cyclin-dependent kinase inhibitor 2A

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST nodata
GeneChip 大脳:4.09 小脳:3.98 脳幹:- 脳梁:- 松果体:- 末梢神経:4.09 脊柱:4.07 網膜:4.23 目:4.47 動脈:- 静脈:4 リンパ節:4.20 末梢血:- 脾臓:4.19 胸腺:- 骨髄:4.07 脂肪:3.88 骨:4.06 皮膚:4.17
CAGE 大脳:0 小脳:- 脳幹:0 脳梁:- 松果体:- 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0.25 静脈:- リンパ節:1.73 末梢血:- 脾臓:0.62 胸腺:0.49 骨髄:- 脂肪:- 骨:0 皮膚:0.15
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST nodata
GeneChip 子宮:3.84 胎盤:4.41 前立腺:4.11 卵巣:3.91 精巣:4.10 心臓:4.52 骨格筋:4.20 食道:- 胃:3.97 腸:3.92 結腸:- 肝臓:4.16 肺:4.12 膀胱:3.95 腎臓:4.26 下垂体:4 甲状腺:- 副腎:4.03 膵臓:4.78 乳腺:4.17 唾液腺:4.57
CAGE 子宮:0.55 胎盤:1.68 前立腺:0 卵巣:0.35 精巣:2.25 心臓:- 骨格筋:- 食道:- 胃:0 腸:0 結腸:0.41     肝臓:0.26    肺:0.17 膀胱:0.18 腎臓:- 下垂体:0 甲状腺:- 副腎:0.91 膵臓:0 乳腺:0.20 唾液腺:-
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_001040654
Gene ID 12578
Unigene ID -
Probe set ID 1450140_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000044303

オーソログ対応遺伝子

ヒト[7]  NM_000077, NM_001195132, NM_058195, NM_058197
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0007568  aging
GO:0006915  apoptosis
GO:0008637  apoptotic mitochondrial changes
GO:0007569  cell aging
GO:0007049  cell cycle
GO:0007050  cell cycle arrest
GO:0000075  cell cycle checkpoint
GO:0006309  DNA fragmentation involved in apoptosis
GO:0008544  epidermis development
GO:0000082  G1/S transition of mitotic cell cycle
GO:0006917  induction of apoptosis
GO:0030889  negative regulation of B cell proliferation
GO:0045786  negative regulation of cell cycle
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0001953  negative regulation of cell-matrix adhesion
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0033088  negative regulation of immature T cell proliferation in the thymus
GO:0033600  negative regulation of mammary gland epithelial cell proliferation
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0042326  negative regulation of phosphorylation
GO:0006469  negative regulation of protein kinase activity
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0051444  negative regulation of ubiquitin-protein ligase activity
GO:0060058  positive regulation of apoptosis involved in mammary gland involution
GO:0071158  positive regulation of cell cycle arrest
GO:0043517  positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0033235  positive regulation of protein sumoylation
GO:0034393  positive regulation of smooth muscle cell apoptosis
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0031648  protein destabilization
GO:0070534  protein K63-linked ubiquitination
GO:0000209  protein polyubiquitination
GO:0050821  protein stabilization
GO:0000079  regulation of cyclin-dependent protein kinase activity
GO:0010389  regulation of G2/M transition of mitotic cell cycle
GO:0010468  regulation of gene expression
GO:0046822  regulation of nucleocytoplasmic transport
GO:0046825  regulation of protein export from nucleus
GO:0031647  regulation of protein stability
GO:0006355  regulation of transcription, DNA-dependent
GO:0042493  response to drug
GO:0014070  response to organic cyclic substance
GO:0010243  response to organic nitrogen
GO:0006364  rRNA processing
GO:0009303  rRNA transcription
GO:0048103  somatic stem cell division
GO:0035019  somatic stem cell maintenance
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0001652  granular component
GO:0005739  mitochondrion
GO:0016604  nuclear body
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0004861  cyclin-dependent protein kinase inhibitor activity
GO:0003677  DNA binding
GO:0051059  NF-kappaB binding
GO:0002039  p53 binding
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0055105  ubiquitin-protein ligase inhibitor activity