brain derived neurotrophic factor

 詳細情報を見る

同義遺伝子名

brain derived neurotrophic factor, Brain-derived neurotrophic factor precursor, BDNF, Bdnf

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:6.74 小脳:6.89 脳幹:- 脳梁:- 松果体:- 末梢神経:7.85 脊柱:5.17 網膜:5.06 目:4.52 動脈:- 静脈:5.02 リンパ節:3.52 末梢血:- 脾臓:3.57 胸腺:- 骨髄:3.61 脂肪:3.89 骨:3.61 皮膚:4.28
CAGE 大脳:2.19 小脳:- 脳幹:1.43 脳梁:- 松果体:- 末梢神経:- 脊柱:1.11 網膜:- 目:- 動脈:1.59 静脈:- リンパ節:0 末梢血:- 脾臓:0 胸腺:0 骨髄:- 脂肪:- 骨:0.63 皮膚:1.25
RNA-seq 大脳:1.99 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:81.30 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:3.87 胎盤:4.06 前立腺:3.65 卵巣:3.75 精巣:3.91 心臓:5.72 骨格筋:4.23 食道:- 胃:3.93 腸:3.69 結腸:- 肝臓:4.21 肺:7.01 膀胱:6.96 腎臓:5.20 下垂体:5.47 甲状腺:- 副腎:3.50 膵臓:4.57 乳腺:4.75 唾液腺:4.20
CAGE 子宮:0.65 胎盤:1.74 前立腺:0.20 卵巣:0.54 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0 腸:0.23 結腸:0.41     肝臓:1.70    肺:3.21 膀胱:3.00 腎臓:- 下垂体:2.63 甲状腺:- 副腎:0 膵臓:0 乳腺:1.59 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.54 食道:- 胃:- 腸:- 結腸:-     肝臓:1.32        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_007540
Gene ID 12064
Unigene ID Mm.144202
Probe set ID 1422168_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000048482

オーソログ対応遺伝子

ヒト[17]  NM_001143805, NM_001143806, NM_001143807, NM_001143808, NM_001143809, NM_001143810, NM_001143811, NM_001143812, NM_001143813, NM_001143814, NM_001143816, NM_001709, NM_170731, NM_170732, NM_170733, NM_170734, NM_170735
ラット[17]  NM_001143805, NM_001143806, NM_001143807, NM_001143808, NM_001143809, NM_001143810, NM_001143811, NM_001143812, NM_001143813, NM_001143814, NM_001143816, NM_001709, NM_170731, NM_170732, NM_170733, NM_170734, NM_170735

染色体

-

遺伝子ファミリー (Interpro ID)

IPR020430  Brain-derived neurotrophic factor
IPR020408  Nerve growth factor-like

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0007412  axon target recognition
GO:0001662  behavioral fear response
GO:0016358  dendrite development
GO:0042596  fear response
GO:0007631  feeding behavior
GO:0014047  glutamate secretion
GO:0048839  inner ear development
GO:0007611  learning or memory
GO:0042490  mechanoreceptor differentiation
GO:0006120  mitochondrial electron transport, NADH to ubiquinone
GO:0043066  negative regulation of apoptosis
GO:0007406  negative regulation of neuroblast proliferation
GO:0043524  negative regulation of neuron apoptosis
GO:0045843  negative regulation of striated muscle tissue development
GO:0021675  nerve development
GO:0007399  nervous system development
GO:0008038  neuron recognition
GO:0048170  positive regulation of long-term neuronal synaptic plasticity
GO:0045666  positive regulation of neuron differentiation
GO:0051965  positive regulation of synaptogenesis
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0048169  regulation of long-term neuronal synaptic plasticity
GO:0019222  regulation of metabolic process
GO:0043523  regulation of neuron apoptosis
GO:0046668  regulation of retinal cell programmed cell death
GO:0048172  regulation of short-term neuronal synaptic plasticity
GO:0048167  regulation of synaptic plasticity
GO:0042493  response to drug
GO:0001657  ureteric bud development

Cellular Component

GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0005576  extracellular region
GO:0048471  perinuclear region of cytoplasm
GO:0008021  synaptic vesicle

Molecular Function

GO:0008083  growth factor activity
GO:0005169  neurotrophin TRKB receptor binding
GO:0005515  protein binding
GO:0005102  receptor binding