B-cell leukemia/lymphoma 2

同義遺伝子名

D630044D05Rik, AW986256, Apoptosis regulator Bcl-2, C430015F12Rik, B-cell leukemia/lymphoma 2, Bcl-2, D830018M01Rik, Bcl2

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:36.50

小脳:-

脳幹:-

脳梁:-

松果体:257.80

末梢神経:172

脊柱:-

網膜:128.60

目:83.60

動脈:-

静脈:-

リンパ節:97.20

末梢血:186.90

脾臓:118.50

胸腺:128.40

骨髄:12.80

脂肪:-

骨:25

皮膚:79.20

GeneChip

大脳:6.48

小脳:6.22

脳幹:-

脳梁:-

松果体:-

末梢神経:7.06

脊柱:6.37

網膜:6.68

目:6.71

動脈:-

静脈:6.20

リンパ節:7.57

末梢血:-

脾臓:7.70

胸腺:-

骨髄:6.69

脂肪:6.34

骨:6.57

皮膚:6.34

CAGE

大脳:2.39

小脳:-

脳幹:2.44

脳梁:-

松果体:-

末梢神経:-

脊柱:2.54

網膜:-

目:-

動脈:3.13

静脈:-

リンパ節:4.94

末梢血:-

脾臓:3.57

胸腺:3.71

骨髄:-

脂肪:-

骨:2.83

皮膚:2.78

RNA-seq

大脳:1.00

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:87.20

胎盤:-

前立腺:-

卵巣:-

精巣:22.20

心臓:37.20

骨格筋:71

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:40.20

膀胱:-

腎臓:56.40

下垂体:129.20

甲状腺:-

副腎:-

膵臓:-

乳腺:35.90

唾液腺:-

GeneChip

子宮:7.14

胎盤:5.75

前立腺:6.23

卵巣:6.62

精巣:5.52

心臓:6.33

骨格筋:6.08

食道:-

胃:6

腸:6.20

結腸:-

肝臓:5.80

肺:6.12

膀胱:6.16

腎臓:6.39

下垂体:6.22

甲状腺:-

副腎:5.88

膵臓:6.45

乳腺:6.33

唾液腺:6.03

CAGE

子宮:3.40

胎盤:1.40

前立腺:2.31

卵巣:3.28

精巣:0.45

心臓:-

骨格筋:-

食道:-

胃:2.16

腸:1.88

結腸:2.55

肝臓:1.30

肺:3.16

膀胱:3.01

腎臓:-

下垂体:2.68

甲状腺:-

副腎:2.17

膵臓:3.36

乳腺:2.31

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.32

食道:-

胃:-

腸:-

結腸:-

肝臓:1.68

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_009741
Gene ID	12043
Unigene ID	Mm.257460
Probe set ID	1422938_at [Mouse430_2]
Ensembl ID	ENSMUSG00000057329

オーソログ対応遺伝子

ヒト[4]	NM_000633, NM_000657
ラット [0]

染色体

1E2.1 [108,434,755 - 108,610,851]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000712	Apoptosis regulator, Bcl-2, BH
IPR002475	BCL2-like apoptosis inhibitor

遺伝子オントロジー (GO ID)

