caveolin 1, caveolae protein

詳細情報を見る

同義遺伝子名

Cav1, caveolin, caveolae protein 1, Cav, caveolin-1, Caveolin-1, Cav-1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:38.20 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:114.70 脊柱:- 網膜:- 目:60.80 動脈:928.30 静脈:- リンパ節:- 末梢血:- 脾臓:65.80 胸腺:- 骨髄:141 脂肪:- 骨:225.40 皮膚:221.70
GeneChip 大脳:7.66 小脳:6.75 脳幹:- 脳梁:- 松果体:- 末梢神経:9.94 脊柱:8.18 網膜:8.84 目:8.65 動脈:- 静脈:13.31 リンパ節:10.48 末梢血:- 脾臓:8.69 胸腺:- 骨髄:6.19 脂肪:13.27 骨:8.90 皮膚:12.15
CAGE 大脳:2.91 小脳:- 脳幹:3.53 脳梁:- 松果体:- 末梢神経:- 脊柱:3.88 網膜:- 目:- 動脈:7.40 静脈:- リンパ節:4.56 末梢血:- 脾臓:2.89 胸腺:3.59 骨髄:- 脂肪:- 骨:4.08 皮膚:5.79
RNA-seq 大脳:5.44 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:261.70 胎盤:41.40 前立腺:61.80 卵巣:11.50 精巣:29.60 心臓:465 骨格筋:248.60 食道:- 胃:327.30 腸:- 結腸:88.10     肝臓:9.10        肺:301.30    膀胱:1853.10 腎臓:56.40 下垂体:25.80 甲状腺:- 副腎:- 膵臓:131.40 乳腺:133.90 唾液腺:162
GeneChip 子宮:11.52 胎盤:10.10 前立腺:10.97 卵巣:11.90 精巣:7.58 心臓:11.84 骨格筋:11.41 食道:- 胃:10.62 腸:10 結腸:- 肝臓:6.07 肺:13.42 膀胱:12.95 腎臓:9.06 下垂体:6.11 甲状腺:- 副腎:11.33 膵臓:9.50 乳腺:12.31 唾液腺:8.90
CAGE 子宮:5.27 胎盤:4.05 前立腺:5.11 卵巣:5.69 精巣:2.68 心臓:- 骨格筋:- 食道:- 胃:5.38 腸:4.00 結腸:4.01     肝臓:2.46    肺:7.36 膀胱:6.82 腎臓:- 下垂体:2.01 甲状腺:- 副腎:4.66 膵臓:4.54 乳腺:5.84 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:25.64 食道:- 胃:- 腸:- 結腸:-     肝臓:1.63        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_007616
Gene ID 12389
Unigene ID Mm.28278
Probe set ID 1449145_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000007655

オーソログ対応遺伝子

ヒト[2]  NM_001172895, NM_001172896, NM_001172897, NM_001753
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

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Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0055074  calcium ion homeostasis
GO:0006816  calcium ion transport
GO:0070836  caveola assembly
GO:0006874  cellular calcium ion homeostasis
GO:0071455  cellular response to hyperoxia
GO:0071260  cellular response to mechanical stimulus
GO:0033344  cholesterol efflux
GO:0042632  cholesterol homeostasis
GO:0051480  cytosolic calcium ion homeostasis
GO:0006897  endocytosis
GO:0000188  inactivation of MAPK activity
GO:0007595  lactation
GO:0019915  lipid storage
GO:0032507  maintenance of protein location in cell
GO:0030879  mammary gland development
GO:0060056  mammary gland involution
GO:0000165  MAPKKK cascade
GO:0051899  membrane depolarization
GO:0046785  microtubule polymerization
GO:0030514  negative regulation of BMP signaling pathway
GO:0008285  negative regulation of cell proliferation
GO:0001960  negative regulation of cytokine-mediated signaling pathway
GO:0001937  negative regulation of endothelial cell proliferation
GO:0030857  negative regulation of epithelial cell differentiation
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0046426  negative regulation of JAK-STAT cascade
GO:0043407  negative regulation of MAP kinase activity
GO:0043409  negative regulation of MAPKKK cascade
GO:0010656  negative regulation of muscle cell apoptosis
GO:0045665  negative regulation of neuron differentiation
GO:0045019  negative regulation of nitric oxide biosynthetic process
GO:0051001  negative regulation of nitric-oxide synthase activity
GO:0033137  negative regulation of peptidyl-serine phosphorylation
GO:0032091  negative regulation of protein binding
GO:0031397  negative regulation of protein ubiquitination
GO:0009968  negative regulation of signal transduction
GO:0048662  negative regulation of smooth muscle cell proliferation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0042524  negative regulation of tyrosine phosphorylation of Stat5 protein
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0033484  nitric oxide homeostasis
GO:0010524  positive regulation of calcium ion transport into cytosol
GO:0045807  positive regulation of endocytosis
GO:0001938  positive regulation of endothelial cell proliferation
GO:0048554  positive regulation of metalloenzyme activity
GO:0031116  positive regulation of microtubule polymerization
GO:0010952  positive regulation of peptidase activity
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0009967  positive regulation of signal transduction
GO:0045907  positive regulation of vasoconstriction
GO:0051260  protein homooligomerization
GO:0008104  protein localization
GO:0051259  protein oligomerization
GO:0030193  regulation of blood coagulation
GO:0019217  regulation of fatty acid metabolic process
GO:0052547  regulation of peptidase activity
GO:0006940  regulation of smooth muscle contraction
GO:0002026  regulation of the force of heart contraction
GO:0003057  regulation of the force of heart contraction by chemical signal
GO:0051592  response to calcium ion
GO:0043627  response to estrogen stimulus
GO:0001666  response to hypoxia
GO:0009612  response to mechanical stimulus
GO:0032570  response to progesterone stimulus
GO:0007519  skeletal muscle tissue development
GO:0031295  T cell costimulation
GO:0006641  triglyceride metabolic process
GO:0001570  vasculogenesis
GO:0042310  vasoconstriction
GO:0016050  vesicle organization

Cellular Component

GO:0002080  acrosomal membrane
GO:0016324  apical plasma membrane
GO:0009925  basal plasma membrane
GO:0016323  basolateral plasma membrane
GO:0005901  caveola
GO:0005938  cell cortex
GO:0009986  cell surface
GO:0005929  cilium
GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0005768  endosome
GO:0005925  focal adhesion
GO:0005794  Golgi apparatus
GO:0000139  Golgi membrane
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0005622  intracellular
GO:0005811  lipid particle
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005739  mitochondrion
GO:0048471  perinuclear region of cytoplasm
GO:0005778  peroxisomal membrane
GO:0005886  plasma membrane
GO:0043234  protein complex

Molecular Function

GO:0019899  enzyme binding
GO:0019900  kinase binding
GO:0050998  nitric-oxide synthase binding
GO:0005113  patched binding
GO:0016504  peptidase activator activity
GO:0005515  protein binding
GO:0005102  receptor binding
GO:0000149  SNARE binding
GO:0005198  structural molecule activity
GO:0019905  syntaxin binding