catenin (cadherin associated protein), beta 1

詳細情報を見る

同義遺伝子名

Ctnnb1, Mesc, catenin (cadherin associated protein), beta 1, cadherin associated protein, Beta-catenin, Catnb, beta-catenin, Catenin beta-1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:659.90 小脳:386.80 脳幹:190.70 脳梁:- 松果体:1031.20 末梢神経:496.80 脊柱:662 網膜:964.30 目:995.40 動脈:- 静脈:- リンパ節:43.20 末梢血:1524 脾臓:158 胸腺:503.90 骨髄:25.60 脂肪:- 骨:501 皮膚:372.10
GeneChip 大脳:10.67 小脳:10.77 脳幹:- 脳梁:- 松果体:- 末梢神経:10.30 脊柱:10.50 網膜:6.62 目:7.48 動脈:- 静脈:11.13 リンパ節:10.59 末梢血:- 脾臓:10.39 胸腺:- 骨髄:10.29 脂肪:10.38 骨:10.40 皮膚:10.64
CAGE 大脳:5.32 小脳:- 脳幹:5.39 脳梁:- 松果体:- 末梢神経:- 脊柱:5.12 網膜:- 目:- 動脈:5.10 静脈:- リンパ節:4.62 末梢血:- 脾臓:4.64 胸腺:4.96 骨髄:- 脂肪:- 骨:4.92 皮膚:5.44
RNA-seq 大脳:32.77 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:1047 胎盤:483.30 前立腺:247.10 卵巣:988.20 精巣:391.60 心臓:316.20 骨格筋:532.60 食道:- 胃:98.20 腸:73.90 結腸:282     肝臓:36.20        肺:602.50    膀胱:794.20 腎臓:233.70 下垂体:335.80 甲状腺:337.40 副腎:4244.50 膵臓:553.60 乳腺:724.80 唾液腺:-
GeneChip 子宮:12.06 胎盤:11.41 前立腺:11.12 卵巣:11.52 精巣:9.10 心臓:10.44 骨格筋:9.86 食道:- 胃:11.17 腸:11.61 結腸:- 肝臓:10.20 肺:11.76 膀胱:11.51 腎臓:10.78 下垂体:10.60 甲状腺:- 副腎:10 膵臓:9.55 乳腺:10.55 唾液腺:8.75
CAGE 子宮:6.08 胎盤:5.90 前立腺:5.32 卵巣:5.59 精巣:4.42 心臓:- 骨格筋:- 食道:- 胃:5.27 腸:5.75 結腸:5.98     肝臓:5.23    肺:5.92 膀胱:5.92 腎臓:- 下垂体:5.23 甲状腺:- 副腎:5.75 膵臓:5.26 乳腺:5.13 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:17.30 食道:- 胃:- 腸:- 結腸:-     肝臓:23.55        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_007614
Gene ID 12387
Unigene ID Mm.291928
Probe set ID 1450008_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000006932

オーソログ対応遺伝子

ヒト[3]  NM_001098209, NM_001098210, NM_001904
ラット[1]  NM_053357, NM_001098210, NM_001904

染色体

遺伝子ファミリー (Interpro ID)