Biological Process

GO:0007015	actin filament organization
GO:0006915	apoptosis
GO:0070059	apoptosis in response to endoplasmic reticulum stress
GO:0008637	apoptotic mitochondrial changes
GO:0031103	axon regeneration
GO:0007409	axonogenesis
GO:0030183	B cell differentiation
GO:0001782	B cell homeostasis
GO:0002326	B cell lineage commitment
GO:0042100	B cell proliferation
GO:0050853	B cell receptor signaling pathway
GO:0001662	behavioral fear response
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0043375	CD8-positive, alpha-beta T cell lineage commitment
GO:0007569	cell aging
GO:0008219	cell death
GO:0016049	cell growth
GO:0000902	cell morphogenesis
GO:0008283	cell proliferation
GO:0016337	cell-cell adhesion
GO:0006874	cellular calcium ion homeostasis
GO:0042149	cellular response to glucose starvation
GO:0071456	cellular response to hypoxia
GO:0071310	cellular response to organic substance
GO:0021747	cochlear nucleus development
GO:0051607	defense response to virus
GO:0048589	developmental growth
GO:0048546	digestive tract morphogenesis
GO:0043583	ear development
GO:0032469	endoplasmic reticulum calcium ion homeostasis
GO:0048041	focal adhesion formation
GO:0022612	gland morphogenesis
GO:0032835	glomerulus development
GO:0040007	growth
GO:0031069	hair follicle morphogenesis
GO:0030097	hemopoiesis
GO:0048873	homeostasis of number of cells within a tissue
GO:0002520	immune system development
GO:0008631	induction of apoptosis by oxidative stress
GO:0008625	induction of apoptosis via death domain receptors
GO:0001822	kidney development
GO:0001776	leukocyte homeostasis
GO:0002260	lymphocyte homeostasis
GO:0002320	lymphoid progenitor cell differentiation
GO:0008584	male gonad development
GO:0006582	melanin metabolic process
GO:0030318	melanocyte differentiation
GO:0014031	mesenchymal cell development
GO:0001656	metanephros development
GO:0043066	negative regulation of apoptosis
GO:0010523	negative regulation of calcium ion transport into cytosol
GO:0030308	negative regulation of cell growth
GO:0030336	negative regulation of cell migration
GO:0008285	negative regulation of cell proliferation
GO:0032848	negative regulation of cellular pH reduction
GO:0045930	negative regulation of mitotic cell cycle
GO:0033033	negative regulation of myeloid cell apoptosis
GO:0043524	negative regulation of neuron apoptosis
GO:0030279	negative regulation of ossification
GO:0033689	negative regulation of osteoblast proliferation
GO:0046671	negative regulation of retinal cell programmed cell death
GO:0051402	neuron apoptosis
GO:0048599	oocyte development
GO:0035265	organ growth
GO:0009887	organ morphogenesis
GO:0001503	ossification
GO:0001541	ovarian follicle development
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation
GO:0048753	pigment granule organization
GO:0043473	pigmentation
GO:0048066	pigmentation during development
GO:0030890	positive regulation of B cell proliferation
GO:0043085	positive regulation of catalytic activity
GO:0030307	positive regulation of cell growth
GO:0008284	positive regulation of cell proliferation
GO:0045636	positive regulation of melanocyte differentiation
GO:0040018	positive regulation of multicellular organism growth
GO:0014042	positive regulation of neuron maturation
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0048087	positive regulation of pigmentation during development
GO:0048743	positive regulation of skeletal muscle fiber development
GO:0014911	positive regulation of smooth muscle cell migration
GO:0009791	post-embryonic development
GO:0006470	protein amino acid dephosphorylation
GO:0000209	protein polyubiquitination
GO:0042981	regulation of apoptosis
GO:0051924	regulation of calcium ion transport
GO:0050790	regulation of catalytic activity
GO:0051726	regulation of cell cycle
GO:0001952	regulation of cell-matrix adhesion
GO:0010468	regulation of gene expression
GO:0010559	regulation of glycoprotein biosynthetic process
GO:0046902	regulation of mitochondrial membrane permeability
GO:0051881	regulation of mitochondrial membrane potential
GO:0006808	regulation of nitrogen utilization
GO:0048070	regulation of pigmentation during development
GO:0043067	regulation of programmed cell death
GO:0043497	regulation of protein heterodimerization activity
GO:0043496	regulation of protein homodimerization activity
GO:0032880	regulation of protein localization
GO:0031647	regulation of protein stability
GO:0022898	regulation of transmembrane transporter activity
GO:0045069	regulation of viral genome replication
GO:0001836	release of cytochrome c from mitochondria
GO:0003014	renal system process
GO:0001101	response to acid
GO:0034097	response to cytokine stimulus
GO:0006974	response to DNA damage stimulus
GO:0042493	response to drug
GO:0010332	response to gamma radiation
GO:0051384	response to glucocorticoid stimulus
GO:0042542	response to hydrogen peroxide
GO:0010039	response to iron ion
GO:0035094	response to nicotine
GO:0006979	response to oxidative stress
GO:0048545	response to steroid hormone stimulus
GO:0009636	response to toxin
GO:0010224	response to UV-B
GO:0048536	spleen development
GO:0030217	T cell differentiation
GO:0033077	T cell differentiation in the thymus
GO:0043029	T cell homeostasis
GO:0002360	T cell lineage commitment
GO:0048538	thymus development
GO:0001657	ureteric bud development

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral to membrane
GO:0005622	intracellular
GO:0016020	membrane
GO:0031966	mitochondrial membrane
GO:0005741	mitochondrial outer membrane
GO:0005739	mitochondrion
GO:0043209	myelin sheath
GO:0031965	nuclear membrane
GO:0005634	nucleus
GO:0046930	pore complex

Molecular Function

GO:0051400	BH domain binding
GO:0051434	BH3 domain binding
GO:0015267	channel activity
GO:0016248	channel inhibitor activity
GO:0042802	identical protein binding
GO:0002020	protease binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0051721	protein phosphatase 2A binding
GO:0019903	protein phosphatase binding
GO:0008134	transcription factor binding
GO:0031625	ubiquitin protein ligase binding

B-cell leukemia/lymphoma 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function