO:0005634	nucleus
GO:0046930	pore complex

Molecular Function

GO:0051400	BH domain binding
GO:0051434	BH3 domain binding
GO:0015267	channel activity
GO:0051087	chaperone binding
GO:0031072	heat shock protein binding
GO:0042802	identical protein binding
GO:0008289	lipid binding
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity

BCL2-associated X protein

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function