chemokine (C-C motif) receptor 2

同義遺伝子名

C-C CKR-2, CD192 antigen, CC-CKR-2, MIP-1 alphaR, CCR2A, CKR2, CCR-2, CKR2A, Cmkbr2, JE/FIC receptor, CCR2B, mJE-R, CCR2, MCP-1 receptor, C-C chemokine receptor type 2, Ccr2, CKR2B, chemokine (C-C motif) receptor 2

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:-

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:94.60

網膜:-

目:-

動脈:-

静脈:-

リンパ節:43.20

末梢血:71.90

脾臓:52.70

胸腺:-

骨髄:128.20

脂肪:425.40

骨:-

皮膚:31.70

GeneChip

大脳:3.78

小脳:3.92

脳幹:-

脳梁:-

松果体:-

末梢神経:3.95

脊柱:3.84

網膜:3.73

目:4.07

動脈:-

静脈:4.29

リンパ節:7.86

末梢血:-

脾臓:6.49

胸腺:-

骨髄:9.16

脂肪:5.97

骨:8.63

皮膚:4.20

CAGE

大脳:0.18

小脳:-

脳幹:0.37

脳梁:-

松果体:-

末梢神経:-

脊柱:0.44

網膜:-

目:-

動脈:2.75

静脈:-

リンパ節:4.29

末梢血:-

脾臓:3.13

胸腺:1.57

骨髄:-

脂肪:-

骨:3.96

皮膚:1.78

RNA-seq

大脳:0.23

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:43.60

胎盤:-

前立腺:30.90

卵巣:11.50

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:10

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:37.50

乳腺:26.10

唾液腺:-

GeneChip

子宮:6.08

胎盤:4.39

前立腺:4.23

卵巣:5.48

精巣:3.88

心臓:4.12

骨格筋:4.37

食道:-

胃:4.15

腸:4.02

結腸:-

肝臓:4.23

肺:5.60

膀胱:5.12

腎臓:4.32

下垂体:3.67

甲状腺:-

副腎:4.04

膵臓:5.01

乳腺:5.29

唾液腺:3.94

CAGE

子宮:2.50

胎盤:0.27

前立腺:1.02

卵巣:1.98

精巣:0

心臓:-

骨格筋:-

食道:-

胃:1.57

腸:0.72

結腸:1.19

肝臓:0.64

肺:3.62

膀胱:2.68

腎臓:-

下垂体:0.70

甲状腺:-

副腎:2.35

膵臓:2.03

乳腺:2.16

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:0.65

食道:-

胃:-

腸:-

結腸:-

肝臓:0.54

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_009915
Gene ID	12772
Unigene ID	Mm.6272
Probe set ID	1421187_at [Mouse430_2]
Ensembl ID	ENSMUSG00000049103

オーソログ対応遺伝子

ヒト[4]	NM_001123041, NM_001123396
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR000248	Angiotensin II receptor
IPR002237	C-C chemokine receptor, type 2
IPR002240	C-C chemokine receptor, type 5
IPR000355	Chemokine receptor
IPR017452	GPCR, rhodopsin-like superfamily

遺伝子オントロジー (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0043277	apoptotic cell clearance
GO:0001974	blood vessel remodeling
GO:0006874	cellular calcium ion homeostasis
GO:0006968	cellular defense response
GO:0019725	cellular homeostasis
GO:0070098	chemokine-mediated signaling pathway
GO:0006935	chemotaxis
GO:0019221	cytokine-mediated signaling pathway
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0002246	healing during inflammatory response
GO:0030097	hemopoiesis
GO:0006959	humoral immune response
GO:0006955	immune response
GO:0006954	inflammatory response
GO:0016525	negative regulation of angiogenesis
GO:0043310	negative regulation of eosinophil degranulation
GO:0002829	negative regulation of T-helper 2 type immune response
GO:0046641	positive regulation of alpha-beta T cell proliferation
GO:0050729	positive regulation of inflammatory response
GO:0032729	positive regulation of interferon-gamma production
GO:0032743	positive regulation of interleukin-2 production
GO:0043410	positive regulation of MAPKKK cascade
GO:0090026	positive regulation of monocyte chemotaxis
GO:0050870	positive regulation of T cell activation
GO:0010820	positive regulation of T cell chemotaxis
GO:0045627	positive regulation of T-helper 1 cell differentiation
GO:0002827	positive regulation of T-helper 1 type immune response
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
GO:0030334	regulation of cell migration
GO:0010574	regulation of vascular endothelial growth factor production
GO:0019233	sensory perception of pain
GO:0007165	signal transduction

Cellular Component

GO:0043025	cell soma
GO:0005829	cytosol
GO:0030425	dendrite
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0043204	perikaryon
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane

Molecular Function

GO:0019957	C-C chemokine binding
GO:0016493	C-C chemokine receptor activity
GO:0019956	chemokine binding
GO:0004950	chemokine receptor activity
GO:0019955	cytokine binding
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0004871	signal transducer activity

chemokine (C-C motif) receptor 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function