chemokine (C-C motif) receptor 5

詳細情報を見る

同義遺伝子名

CD195, Cmkbr5, MIP-1 alpha receptor, C-C CKR-5, chemokine (C-C motif) receptor 5, CD195 antigen, CC-CKR-5, AM4-7, C-C chemokine receptor type 5, CCR-5, Ccr5

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:20.80 小脳:- 脳幹:31.80 脳梁:- 松果体:- 末梢神経:95.50 脊柱:- 網膜:- 目:38 動脈:- 静脈:- リンパ節:43.20 末梢血:86.30 脾臓:65.80 胸腺:19.80 骨髄:12.80 脂肪:- 骨:25 皮膚:55.40
GeneChip 大脳:4.53 小脳:4.20 脳幹:- 脳梁:- 松果体:- 末梢神経:4.10 脊柱:4.41 網膜:4.32 目:4.48 動脈:- 静脈:4.30 リンパ節:6.62 末梢血:- 脾臓:5.04 胸腺:- 骨髄:5.02 脂肪:4.60 骨:4.46 皮膚:4.35
CAGE 大脳:1.73 小脳:- 脳幹:1.89 脳梁:- 松果体:- 末梢神経:- 脊柱:2.06 網膜:- 目:- 動脈:2.71 静脈:- リンパ節:4.24 末梢血:- 脾臓:2.64 胸腺:2.07 骨髄:- 脂肪:- 骨:2.19 皮膚:1.84
RNA-seq 大脳:0.82 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:13.80 前立腺:- 卵巣:23 精巣:29.60 心臓:37.20 骨格筋:- 食道:- 胃:32.70 腸:- 結腸:-     肝臓:-        肺:20.10    膀胱:132.40 腎臓:- 下垂体:77.50 甲状腺:- 副腎:- 膵臓:18.80 乳腺:49 唾液腺:-
GeneChip 子宮:5.09 胎盤:4.60 前立腺:4.13 卵巣:4.57 精巣:4.21 心臓:4.49 骨格筋:4.04 食道:- 胃:4.29 腸:4.21 結腸:- 肝臓:5.06 肺:4.39 膀胱:4.47 腎臓:4.42 下垂体:4.33 甲状腺:- 副腎:4.40 膵臓:4.32 乳腺:4.70 唾液腺:4.47
CAGE 子宮:3.17 胎盤:1.74 前立腺:1.16 卵巣:2.53 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0.67 腸:1.36 結腸:1.68     肝臓:3.02    肺:2.84 膀胱:2.42 腎臓:- 下垂体:1.40 甲状腺:- 副腎:2.84 膵臓:1.61 乳腺:2.40 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.04 食道:- 胃:- 腸:- 結腸:-     肝臓:1.50        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_009917
Gene ID 12774
Unigene ID Mm.143025
Probe set ID 1422259_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000079227

オーソログ対応遺伝子

ヒト[4]  NM_001123041, NM_001123396
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8631787
8662890
9139699
9184207
9261347
9343222
9558111
10349636
10479460
10528159
10553079
10843684
10854218
10899907
10940868
10969070
11042159
11067740
11076861
11137111
11217851
11278962
11466387
11591761
11700073
11744622
11830471
12050188
12055206
12145162
12154092
12461651
12466851
12477932
12524535
12556387
12560237
12618265
12665855
12682253
12807425
12829028
12919745
12960300
14597223
14607889
14656931
14742553
14747380
14757698
14961112
15003318
15030585
15067318
15075201
15163738
15178708
15210789
15213273
15240672
15262275
15272490
15307189
15322191
15466386
15517609
15591779
15655788
15660419
15705791
15708587
15730850
15790880
15831559
15833871
15843579
15879153
15944310
15944326
15967376
16002422
16014944
16034118
16049180
16105698
16129397
16141072
16141073
16175603
16186359
16208318
16230476
16275892
16284650
16301745
16316965
16365158
16368966
16455991
16467202
16474097
16476970
16543065
16585593
16602821
16612374
16763157
16789839
16841089
16849492
16891300
17013391
17015634
17086356
17098215
17138939
17175228
17197426
17200718
17267483
17275502
17322370
17325167
17404315
17466311
17525265
17548518
17548597
17626099
17660821
17689697
17883726
17893273
17911609
18077323
18094012
18259609
18285404
18292527
18347211
18354191
18354195
18375791
18403229
18453619
18535183
18551072
18566004
18588860
18617426
18644849
18776949
18791167
18798077
18941229
18941245
19005063
19006696
19008373
19039768
19050266
19073715
19079579
19109148
19155524
19302742
19303390
19394434
19421418
19494319
19517561
19559698
19564392
19603542
19656127
19675159
19729478
19734208
19758998
19790057
19824873
19830734
20046229
20050195
20053385
20083664
20083666
20335531
20382703
20400704
20436484
20501509
20639487
20663902
20844481
21165786
21206747
21217759
21245464
21248750
21263020
21267068
21276984
21297029
21376626
21454526
21478401
21533529
21677750
21715565
21757680
21788406
21788409
21814510
21963866
22001348
22042976
22154893
22160774
22203055
22214846
22271672
22282655
22421969
22425022
22430509
22438032
22442210
22474027
22526024
22528550
22567084
22664873
22674804
22677420
22811524
22906987
22907530
23028638
23147416
23152559
23235831
23248310
23326300
23352234
23391218
23526353
23536638
23565250
23610400
23620790
23708969
23941876
24080631
24101375
24166712
24197118
24227783
24617012

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006816  calcium ion transport
GO:0019722  calcium-mediated signaling
GO:0007267  cell-cell signaling
GO:0070098  chemokine-mediated signaling pathway
GO:0006935  chemotaxis
GO:0006952  defense response
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0006955  immune response
GO:0006954  inflammatory response
GO:0030517  negative regulation of axon extension
GO:0030336  negative regulation of cell migration
GO:0070997  neuron death
GO:0060139  positive regulation of apoptosis by virus
GO:0022409  positive regulation of cell-cell adhesion
GO:0031622  positive regulation of fever
GO:0010628  positive regulation of gene expression
GO:0050729  positive regulation of inflammatory response
GO:0050718  positive regulation of interleukin-1 beta secretion
GO:0032755  positive regulation of interleukin-6 production
GO:0045666  positive regulation of neuron differentiation
GO:0032760  positive regulation of tumor necrosis factor production
GO:0031620  regulation of fever
GO:0014808  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0070723  response to cholesterol
GO:0032496  response to lipopolysaccharide
GO:0007165  signal transduction

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005768  endosome
GO:0009897  external side of plasma membrane
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0003779  actin binding
GO:0019957  C-C chemokine binding
GO:0016493  C-C chemokine receptor activity
GO:0004950  chemokine receptor activity
GO:0004930  G-protein coupled receptor activity
GO:0001948  glycoprotein binding
GO:0019901  protein kinase binding
GO:0004871  signal transducer activity