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Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0034333  adherens junction assembly
GO:0009948  anterior/posterior axis specification
GO:0045453  bone resorption
GO:0060441  branching involved in lung morphogenesis
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0003136  canonical Wnt receptor signaling pathway involved in heart induction
GO:0060038  cardiac muscle cell proliferation
GO:0060947  cardiac vascular smooth muscle cell differentiation
GO:0007155  cell adhesion
GO:0030154  cell differentiation
GO:0001709  cell fate determination
GO:0001708  cell fate specification
GO:0048469  cell maturation
GO:0000904  cell morphogenesis involved in differentiation
GO:0008283  cell proliferation
GO:0016337  cell-cell adhesion
GO:0007160  cell-matrix adhesion
GO:0009987  cellular process
GO:0034613  cellular protein localization
GO:0071363  cellular response to growth factor stimulus
GO:0071260  cellular response to mechanical stimulus
GO:0071407  cellular response to organic cyclic substance
GO:0022009  central nervous system vasculogenesis
GO:0060982  coronary artery morphogenesis
GO:0007016  cytoskeletal anchoring at plasma membrane
GO:0009950  dorsal/ventral axis specification
GO:0009953  dorsal/ventral pattern formation
GO:0007398  ectoderm development
GO:0000578  embryonic axis specification
GO:0042733  embryonic digit morphogenesis
GO:0048617  embryonic foregut morphogenesis
GO:0035115  embryonic forelimb morphogenesis
GO:0035050  embryonic heart tube development
GO:0035116  embryonic hindlimb morphogenesis
GO:0001706  endoderm formation
GO:0001711  endodermal cell fate commitment
GO:0060983  epicardium-derived cardiac vascular smooth muscle cell differentiation
GO:0060742  epithelial cell differentiation involved in prostate gland development
GO:0060066  fallopian tube development
GO:0030900  forebrain development
GO:0001702  gastrulation with mouth forming second
GO:0035112  genitalia morphogenesis
GO:0007403  glial cell fate determination
GO:0022405  hair cycle process
GO:0031069  hair follicle morphogenesis
GO:0060789  hair follicle placode formation
GO:0007507  heart development
GO:0030097  hemopoiesis
GO:0030902  hindbrain development
GO:0001701  in utero embryonic development
GO:0001822  kidney development
GO:0021819  layer formation in the cerebral cortex
GO:0002089  lens morphogenesis in camera-type eye
GO:0060173  limb development
GO:0001889  liver development
GO:0060479  lung cell differentiation
GO:0030324  lung development
GO:0060492  lung induction
GO:0060484  lung-associated mesenchyme development
GO:0030539  male genitalia development
GO:0060916  mesenchymal cell proliferation involved in lung development
GO:0003337  mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0060485  mesenchyme development
GO:0003338  metanephros morphogenesis
GO:0016331  morphogenesis of embryonic epithelium
GO:0045596  negative regulation of cell differentiation
GO:0008285  negative regulation of cell proliferation
GO:0032331  negative regulation of chondrocyte differentiation
GO:0048715  negative regulation of oligodendrocyte differentiation
GO:0045671  negative regulation of osteoclast differentiation
GO:0033234  negative regulation of protein sumoylation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0001840  neural plate development
GO:0001764  neuron migration
GO:0042475  odontogenesis of dentine-containing tooth
GO:0048599  oocyte development
GO:0048513  organ development
GO:0030316  osteoclast differentiation
GO:0031016  pancreas development
GO:0001569  patterning of blood vessels
GO:0043065  positive regulation of apoptosis
GO:0008284  positive regulation of cell proliferation
GO:0045603  positive regulation of endothelial cell differentiation
GO:0030858  positive regulation of epithelial cell differentiation
GO:0060769  positive regulation of epithelial cell proliferation involved in prostate gland development
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0045743  positive regulation of fibroblast growth factor receptor signaling pathway
GO:0010628  positive regulation of gene expression
GO:0010909  positive regulation of heparan sulfate proteoglycan biosynthetic process
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043410  positive regulation of MAPKKK cascade
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0002052  positive regulation of neuroblast proliferation
GO:0045669  positive regulation of osteoblast differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051291  protein heterooligomerization
GO:0034394  protein localization at cell surface
GO:0009954  proximal/distal pattern formation
GO:0042981  regulation of apoptosis
GO:0045595  regulation of cell differentiation
GO:0042127  regulation of cell proliferation
GO:0030997  regulation of centriole-centriole cohesion
GO:0070602  regulation of centromeric sister chromatid cohesion
GO:0030856  regulation of epithelial cell differentiation
GO:0010468  regulation of gene expression
GO:0031641  regulation of myelination
GO:0045667  regulation of osteoblast differentiation
GO:0045670  regulation of osteoclast differentiation
GO:0003266  regulation of second heart field cardioblast proliferation
GO:0048660  regulation of smooth muscle cell proliferation
GO:0042129  regulation of T cell proliferation
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0034097  response to cytokine stimulus
GO:0032355  response to estradiol stimulus
GO:0043627  response to estrogen stimulus
GO:0014010  Schwann cell proliferation
GO:0001501  skeletal system development
GO:0043588  skin development
GO:0051145  smooth muscle cell differentiation
GO:0050808  synapse organization
GO:0007268  synaptic transmission
GO:0048489  synaptic vesicle transport
GO:0030217  T cell differentiation
GO:0033077  T cell differentiation in the thymus
GO:0048538  thymus development
GO:0060440  trachea formation
GO:0060439  trachea morphogenesis
GO:0006351  transcription, DNA-dependent
GO:0001570  vasculogenesis
GO:0003223  ventricular compact myocardium morphogenesis
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005912  adherens junction
GO:0043296  apical junction complex
GO:0045177  apical part of cell
GO:0016323  basolateral plasma membrane
GO:0030877  beta-catenin destruction complex
GO:0070369  beta-catenin-TCF7L2 complex
GO:0016342  catenin complex
GO:0005938  cell cortex
GO:0030054  cell junction
GO:0031253  cell projection membrane
GO:0005913  cell-cell adherens junction
GO:0005911  cell-cell junction
GO:0005924  cell-substrate adherens junction
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0043198  dendritic shaft
GO:0030057  desmosome
GO:0005916  fascia adherens
GO:0014704  intercalated disc
GO:0009898  internal side of plasma membrane
GO:0030027  lamellipodium
GO:0016328  lateral plasma membrane
GO:0016020  membrane
GO:0031528  microvillus membrane
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0043234  protein complex
GO:0032993  protein-DNA complex
GO:0034750  Scrib-APC-beta-catenin complex
GO:0045202  synapse
GO:0005667  transcription factor complex
GO:0030018  Z disc
GO:0005915  zonula adherens

Molecular Function

GO:0045294  alpha-catenin binding
GO:0045296  cadherin binding
GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0003690  double-stranded DNA binding
GO:0019899  enzyme binding
GO:0030331  estrogen receptor binding
GO:0070411  I-SMAD binding
GO:0035255  ionotropic glutamate receptor binding
GO:0019900  kinase binding
GO:0035257  nuclear hormone receptor binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0032403  protein complex binding
GO:0019901  protein kinase binding
GO:0019903  protein phosphatase binding
GO:0070412  R-SMAD binding
GO:0046332  SMAD binding
GO:0005198  structural molecule activity
GO:0003713  transcription coactivator activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding